Voglibose: An Alpha Glucosidase Inhibitor [PDF]
Journal of Clinical and Diagnostic Research, 2013 Diabetes Mellitus (DM) is a morbid disease worldwide, with increasing incidence as time passes. It has macro-vascular and micro-vascular complications. The main cause of these complications is poorly controlled postprandial hyperglycaemia.
Ajay S. Dabhi +2 more
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Foods, 2023 Alpha-glucosidase is an important target for glycemic control with the aim of reducing the risk of type 2 diabetes (T2D). Green tea catechins have been reported to inhibit alpha-glucosidase activity as a potential beverage to control blood glucose levels.
Tsukasa Orita +5 more
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Exploration of alpha-glucosidase inhibitors: A comprehensive in silico approach targeting a large set of triazole derivatives. [PDF]
PLoS ONEBackgroundThe increasing prevalence of diabetes and the side effects associated with current medications necessitate the development of novel candidate drugs targeting alpha-glucosidase as a potential treatment option.MethodsThis study employed computer ...
Oussama Abchir +6 more
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Bioactive-Guided Phytochemical Investigations, In Vitro and In Silico Alpha-Glucosidase Inhibition of Two Vietnamese Medicinal Plants Dicranopteris linearis and Psychotria adenophylla [PDF]
Pharmaceuticals, 2023 Little is known about the chemical and biological profiles of Dicranopteris linearis and Psychotria adenophylla. No previous studies have investigated alpha-glucosidase inhibition using extracts from D. linearis and P. adenophylla.
Thuc-Huy Duong +10 more
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Comparative study of alpha-glucosidase inhibition of four Vietnamese medicinal plants Combretum quadrangulare, Dicranopteris linearis, Psychotria adenophylla, and Garcinia schomburgkiana: In vitro and in vivo studies [PDF]
Biophysics and PhysicobiologyFour medicinal plants C. quadrangulare, D. linearis, P. adenophylla, and G. schomburgkiana growing in the South of Vietnam were investigated for their alpha-glucosidase inhibition. The crude methanol extract of C.
Thi-Hong-Tuoi Do +5 more
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Frontiers in Pharmacology, 2022 Background: Adequate management of diabetes in patients with liver cirrhosis can be challenging. We conducted this study to investigate the liver-related long term outcomes of alpha-glucosidase inhibitors (AGIs) in patients with diabetes and cirrhosis ...
Fu-Shun Yen +14 more
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Validation and standardization of a fluorometric method for alpha glucosidase activity assay in the detection of Pompe disease [PDF]
Reviews in Clinical Medicine, 2023 Introduction: Pompe Disease is a type of lysosomal storage disease that is caused by a deficiency of the lysosomal alpha glucosidase. Pompe disease, as a multi-systemic disorder has a broad spectrum of clinical symptoms.
Armin Mokhtariye +4 more
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Alpha-glucosidase promotes hemozoin formation in a blood-sucking bug: an evolutionary history. [PDF]
PLoS ONE, 2009 BackgroundHematophagous insects digest large amounts of host hemoglobin and release heme inside their guts. In Rhodnius prolixus, hemoglobin-derived heme is detoxified by biomineralization, forming hemozoin (Hz).
Flávia Borges Mury +11 more
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Inhibitory Effect of Mammea africana on Alpha-Amylase and Alpha-Glucosidase Enzymes of Rats
Biology, Medicine & Natural Product Chemistry, 2022 Mammea africana Sabine (Guttiferae), a medicinal plant used traditionally in the treatment of diseases including diabetes was evaluated for effect on alpha-amylase and alpha-glucosidase enzymes in vivo.
Nwakaego Omonigho Ebong +2 more
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Peptide modulators of alpha‐glucosidase [PDF]
Journal of Diabetes Investigation, 2015 AbstractAims/IntroductionAcute glucose fluctuations during the postprandial period pose great risk for cardiovascular complications and thus represent an important therapeutic approach in type 2 diabetes. In the present study, screening of peptide libraries was used to select peptides with an affinity towards mammalian intestinal alpha‐glucosidase as ...
Irena Roskar +5 more
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