Novel Insights for Systemic Inflammation in Sepsis and Hemorrhage
Mediators of Inflammation, 2010 The inflammatory responses in sepsis and hemorrhage remain a major cause of death. Clinically, it is generally accepted that shock in sepsis or hemorrhage differs in its mechanisms.
Bolin Cai, Edwin A. Deitch, Luis Ulloa
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Identification of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25,26-hexol in human urine
Journal of Lipid Research, 1987 A new bile alcohol, 5 beta-cholestanehexol, was identified in the urine of healthy humans as the glucuronide. The bile alcohol glucuronide fraction was isolated by an ion exchange chromatography on piperidinohydroxypropyl Sephadex LH-20.
T Hiraoka +4 more
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Transfection of Mcf-7 Carcinoma Cells with Human Integrin Alpha7 Cdna Promotes Adhesion to Lamini
, 2008 The laminin-binding alpha7beta1 integrin receptor is highly expressed by skeletal and cardiac muscles, and has been suggested to be a crucial molecule during myogenic cell migration and differentiation. Absence of integrin alpha7 subunit contributes to a
YAO, CHUNG-CHEN, 姚宗珍
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Integrin alpha 7 expression in newly diagnosed Egyptian chronic lymphocytic leukemia patients [PDF]
Egyptian Journal of Cancer and Biomedical ResearchBackground: The landscape for chronic lymphocytic leukemia (CLL) has undergone a full makeover since the emergence of effective targeted therapies. Searching for novel biomarkers in CLL patients is critical to improve outcomes in CLL patients. Integrins,
Sarah Nawar, Yasmin samir, Asmaa Mahmoud
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The alpha7 nicotinic acetylcholine receptor: molecular modelling, electrostatics, and energetics.
, 2005 The structure of a homopentameric alpha7 nicotinic acetylcholine receptor is modelled by combining structural information from two sources: the X-ray structure of a water soluble acetylcholine binding protein from Lymnea stagnalis, and the electron ...
Sansom, MS +5 more
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Kinetic properties and open probability of alpha7 nicotinic acetylcholine receptors. [PDF]
, 2014 The alpha7 nicotinic acetylcholine receptor (nAChR) has some peculiar kinetic properties. From the literature of alpha7 nAChR-mediated currents we concluded that experimentally measured kinetic properties reflected properties of the solution exchange ...
Szabó, AK +3 more
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Downregulation of alpha7 nicotinic acetylcholine receptor in two-kidney one-clip hypertensive rats
BMC Cardiovascular Disorders, 2012 Background Inflammation processes are important participants in the pathophysiology of hypertension and cardiovascular diseases. The role of the alpha7 nicotinic acetylcholine receptor (α7nAChR) in inflammation has recently been identified.
Chen Ji-Kuai +5 more
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Small Molecules as Negative Allosteric Modulators of Alpha7 nAChRs [PDF]
, 2012 Alpha7 Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in essential physiological functions and play a role in disorders such as Alzheimer’s disease.
Alwassil, Osama
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Neuronal and Glial α7 Nicotinic Acetylcholine Receptors: Role in Alzheimer’s Disease Pathophysiology
LifeCholinergic projections from the basal forebrain to the cortex and hippocampus play a critical role in cognitive functions, many of which rely on signaling through the alpha7 nicotinic acetylcholine receptor (α7nAChR).
Kerry Rennie
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