Results 1 to 10 of about 2,283 (151)
Phytanic acid, an inconclusive phytol metabolite: A review [PDF]
Current Research in Toxicology, 2023 Phytanic acid (PA: 3,7,11,15-tetramethylhexadecanoic acid) is an important biometabolite of the chlorophyll-derived diterpenoid phytol. Its biological sources (occurrence) and ADME (absorption, distribution, metabolism, and elimination) profile are well ...
Muhammad Torequl Islam +5 more
doaj +4 more sources
Phytol/Phytanic acid and insulin resistance: potential role of phytanic acid proven by docking simulation and modulation of biochemical alterations. [PDF]
PLoS ONE, 2013 Since activation of PPARγ is the main target for the antidiabetic effect of TZDs, especially when it heterodimerizes with RXR, we aimed to test the potential antidiabetic effect of phytol (250 mg/kg), the natural precursor of phytanic acid, a RXR ligand ...
Mohamed M Elmazar +3 more
doaj +5 more sources
Effect of phytol in forage on phytanic acid content in cow’s milk [PDF]
Animal Bioscience, 2021 Objective Bioactive compounds in ruminant products are related to functional compounds in their diets. Therefore, this study aimed to explore the effect of forage sources, Italian ryegrass (IR) silage vs corn silage (CS) in the total mixed ration (TMR ...
Renlong Lv +4 more
doaj +2 more sources
Effect of dairy fat on plasma phytanic acid in healthy volunteers - a randomized controlled study [PDF]
Lipids in Health and Disease, 2011 Background Phytanic acid produced in ruminants from chlorophyll may have preventive effects on the metabolic syndrome, partly due to its reported RXR and PPAR- α agonist activity.
Drachmann Tue +6 more
doaj +2 more sources
Journal of Lipid Research, 1966 Preparation of methyl phytanate from phytol by catalytic hydrogenation and chromic oxide oxidation is described. The method was applied to the preparation of methyl phytanate-14C.
Stuart Patton, A.A. Benson
doaj +3 more sources
Phytanic acid and the risk of non-Hodgkin lymphoma [PDF]
Carcinogenesis, 2012 Greater consumption of red meat, processed meat and dairy products has been associated with an increased risk of non-Hodgkin lymphoma (NHL) in several previous reports. Phytanic acid, a saturated fatty acid obtained primarily through the consumption of ruminant meat and dairy products, may offer a potential underlying mechanism for these associations ...
Nicholas J, Ollberding +6 more
openaire +3 more sources
Effects of dietary phytol and phytanic acid in animals
Journal of Lipid Research, 1966 Feeding of phytol in large doses (2-5% by weight in the diet) led to accumulation of phytanic acid in the mouse, rat, rabbit, and chinchilla, the degree of accumulation depending upon the level of dietary intake.
Daniel Steinberg +6 more
doaj +3 more sources
Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells [PDF]
Lipids in Health and Disease, 2013 Background Humans and rodents with impaired phytanic acid (PA) metabolism can accumulate toxic stores of PA that have deleterious effects on multiple organ systems.
Moser Ann B +7 more
doaj +2 more sources
Journal of Lipid Research, 1995 To understand the possible role of phytanoyl-CoA ligase, present in the membrane, in the oxidation of phytanic acid in the matrix of peroxisomes (Pahan, K. and I. Singh. 1993. FEBS Lett.
K Pahan, I Singh
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Phytanic Acid is a Retinoid X Receptor Ligand [PDF]
FEBS Journal, 1996 Metabolic defects in phytanic acid catabolism have been shown to be connected with a number of human diseases which can lead to lethal defects of the nervous system and other organs. These effects are probably a result of the very high accumulation of phytanic acid in tissues throughout the body, due to defects in phytanic acid oxidation, the ...
P K, Lemotte, S, Keidel, C M, Apfel
exaly +3 more sources