Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation. [PDF]
PLoS Pathogens, 2009 Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is a negative-stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes fever and severe hemorrhagic illness among humans, and fever and high rates of
Tetsuro Ikegami +5 more
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Toxins, 2018 One of the deadliest mushrooms is the death cap mushroom, Amanita phalloides. The most toxic constituent is α-amanitin, a bicyclic octapeptide, which damages the liver and kidneys.
Candace S. Bever +4 more
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Alpha-1 antichymotrypsin is involved in astrocyte injury in concert with arginine-vasopressin during the development of acute hepatic encephalopathy. [PDF]
PLoS ONE, 2017 We developed a bio-artificial liver (BAL) using a radial-flow bioreactor and rescued mini-pig models with lethal acute liver failure (ALF). The point of the rescue is the recovery from hepatic encephalopathy (HE).
Jonghyuk Park +11 more
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RNA Pol II promotes transcription of centromeric satellite DNA in beetles. [PDF]
PLoS ONE, 2008 Transcripts of centromeric satellite DNAs are known to play a role in heterochromatin formation as well as in establishment of the kinetochore.
Zeljka Pezer, Durdica Ugarković
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A Sensitive, Cell-Based Assay for Measuring Low-Level Biological Activity of α-Amanitin
, 2023 α-Amanitin is one of the primary toxins produced by the poisonous mushroom genus, Amanita. Because it is odorless and tasteless, it is an important cause of death from the consumption of misidentified mushrooms.
Xiaohua He +3 more
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Single cell analysis of transcriptional activation dynamics.
PLoS ONE, 2010 BackgroundGene activation is thought to occur through a series of temporally defined regulatory steps. However, this process has not been completely evaluated in single living mammalian cells.Methodology/principal findingsTo investigate the timing and ...
Ilona U Rafalska-Metcalf +4 more
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Alpha-Amanitin Tolerance in Mycophagous Drosophila.
, 1983 Uploaded by Plazi for TaxoDros. We do not have abstracts.
Jaenike, J. +3 more
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A Comparison of the Effectiveness of Silibinin and Resveratrol in Preventing Alpha‐Amanitin‐Induced Hepatotoxicity [PDF]
Basic & Clinical Pharmacology & Toxicology, 2018 AbstractAmanita phalloides species mushrooms containing alpha‐amanitin (α‐AMA) are responsible for the majority of fatal mushroom intoxications and can lead to severe poisonings resulting in hepatotoxicity and acute hepatic failure. Existing antidotes, such as silibinin, are not sufficiently effective in the prevention and/or resolution of α‐AMA ...
Şahin, Aynur +8 more
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, 1985 CHARACTERIZATION OF WHEAT GERM RNA POLYMERASE II AMATOXIN BINDING SITES USING SELECTED DERIVATIVES OF ALPHA ...
EARL MICHAEL. AUGUST (7982558)
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Toxicokinetics of alpha amanitin in rats [PDF]
, 2012 YÖK Tez No: 340812ALFA AMANİTİNİN SIÇANLARDA TOKSİKOKİNETİĞİAmanita phalloides dünyadaki görülen ölümcül mantar zehirlenmelerinin %95'in üzerinde sorumlu olan mantar türüdür. Bu mantarın 2 grup toksini tanımlanmıştır.
Karahan, Selim
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