Results 41 to 50 of about 622,381 (163)
In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley +1 more source
Alpha-amanitin-resistant transcription units in trypanosomes:a comparison of promoter sequences for a VSG gene expression site and for the ribosomal RNA genes [PDF]
Transcription of the predominant surface antigen genes in Trypanosoma brucei is unusual in its resistance to the RNA polymerase inhibitor alpha-amanitin, a property typical for rDNA transcription in eukaryotes.
Shiels, Paul G. +3 more
core +1 more source
Toxicokinetics of alpha amanitin in rats [PDF]
YÖK Tez No: 340812ALFA AMANİTİNİN SIÇANLARDA TOKSİKOKİNETİĞİAmanita phalloides dünyadaki görülen ölümcül mantar zehirlenmelerinin %95'in üzerinde sorumlu olan mantar türüdür. Bu mantarın 2 grup toksini tanımlanmıştır.
Karahan, Selim
core +1 more source
An isolable cysteine sulfenyl iodide (Cys–SI) stabilized by a molecular cradle is reported. X‐ray analysis and reactivity studies reveal hydrolysis to sulfenic acid, electrophilic substitution with indoles, and high reactivity toward amines and dimedone, providing direct evidence for long‐standing proposals on iodine‐mediated protein modification ...
Shotaro Otaka +4 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Transdermal absorption of alpha amanitin toxin from amanita phalloides in mice [PDF]
YÖK Tez No: 340816ÖZETFARELERDE AMANİTA PHALLOİDES TOKSİNİ ALFA AMANİTİNİNDERİDEN EMİLİMİMustafa Gani SÜRMENYüksek Lisans Tezi, Farmakoloji Anabilim DalıTez danışmanı Yrd. Doç. Dr.
Sürmen, Mustafa Gani
core +1 more source
The Hexagon of Alpha Chi Sigma [PDF]
Quarterly publication of the Alpha Chi Sigma chemistry fraternity containing articles related to chemistry research and the activities of the organization, including local chapters and ...
Alpha Chi Sigma, Coppola, Brian P.
core +4 more sources
ABSTRACT Food contamination poses a significant global health threat with carcinogenic potential, though the molecular pathways connecting contaminants to cancer remain poorly understood. This study sought to identify key molecular targets mediating the carcinogenic effects of nine prevalent dietary contaminants: glyphosate, perfluorooctane sulfonate ...
Bangsheng Chen +7 more
wiley +1 more source
Cultures of the rat skeletal muscle myoblast cell line, L6, were treated with the mutagen ethylmethanesulfonate and grown in the presence of alpha-amanitin, an inhibitor of RNA polymerase II in vitro. One clonal cell line, Ama102, resistant tc the cytotoxic action of 2 mu-g/ml of alpha-amanitin was isolated and extensively characterized.
D G, Somers, M L, Pearson, C J, Ingles
openaire +2 more sources
Structure of the recombinant RNA polymerase from African Swine Fever Virus
African Swine Fever Virus is a Nucleo-Cytoplasmic Large DNA Virus that causes an incurable haemorrhagic fever in pigs with a high impact on global food security.
Simona Pilotto +4 more
doaj +1 more source

