Results 141 to 150 of about 909,139 (164)

Alpha-defensins in the prevention of HIV transmission among breastfed infants.

Journal of acquired immune deficiency syndromes (1999), 2005
Alpha-defensins have been observed to have anti-HIV activity but have not been investigated in relation to mother-to-child HIV transmission. We measured the concentration of alpha-defensins in breast milk of HIV-positive mothers and tested whether the concentrations were associated with HIV transmission.
L. Kuhn, D.L. Trabattoni, C. Kankasa, K. Semrau, P. Kasonde, F. Lissoni, M. Sinkala, M. Ghosh, C. Vwalika, G. M. Aldrovandi, D. M. Thea, M.S. Clerici   +11 more
openaire   +2 more sources

[Structure and function of enteric alpha defensins in norm and pathology].

Molekuliarnaia biologiia, 2012
This review summarizes currently available data on enteric alpha defensins structure, their functions in the innate and adaptive immunity systems and the role in development of intestinal illnesses.
I G, Nikitina, Iu A, Bukurova, G S, Krasnov, E N, Grineva, V L, Karpov, N A, Lisitsyn, S F, Beresten'   +6 more
openaire   +1 more source

Alpha-defensins promote macrophage inflammatory activation via RNF31 signaling

Genes & Genomics
Defensins, small cationic peptides with strong antimicrobial activity, are key effectors of innate immunity. α-defensins, human neutrophil peptides, are produced primarily by neutrophils and serve as an essential component of the airway defense system against invading pathogens.
Jungnam, Lee, Naweed, Mohammad, Seyoung, Mun, Kyudong, Han, Tammy, Flagg-Dowie, Maria, Magallon, Mark L, Brantly, Karina A, Serban   +7 more
openaire   +2 more sources

The Molecular Determinants of Human alpha-Defensins' Biological Functions.

2010
Human alpha-defensins are cationic peptides with potent antitoxic, antimicrobial and chemotactic activities in the innate and adaptive immunity. Bacillus anthracis produces a lethal factor [LF], which is a potent toxin, capable of cell lysis. The molecular mechanism of the inhibition of LF by human alpha-defensins and the bacterial strain selectivity
openaire   +1 more source

Alpha-Defensin Offers Limited Utility in Routine Workup of Periprosthetic Joint Infection

Journal of Arthroplasty, 2021
Douglas A Dennis, Lindsay T Kleeman-Forsthuber   +1 more
exaly  

Refining the Role of Routine Synovial Alpha-Defensin in Periprosthetic Joint Infection Following Total Knee Arthroplasty: An Analysis of Limitations

Journal of Arthroplasty, 2023
Alexander B. Christ, Jay R. Lieberman, Daniel A Oakes   +2 more
exaly  

The Alpha-Defensin Prosthetic Joint Infection Test Has Poor Validity for Native Knee Joint Infection

Journal of Arthroplasty, 2021
Eric R Siegel, Simon C Mears, Jeffrey B. Stambough   +2 more
exaly  

Synovial alpha-defensin in native joints with inflammatory arthropathies

Zeitschrift für Orthopädie und Unfallchirurgie, 2020
NM Jandl, S Kleiss, W Rüther, C Iking-Konert, A Niemeier   +4 more
openaire   +1 more source

Alpha-Defensin Does Not Provide Additional Benefit Over Leukocyte Esterase in the Diagnosis of Periprosthetic Joint Infection

Expert Review of Molecular Diagnostics, 2021
Samuel J Clarkson, Javad Parvizi, Noam Shohat   +2 more
exaly  

Alpha defensins in vascular inflammation

2019
openaire   +1 more source