Results 31 to 40 of about 225,346 (287)

Phytanic acid alpha oxidation in rat liver: Studies on alpha hydroxylation

International Journal of Biochemistry, 1987
1. The alpha-hydroxylation of [1-14C]phytanic acid was investigated in the postnuclear fraction of rat liver. 2. The reaction required ATP, Mg, Fe3+ and molecular oxygen. Fe3+ could be replaced by Fe2+. 3. The hydroxylase activity was optimal at pH 7.5 in phosphate buffer. 4.
F N, Muralidharan, V B, Muralidharan
openaire   +2 more sources

Phytosphingosine degradation pathway includes fatty acid alpha-oxidation reactions in the endoplasmic reticulum [PDF]

, 2017
Although normal fatty acids (FAs) are degraded via beta-oxidation, unusual FAs such as 2-hydroxy (2-OH) FAs and 3-methyl-branched FAs are degraded via alpha-oxidation.
Kihara, Akio, Kitamura, Takuya, Seki, Naoya   +2 more
core   +1 more source

Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper

Journal of Lipid Research, 1996
Oxidation of low density lipoprotein (LDL) in the artery wall leads to the formation of cholesterol oxidation products that may result in cytotoxicity.
R P Patel, U Diczfalusy, S Dzeletovic, M T Wilson, V M Darley-Usmar   +4 more
doaj   +1 more source

Hydrogen Peroxide Production by Streptococcus pneumoniae Results in Alpha-hemolysis by Oxidation of Oxy-hemoglobin to Met-hemoglobin

mSphere, 2020
Streptococcus pneumoniae and other streptococci produce a greenish halo on blood agar plates referred to as alpha-hemolysis. This phenotype is utilized by clinical microbiology laboratories to report culture findings of alpha-hemolytic streptococci ...
Erin McDevitt, Faidad Khan, Anna Scasny, Courtney D. Thompson, Zehava Eichenbaum, Larry S. McDaniel, Jorge E. Vidal   +6 more
doaj   +1 more source

Tissue Proteome of 2-Hydroxyacyl-CoA Lyase Deficient Mice Reveals Peroxisome Proliferation and Activation of ω-Oxidation [PDF]

, 2022
Peroxisomal fatty acid α-oxidation is an essential pathway for the degradation of β-carbon methylated fatty acids such as phytanic acid. One enzyme in this pathway is 2-hydroxyacyl CoA lyase (HACL1), which is responsible for the cleavage of 2 ...
Aguilar, C, Al-Shawi, R, Banks, G, Blease, A, Carrino, S, Clayton, PT, Concas, D, Falcone, S, Ferlin, A, Gale, DP, Haynes, AR, Heywood, W, Khalil, Y, Lad, HV, Lin, F, Mazzacuva, F, Mills, K, Nicol, T, Potter, P, Rivers, N   +19 more
core   +1 more source

From ether to acid: a plausible degradation pathway of glycerol dialkyl glycerol tetraethers [PDF]

, 2016
Glycerol dialkyl glycerol tetraethers (GDGTs) are ubiquitous microbial lipids with extensive demonstrated and potential roles as paleoenvironmental proxies.
Baugh, Baugh, Becker, Birgel, Birgel, Birgel, Birgel, Brocks, Chappe, Chuanlun Zhang, Clari, Clari, Daniel Birgel, Elling, Felix J. Elling, Feng, Gutierrez, Harvey, Huguet, Inagaki, Innes, Jansen, Julius S. Lipp, Jörn Peckmann, Kai-Uwe Hinrichs, Knappy, Knappy, Kuypers, Könneke, Lengger, Lipp, Liu, Liu, Liu, Lunau, Lutnaes, Lutnaes, Mackenzie, Martens-Habbena, Martin Könneke, Meador, Meador, Meunier-Christman, Moldowan, Morii, Paul A. Sutton, Pearson, Pearson, Pease, Peckmann, Peters, Roger E. Summons, Rong Zhu, Rontani, Rowland, Saito, Sandy, Schouten, Schouten, Schouten, Schouten, Schouten, Steven J. Rowland, Stickland, Sturt, Sutton, Sutton, Teske, Thiel, Weijers, Wuchter, Xiao-Lei Liu, Xie, Yang, Yoshinaga, Zhu, Zhu   +76 more
core   +2 more sources

Competitive inhibition of side chain oxidation of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid by 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestan-26-oic acid in the hamster.

Journal of Lipid Research, 1980
3 alpha,7 alpha-dihydroxy-5 beta-cholestan-26-oic acid (DHCA) and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid (THCA) are metabolized into chenodeoxycholic acid and cholic acid, respectively, through oxidation and cleavage of the ...
O W Cass, G C Williams, R F Hanson
doaj   +1 more source

The Relationship between Body Composition, Fatty Acid Metabolism and Diet in Spinal Muscular Atrophy [PDF]

, 2021
Acknowledgments: I.B. received a studentship from SMA Angels Charity. M.B.’s SMA research isfunded by SMA Angels Charity, Muscular Dystrophy UK, Action Medical Research and SMA UK. S.H.P.’s SMA research is funded by SMA Europe and Anatomical Society.Peer
Boukhloufi,, Imane, Bowerman, Melissa, Parson, Simon H, Watson, Katherine S   +3 more
core   +2 more sources

High Sensitivity 1H-NMR Spectroscopy of Homeopathic Remedies Made in Water [PDF]

, 2011
Background: The efficacy of homeopathy is controversial. Homeopathic remedies are made via iterated shaking and dilution, in ethanol or in water, from a starting substance. Remedies of potency 12 C or higher are ultra-dilute (UD), i.e.
Anick, David Jay
core   +1 more source

Circulating fatty acids and endocannabinoidome-related mediator profiles associated to human longevity [PDF]

, 2021
To evaluate whether a peculiar plasma profile of fatty acids and endocannabinoidome (eCBome)-related mediators may be associated to longevity, we assessed them in octogenarians (Old; n=42) living in the east-central mountain area of Sardinia, a High ...
Abolghasemi A., Ansar H., Banni S., Cani P. D., Carta G., Errigo A., Manca C., Murru E., Pes G. M.   +8 more
core   +1 more source