Results 231 to 240 of about 68,100 (329)

Early Autonomic Burden in Prodromal Parkinson's Disease Predicts Cognitive Impairment

Movement Disorders, EarlyView.
Abstract Background Autonomic dysfunction is a known contributor to cognitive impairment in Parkinson's disease (PD), but its impact during prodromal stage is unknown. Objective The aim was to determine whether early autonomic burden predicts incident cognitive impairment in prodromal PD.
A. Enrique Martinez‐Nunez, Kelly A. Mills, Joseph Seemiller, Christopher B. Morrow, Gregory M. Pontone, Abhimanyu Mahajan   +5 more
wiley   +1 more source

Evaluation of an antibody panel for alpha-synuclein detection in FFPE rectal biopsies in Parkinson's disease. [PDF]

IBRO Neurosci Rep
Schröder K, Kintrup C, Kulcsárová K, Heinzel S, Kluge A, Wedel T, Böttner M, Lucius R, Pendziwiat M, Schoch S, Ellrichmann M, Berg D, Schaeffer E, Cossais F.   +13 more
europepmc   +1 more source

Ow949 Zgis125[P(Dat-1)::Alpha-Synuclein::Yfp] | 2014-02-27T08:32:28+01:00

, 2018
Céline N. Martineau, Ellen A. A. Nollen
openalex   +1 more source

Alpha Synuclein Protein Measurement [PDF]

, 2020
openaire   +1 more source

Plasma Glucosylsphingosine in GBA1 E365K, N409S, and L483P Heterozygous Mutation Carriers

Movement Disorders, EarlyView.
Abstract Background GBA1 encodes the lysosomal enzyme glucocerebrosidase, with key substrates that include glucosylceramide and glucosylsphingosine. The E365K variant is the most common variant in GBA1 that is associated with Parkinson's disease (PD) but is not associated with Gaucher disease.
Julian Agin‐Liebes, Alexander Haimovich, Rachel Griep, Nathan Galen Hatcher, Lihang Yao, Cheryl Waters, Shalini Padmanabhan, Roy N. Alcalay   +7 more
wiley   +1 more source

Elevated plasma levels of alpha-synuclein are dispensable for Parkinson's disease pathology. [PDF]

NPJ Parkinsons Dis
Jeong JY, Kim N, Li Y, Kim DJ, Kim HK, Oh WJ.   +5 more
europepmc   +1 more source

Challenges and Opportunities in State‐of‐the‐Art Proteomics Analysis for Biomarker Development From Plasma Extracellular Vesicles

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup, Ivo Diaz Ludovico, Youngki You, Chaitra Rao, Javier Flores, Lisa M. Bramer, Marian Rewers, Bobbie‐Jo M. Webb‐Robertson, Thomas O. Metz, Raghavendra G. Mirmira, Emily K. Sims, Ernesto S. Nakayasu   +11 more
wiley   +1 more source

Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria. [PDF]

Nat Commun
Serdiuk T, Fleischmann Y, Ghosh D, Delparente A, Reber V, Frey L, Rhyner D, Gerez J, Volkmar N, Kralickova L, Mas G, Dörig C, Hiller S, Schibli R, Mu L, Picotti P, Riek R.   +16 more
europepmc   +1 more source

[11C]MODAG 005 – a PET tracer targeting alpha-synuclein aggregates in the brain

Ran Sing Saw, Sabrina Buss, Felix Schmidt, Sergey Ryazanov, Andrei Leonov, Daniel Bleher, Ann-Kathrin Grotegerd, Laura Kuebler, Benjamin Röeben, Fabian Schmidt, Matthias Reimold, Federica Bonanno, Viktoria Ruf, Bernadette Dahl, Christine Sandiego, Kelly E. Henry, Ioannis Papadopoulos, Martin Schaller, Philipp J. Kahle, Johannes Levin, Thomas Gasser, Kathrin Brockmann, Gerald Reischl, Christian la Fougère, Bernd J. Pichler, Andreas Maurer, Christian Griesinger, Armin Giese, Kristina Herfert   +28 more
openalex   +1 more source