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Chemischer Informationsdienst, 1974
AbstractR 0030 Die Oxirane des Typs (I) reagieren mit Methanol unter Bildung der Produkte (II).
R. A. BEKKER +3 more
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AbstractR 0030 Die Oxirane des Typs (I) reagieren mit Methanol unter Bildung der Produkte (II).
R. A. BEKKER +3 more
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Phytanic acid alpha-oxidation, new insights into an old problem: a review
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2003Phytanic acid (3,7,10,14-tetramethylhexadecanoic acid) is a branched-chain fatty acid which is known to accumulate in a number of different genetic diseases including Refsum disease. Due to the presence of a methyl-group at the 3-position, phytanic acid and other 3-methyl fatty acids can not undergo beta-oxidation but are first subjected to fatty acid ...
Ronald J A, Wanders +2 more
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Alpha-oxidation of fatty acids in fasted or diabetic rats
Diabetes Research and Clinical Practice, 1992Induction of alpha-oxidation, a possible gluconeogenic process, which should produce odd-chain fatty acids from even-chain fatty acids, was studied in rats fasted or made diabetic with streptozotocin. When a omega-phenylated even-chain fatty acid, phenylbutyric acid (1.2 mmol/kg), was administered to rats under these conditions, a significant increase ...
T, Takahashi +3 more
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Human Genetics, 1989
We have measured the production of 14CO2 from exogenous [1-14C] phytanic acid in fibroblast monolayers from patients with classical Refsum's disease and peroxisomal disorders. Activities in the different disorders were (percentage of control): classical Refsum's disease (5%), isolated peroxisomal acyl-CoA oxidase deficiency (75%), Zellweger syndrome (4%
Poll-The, B. T. +5 more
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We have measured the production of 14CO2 from exogenous [1-14C] phytanic acid in fibroblast monolayers from patients with classical Refsum's disease and peroxisomal disorders. Activities in the different disorders were (percentage of control): classical Refsum's disease (5%), isolated peroxisomal acyl-CoA oxidase deficiency (75%), Zellweger syndrome (4%
Poll-The, B. T. +5 more
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Scandinavian Journal of Clinical and Laboratory Investigation, 1967
Patients with Refsum's disease, who accumulate phytanic acid, have a reduced capacity for α-oxidation of branched chain fatty acids. To try to elucidate the role of phytanic acid in the symptomatology of this disease, a phytanic acid feeding experiment in animals has been performed.
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Patients with Refsum's disease, who accumulate phytanic acid, have a reduced capacity for α-oxidation of branched chain fatty acids. To try to elucidate the role of phytanic acid in the symptomatology of this disease, a phytanic acid feeding experiment in animals has been performed.
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Studies on alpha oxidation of stearic acid by Tetrahymenapyriformis and Crithidiafasiculata
Biochemical and Biophysical Research Communications, 1968Abstract Metabolism of fatty acids by alpha oxidation occurs in mammals ( Fulco and Mead, 1961 ), and failure of normal alpha oxidative mechanisms is associated with Refsum's syndrome, a neurological disease of man ( Steinberg, 1967 ). Whether alpha oxidation is important or even exists in lower animals is unknown. The present study was undertaken to
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THE ROLE OF ALPHA OXIDATION IN LIPID METABOLISM
2018Recent findings have shown an inverse association between the circulating levels of pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) with the risk of pathological development in type 2 diabetes, cardio vascular disease and neurological disorders.
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Chemischer Informationsdienst. Organische Chemie, 1971
AbstractDie Alkylglycidylmalonester (I) reagieren mit Acetessigsäureäthylester in Gegenwart von Na‐äthylat in Äthanol bei 65°C zu den Valerolactonen (II) (Ausbeute 61‐68%).
E. G. MESROPYAN +2 more
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AbstractDie Alkylglycidylmalonester (I) reagieren mit Acetessigsäureäthylester in Gegenwart von Na‐äthylat in Äthanol bei 65°C zu den Valerolactonen (II) (Ausbeute 61‐68%).
E. G. MESROPYAN +2 more
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The mechanism of α-oxidation in leaves
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1966Abstract 1. 1. The oxidation of [ 14 C 16 ]palmitate and of dl -2-hydroxy[ 14 C 16 ]palmitate by particulate fractions and by acetone-dried powders of young green leaves has been investigated. 2. 2. [ 14 C 16 ]Palmitate was converted to 2-hydroxy[ 14 C]palmitate, [ 14 C]pentadecanoate, 2-hydroxy[ 14 C]pentadecanoate, [ 14 C]myristate and 2 ...
C, Hitchcock, A T, James
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Peroxisomal lipid degradation via beta- and alpha-oxidation in mammals.
Cell biochemistry and biophysics, 2001Peroxisomal beta-oxidation is involved in the degradation of long chain and very long chain fatty acyl-(coenzyme A)CoAs, long chain dicarboxylyl-CoAs, the CoA esters of eicosanoids, 2-methyl-branched fatty acyl-CoAs (e.g. pristanoyl-CoA), and the CoA esters of the bile acid intermediates di- and trihydroxycoprostanic acids (side chain of cholesterol ...
G P, Mannaerts +2 more
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