Deadly Poisonous Turkish Mushrooms Containing Alpha Amanitin [PDF]
Düzce Tıp Fakültesi Dergisi, 2015 Mushroom poisoning is still a serious health problem for Turkey. The mushroom species which cause fatal mushroom poisoning have been reported to contain at least 98% alpha-amanitin.
Ilgaz Akata +3 more
doaj +5 more sources
alpha-Amanitin induced apoptosis in primary cultured dog hepatocytes. [PDF]
Folia Histochemica et Cytobiologica, 2010 Amatoxin poisoning is caused by mushroom species belonging to the genera Amanita, Galerina and Lepiota with the majority of lethal mushroom exposures attributable to Amanita phalloides.
Adam Szelag +8 more
doaj +5 more sources
Effect of gut microbiota on α‐amanitin tolerance in Drosophila tripunctata [PDF]
Ecology and Evolution, 2020 The bacterial gut microbiota of many animals is known to be important for many physiological functions including detoxification. The selective pressures imposed on insects by exposure to toxins may also be selective pressures on their symbiotic bacteria,
Logan H. Griffin, Laura K. Reed
doaj +2 more sources
Alpha-Amanitin Poisoning, Nephrotoxicity and Oxidative Stress: An Experimental Mouse Model. [PDF]
Iran Red Crescent Med J, 2015 Alpha-amanitin (α-AMA) plays a major role in Amanita phalloides poisoning, showing toxic effects on multi-organs, particularly on the liver and kidneys. Studies have shown a relationship between α-AMA-related injuries and reactive oxygen species.We aimed to investigate whether there is renal injury and its relationship with oxidative stress after ...
Ergin M +5 more
europepmc +5 more sources
Effects of thymoquinone on alpha-amanitin induced hepatotoxicity in human C3A hepatocytes [PDF]
, 2022 Thymoquinone (TQ) has shown hepatoprotective effects in various experimental studies. We aimed to investigate the possible beneficial effects of TQ regarding its prevention of alpha-amanitin induced hepatotoxicity in human C3A hepatocytes.
Kaya, Ertuğrul +8 more
core +4 more sources
A Sensitive, Cell-Based Assay for Measuring Low-Level Biological Activity of α-Amanitin [PDF]
, 2023 α-Amanitin is one of the primary toxins produced by the poisonous mushroom genus, Amanita. Because it is odorless and tasteless, it is an important cause of death from the consumption of misidentified mushrooms.
Xiaohua He +3 more
core +1 more source
Non-Coding RNA, 2021 Ribosomal intergenic spacer (rIGS), located between the 45S rRNA coding arrays in humans, is a deep, unexplored source of small and long non-coding RNA molecules transcribed in certain conditions to help a cell generate a stress response, pass through a ...
Anastasia A. Sadova +2 more
doaj +1 more source
Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation. [PDF]
PLoS Pathogens, 2009 Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) is a negative-stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes fever and severe hemorrhagic illness among humans, and fever and high rates of
Tetsuro Ikegami +5 more
doaj +1 more source
Toxins, 2018 One of the deadliest mushrooms is the death cap mushroom, Amanita phalloides. The most toxic constituent is α-amanitin, a bicyclic octapeptide, which damages the liver and kidneys.
Candace S. Bever +4 more
doaj +1 more source
Alpha-1 antichymotrypsin is involved in astrocyte injury in concert with arginine-vasopressin during the development of acute hepatic encephalopathy. [PDF]
PLoS ONE, 2017 We developed a bio-artificial liver (BAL) using a radial-flow bioreactor and rescued mini-pig models with lethal acute liver failure (ALF). The point of the rescue is the recovery from hepatic encephalopathy (HE).
Jonghyuk Park +11 more
doaj +1 more source