Results 91 to 100 of about 5,528 (200)

Synthesis of potential cholelitholytic agents: 3 alpha,7 alpha,12 alpha-trihydroxy-7 beta-methyl-5 beta-cholanoic acid, 3 alpha,7 beta,12 alpha-trihydroxy-7 alpha-methyl-5 beta-cholanoic acid, and 3 alpha,12 alpha-dihydroxy-7 xi-methyl-5 beta-cholanoic acid.

Journal of Lipid Research, 1985
This report describes the chemical synthesis of six new bile acid analogs, namely, 3 alpha,7 alpha,12 alpha-trihydroxy-7 beta-methyl-5 beta-cholanoic acid (7 beta-methyl-cholic acid), 3 alpha,7 beta,12 alpha-trihydroxy-7 alpha-methyl-5 beta-cholanoic ...
S Kuroki, M Une, E H Mosbach
doaj   +1 more source

Association of nicotinic acetylcholine receptors with central respiratory control in isolated brainstem-spinal cord preparation of neonatal rats

Biological Research, 2006
Nicotine exposure is a risk factor in several breathing disorders Nicotinic acetylcholine receptors (nAChRs) exist in the ventrolateral medulla, an important site for respiratory control.
EIKI HATORI, SHIGEKI SAKURABA, MASANORI KASHIWAGI, JUNYA KURIBAYASHI, MIKI TSUJITA, YUKI HOSOKAWA, JUNZO TAKEDA, SHUN-ICHI KUWANA   +7 more
doaj  

Alpha7 Helix Plays an Important Role in the Conformational Stability of PTP1B

Journal of Biomolecular Structure and Dynamics, 2011
The C-terminus of Protein Tyrosine Phosphatase 1B (PTP1B) includes an α-helix α7), which forms an allosteric binding site 20 å away from the active site. This helix is specific to PTP1B and its truncation decreases the catalytic activity significantly.
Olmez, Elif Ozkirimli, Alakent, Burak
openaire   +3 more sources

Flavonoids as allosteric modulators of alpha7 nicotinic receptor

, 2017
Fil: Nielsen, Beatriz Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina. Universidad Nacional del Sur.
Nielsen, Beatriz Elizabeth, Bouzat, Cecilia Beatriz   +1 more
openaire   +1 more source

New Pyridyl and Dihydroisoquinoline Alkaloids Isolated from the Chevron Nemertean Amphiporus angulatus

Marine Drugs
Nemertean worms contain toxins that are used to paralyze their prey and to deter potential predators. Hoplonemerteans often contain pyridyl alkaloids like anabaseine that act through nicotinic acetylcholine receptors and crustacean chemoreceptors.
William R. Kem, Ferenc Soti, James R. Rocca, Jodie V. Johnson   +3 more
doaj   +1 more source

Molecular function of alpha7 nicotinic receptors

, 2018
Fil: Bouzat, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur.
openaire   +1 more source

Activation of alpha7 nicotinic and NMDA receptors is necessary for performance in a working memory task

Psychopharmacology, 2020
David Phenis, Sarah A. Vunck, V. Valentini, H. Arias, R. Schwarcz, J. Bruno   +5 more
semanticscholar   +1 more source

Editorial Note: HIV gp120 Induces Mucus Formation in Human Bronchial Epithelial Cells through CXCR4/α7-Nicotinic Acetylcholine Receptors. [PDF]

PLoS One, 2023
PLOS ONE Editors.
europepmc   +1 more source

Pharmacokinetic Limitations on Effects of an Alpha7-Nicotinic Receptor Agonist in Schizophrenia: Randomized Trial with an Extended-Release Formulation

Neuropsychopharmacology, 2018
W. Kem, A. Olincy, L. Johnson, Josette G. Harris, B. Wagner, Robert W. Buchanan, U. Christians, R. Freedman   +7 more
semanticscholar   +1 more source

Serum Levels of Alpha7 Nicotinic Acetylcholine Receptor and Their Association With Cardiovascular Autonomic Function Tests in Healthy Young Adults. [PDF]

Cureus
Karthik S, Elakiya M, Balamurugesan K.
europepmc   +1 more source