Results 191 to 200 of about 78,667 (269)

A Meta‐Analysis to Unveil the Diagnostic Gaps in Anderson–Fabry Disease in Women

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Anderson–Fabry disease (AFD) is an X‐linked lysosomal storage disorder caused by mutations in the GLA gene, leading to deficient α‐galactosidase A activity. Although historically considered a male disease, it is now recognized that heterozygous women can present with a wide range of symptoms. However, diagnosis in women remains challenging, as
L. Lenzini, G. Pintus, G. Gugelmo, A. P. Burlina, G. P. Fadini, A. B. Burlina, N. Vitturi   +6 more
wiley   +1 more source

Mechanistic two‐pathway modeling of substrate inhibition in lactic acid bacteria for enhanced fermentation control

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Substrate inhibition in lactic acid bacteria (LAB) fermentation occurs when substrate concentration exceeds a critical value, leading to reduced cell growth and thus inefficient lactic acid production. Many efforts, including experimental and kinetic models, have been devoted to elucidate the possible mechanisms of substrate inhibition ...
Guoxi Zheng, Junwen Mao
wiley   +1 more source

Affective and cognitive behavior in the alpha-galactosidase A deficient mouse model of Fabry disease. [PDF]

PLoS One, 2017
Hofmann L, Karl F, Sommer C, Üçeyler N.   +3 more
europepmc   +1 more source

The Prebiotic and Techno‐Functional Potential of Microbial Exopolysaccharides for Human Health and Food Systems

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak, Hye Kim, Md. Ariful Haque, Min Ji Jang, Sehyeon Song, Anishka Talari, Lakshmi Devi Chittepu, Seockmo Ku   +7 more
wiley   +1 more source

Hydrogel Composites and Their Potential Application in Animal Production and Health

Animal Research and One Health, Volume 4, Issue 1, Page 2-13, February 2026.
With emerging concerns about environmental contamination and safe animal production practices for increased animal welfare, research has increased in search of alternatives to promote sustainable production. The application of naturally derived hydrogels presents a great opportunity for exploration and application for animal production purposes ...
Victoria Anthony Uyanga, Tolulope Grace Ogundipe, Onome Ejeromedoghene, Abigail Adamma Ere‐Richard, Edikan Effiong Okon   +4 more
wiley   +1 more source

Chemical and Biological Properties of Hymenaea courbaril L.: A Review

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
PRISMA‐style flowchart showing the screening process of studies identified and selected in the review has been added to the attachments. ABSTRACT Hymenaea courbaril L., commonly known as jatobá, is a plant traditionally used by native populations for medicinal purposes, in addition to providing edible fruits and durable wood for construction.
Cicera Alane Coelho Gonçalves, Geane Gabriele de Oliveira Souza, Ana Maria Fernandes Duarte, Joice Barbosa do Nascimento, Fázia Fernandes Galvão Rodrigues, José Galberto Martins da Costa, Fabíola Fernandes Galvão Rodrigues   +6 more
wiley   +1 more source

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel, Ângela Liberal, Tiane C. Finimundy, Tânia S. P. Pires, Pedro Cravo, Maria Conceição Silva, Gustavo Capatti Cassiano, Lillian Barros, Maria M. Romeiras, Ângela Fernandes   +9 more
wiley   +1 more source

Engineering Immortalized Bovine Granulosa Cells Using a Triple‐Gene Approach: Mutant CDK4, Cyclin D1, and TERT

Cell Biology International, Volume 50, Issue 2, February 2026.
ABSTRACT Advancing reproductive technologies in livestock is essential to improve both productivity and genetic potential of cattle. Despite this importance, application of reproductive biotechnologies in cattle breeding remains limited. Bovine granulosa cells (bGCs), which are key components of the ovarian follicle, are critical in female reproduction
Lanlan Bai, Minami Takahashi, Jin Kobayashi, Takahiro Eitsuka, Himari Matsusaka, Taku Ozaki, Eriko Sugano, Hiroshi Tomita, Yuan Xu, Kazuhiro Kawamura, Kiyotaka Nakagawa, Tohru Kiyono, Tomokazu Fukuda   +12 more
wiley   +1 more source

Identification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry Disease. [PDF]

PLoS One, 2016
Citro V, Peña-García J, den-Haan H, Pérez-Sánchez H, Del Prete R, Liguori L, Cimmaruta C, Lukas J, Cubellis MV, Andreotti G.   +9 more
europepmc   +1 more source

WTAP Contributes to Periodontitis Pathogenesis by Promoting PDLSC Senescence and Impairing Osteogenic Differentiation via m6A‐Dependent Regulation of TP53BP1

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Periodontitis, a chronic inflammatory disease, represents the primary cause of tooth loss in Chinese adults. Wilms tumor 1‐associating protein (WTAP) is a key component of the N6‐methyladenosine (m6A) methyltransferase complex, and has an unclear role in periodontitis pathogenesis, particularly concerning its regulatory functions in
Menglin Xiong, Tingting Wang, Yuan Liu
wiley   +1 more source