Results 241 to 250 of about 1,144,970 (369)

Alpha-Synuclein Aggregation Induced by Brief Ischemia Negatively Impacts Neuronal Survival in vivo: A Study in [A30P]alpha-Synuclein Transgenic Mouse [PDF]

, 2010
Isın Ünal-Çevik, Yasemin Özdemir, Müge Yemişçi, Sevda Lüle, Günfer Gürer, Alp Can, Verónica Müller, Philip J Kahle, Turgay Dalkara   +8 more
openalex   +1 more source

Alpha-synuclein overexpression does not cause vocalization deficits in a mouse model of parkinsonism. [PDF]

Biol Open
Rodgers B, Schaser A.
europepmc   +1 more source

Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia [PDF]

, 2010
Jonathan Wills, Jessica M. Jones, Thomas Haggerty, Valeriy Duka, Jeffrey N. Joyce, Anita Sidhu   +5 more
openalex   +1 more source

Impaired Glymphatic Clearance, Measured Using Diffusion Tensor Image Analysis Along the Perivascular Space (DTI‐ALPS), is Linked to Poor Cognitive Outcomes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Impaired glymphatic clearance may contribute to pathological accumulations in Parkinson's (PD), but how it interacts with other processes causing dementia remains unclear. Diffusion tensor image analysis along the perivascular space (DTI‐ALPS) has been proposed as an indirect proxy for glymphatic clearance. Objectives To clarify DTI‐
Angeliki Zarkali, George Thomas, Ross Paterson, Naomi Hannaway, Ivelina Dobreva, Amanda J. Heslegrave, Elena Veleva, Henrik Zetterberg, Rimona S. Weil   +8 more
wiley   +1 more source

Expression of human A53T alpha-synuclein without endogenous rat alpha-synuclein fails to elicit Parkinson's disease-related phenotypes in a novel humanized rat model. [PDF]

PLoS One
Polinski NK, Puoliväli J, Rauhala L, Stenius TK, Bragge T, Parkkari T, Penttinen AM, Chen Y, Mabrouk OS, Glajch KE, Hirst WD, Perkinton M, Martinez TN, Frasier MA.   +13 more
europepmc   +1 more source

Spinal Cord Pathology in Alpha-Synuclein Transgenic Mice [PDF]

, 2010
S. Mendritzki, Saskia Schmidt, Teresa Sczepan, Xin‐Ran Zhu, Daniel Segelcke, Hermann Lübbert   +5 more
openalex   +1 more source

Electrophysiological Evidence for Impaired Central Pain Modulation in Parkinson's Disease

Movement Disorders, EarlyView.
Our study demonstrates electrophysiological evidence of impaired central pain modulation in Parkinson's disease (PD) patients using laser‐evoked potential habituation and quantitative sensory testing. PD patients exhibited reduced habituation to painful stimuli, independent of reported pain or medication.
Dilara Kersebaum, Josephine Lassen, Julia Forstenpointner, Manon Sendel, Sophie‐Charlotte Fabig, Sonja Nölker, Juliane Sachau, Steffen Paschen, Daniela Berg, Ralf Baron, Philipp Hüllemann   +10 more
wiley   +1 more source

Alpha-synuclein modulates the positioning of endolysosomes in melanoma cells. [PDF]

Hum Mol Genet
Aloy NM, Ericsson M, Hartman B, Witt SN.
europepmc   +1 more source

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity.

, 2000
Natalie Ostrerova-Golts, Leonard Petrucelli, John Hardy, J.M. Lee, Matthew Farer, Benjamin Wolozin   +5 more
openalex  

Mitochondrial association of alpha-synuclein causes oxidative stress

, 2008
Mordhwaj S. Parihar, Abhinav Parihar, Masayo Fujita, Makoto Hashimoto, Pedram Ghafourifar   +4 more
openalex   +1 more source