Results 251 to 260 of about 68,100 (329)

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x‐ray phase‐contrast tomography

open access: yesBrain Pathology, EarlyView.
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz   +9 more
wiley   +1 more source

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease [PDF]

open access: yes, 2018
Bateman, Randall J   +5 more
core   +1 more source

Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study

open access: yesBrain Pathology, EarlyView.
We investigated neuropathological manifestations of hypothermia in 168 cases. Patients aged 65 years or more constituted 80% of the total cohort. Alzheimer's disease was the most common comorbidity, affecting 40% of all patients. Abstract There is a paucity of autopsy‐based studies providing detailed neuropathological characteristics of fatal ...
Shojiro Ichimata   +2 more
wiley   +1 more source

Alpha-synuclein deposition patterns in Alzheimer's disease: association with cortical amyloid beta and variable tau load. [PDF]

open access: yesActa Neuropathol
Neubauer A   +7 more
europepmc   +1 more source

Neuronal alpha-synuclein-mediated autophagy drives lipid droplets accumulation in astrocytes and microglia and aggravates ischemic stroke

open access: gold
Wenqiang Xin   +11 more
openalex   +2 more sources

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