Results 11 to 20 of about 225,346 (287)

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]

, 2017
Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim, Baes, Myriam, Blanz, Judith, Brügger, Britta, de Hoz, Livia, Kassmann, Celia Michèle, Kleinecke, Sandra, Kungl, Theresa, Lüchtenborg, Christian, McGonigal, Rhona, Möbius, Wiebke, Naseri, Kobra, Nave, Klaus-Armin, Quintes, Susanne, Richert, Sarah, Sachsenheimer, Timo, Sereda, Michael W., Willison, Hugh   +17 more
core   +3 more sources

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. [PDF]

, 2019
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Adams, Alfadhel, Alfadhel, Alfadhel, Aljabri, Anwar, Aronson, Arts, Attwell, Baio, Banka, Barennes, Benton, Bettendorff, Bettendorff, Biesecker, Brown, Butterworth, Butterworth, Butterworth, Calhau, Carney, Chandrakumar, Chen, Cheung, Chornyy, Chugani, Colbert, Croft, Day, De Meirleir, Fattal-Valevski, Fattal-Valevski, Fleming, Forouhi, Foulon, Foulon, Fraccascia, Fraccascia, Fraser, Frustaci, Fujita, Galvin, Ganapathy, Gangolf, Ganie, Ghaleiha, Gibson, Giulivi, Gold, Greenwood, Gu, Harel, Hiffler, Hilker, Inaba, Ishaque, Israels, Jankowska-Kulawy, Junior, Kamasak, Karabatsiakis, Kelley, Kerns, Khaw, Kitamura, Kornreich, Kril, Laforenza, Leichter, Lindhurst, Liu, Lonsdale, Lonsdale, Lonsdale, Lorber, Lu, Lukienko, Luxemburger, Lương, Ma, Magos, Mahajan, Mahmood, Martel, Martin, Mayr, McLure, Mergenthaler, Mezzar, Mimouni-Bloch, Molina, Mulholland, Mulle, Muoio, Murata, Nabokina, Nabokina, Nardone, Navarro, Nikseresht, Obrenovich, Oishi, Opdenakker, Ortega Garcia, Ortigoza-Escobar, Pepersack, Perez-Duenas, Plaitakis, Prabakaran, Prohaska, Rabie, Randle, Renthal, Rindi, Rindi, Robinson, Roust, Rubio-Lopez, Said, Schaller, Scrimshaw, Sequeira Lopes da Silva, Shi, Singleton, Siu, Skjeldal, Smidt, Society, Song, Sperringer, Spiegel, Stargrove, Subramanian, Subramanian, Sweet, Tabarki, Talwar, Thomson, Thornalley, van den Brink, Vasconcelos, Vernau, Vernau, Vimokesant, Watkins, Wendel, Whitfield, Whitfield, Wierzbicki, Williams, Yang, Zhang, Zhao, Zuccoli   +154 more
core   +2 more sources

The Prevalence of Carbon-13 in Respiratory Carbon Dioxide As an Indicator of the Type of Endogenous Substrate. The change from lipid to carbohydrate during the respiratory rise in potato slices [PDF]

, 1970
Isotope discrimination is a common feature of biosynthesis in nature, with the result that different classes of carbon compounds frequently display different 13C/12C ratios.
Epstein, Samuel, Jacobson, Bruce S., Laties, George G., Smith, Bruce N.   +3 more
core   +2 more sources

The pharmacokinetics of anthocyanins and their metabolites in humans [PDF]

, 2014
Background and Purpose: Anthocyanins are phytochemicals with reported vasoactive bioactivity. However, given their instability at neutral pH, they are presumed to undergo significant degradation and subsequent biotransformation.
Anupongsanugool, Azzini, Bell, Cardona, Cassidy, Cassidy, Czank, Das, Del Rio, Erdman, Ferrars, Forester, Garcia-Alonso, Gonzalez-Barrio, Ichiyanagi, Kay, Kay, Kay, Kim, Kim, Kim, Manach, McGhie, Min, Mink, Miyazawa, Mullen, Nardini, Nardini, Nizamutdinova, Nurmi, Pero, Rodriguez-Mateos, Stalmach, Toromanović, Vane, Vitaglione, Wang, Williamson, Wittemer, Woodward, Woodward, Xu, Zhang, Zhang, Zhang, Zhu   +46 more
core   +1 more source

Effect of alpha-tocopherol on LDL oxidation and glycation: in vitro and in vivo studies

Journal of Lipid Research, 1996
Much data support a role for both low density lipoprotein (LDL) oxidation and glycation in atherogenesis. While alpha-tocopherol decreases the oxidative susceptibility of LDL, its role in decreasing LDL glycation is unclear. Hence we tested the effect of
D Li, S Devaraj, C Fuller, R Bucala, I Jialal   +4 more
doaj   +1 more source

Safety assessment of the mixture of methyl-branched and linear C14–C18 alkanamides, derived from fatty acids, for use in food contact materials [PDF]

, 2017
Publisher ...
Barthélemy, Eric, Bolognesi, Claudia, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, Engel, Karl-Heinz, Fowler , Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kolf-Clauw, Martine, Kärenlampi, Sirpa, Lampi, Eugenia, Mennes, Wim, Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Svensson, Kettil, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +24 more
core   +3 more sources

Role of apolipoprotein B-derived radical and alpha-tocopheroxyl radical in peroxidase-dependent oxidation of low density lipoprotein.

Journal of Lipid Research, 1995
The peroxidation of low density lipoprotein (LDL) may play an important role in the modification of the lipoprotein to an atherogenic form. The oxidation of LDL by peroxidases has recently been suggested as a model for in vivo transition metal ion ...
B Kalyanaraman, V Darley-Usmar, A Struck, N Hogg, S Parthasarathy   +4 more
doaj   +1 more source

Phytanic acid alpha-oxidation: accumulation of 2-hydroxyphytanic acid and absence of 2-oxophytanic acid in plasma from patients with peroxisomal disorders.

Journal of Lipid Research, 1992
A stable isotope dilution method was developed for the measurement of 2-hydroxyphytanic acid and 2-oxophytanic acid in plasma. In plasma from healthy individuals and from patients with Refsum's disease, 2-hydroxyphytanic acid was found at levels less ...
HJ ten Brink, DS Schor, RM Kok, BT Poll-The, RJ Wanders, C Jakobs   +5 more
doaj   +1 more source

Sulfur isotope fractionation during heterogeneous oxidation of SO₂ on mineral dust [PDF]

Atmospheric Chemistry and Physics, 2012
Mineral dust is a major fraction of global atmospheric aerosol, and the oxidation of SO2 on mineral dust has implications for cloud formation, climate and the sulfur cycle.
P. Hoppe, J. N. Crowley, S. Borrmann, S. Foley, B. Sinha, E. Harris   +5 more
doaj   +1 more source

ACBD5 deficiency causes a defect in peroxisomal very long-chain fatty acid metabolism [PDF]

, 2016
Background Acyl-CoA binding domain containing protein 5 (ACBD5) is a peroxisomal membrane protein with a cytosolic acyl-CoA binding domain. Because of its acyl-CoA binding domain, ACBD5 has been assumed to function as an intracellular carrier of acyl ...
Falkenberg, K, KF, Ferdinandusse, S, SF, Jones, R, RJ, Koster, J, JK, Mooyer, PM, Pizzino, A, AP, Schrader, M, van Roermund, C, C, Vanderver, A, AV, Wanders, R, RW, Waterham, H, HW   +10 more
core   +1 more source