Results 61 to 70 of about 5,544 (202)

How Do Unexpected Networks Help Female Entrepreneurs in the Global South Survive in Adverse Contexts? A Case Study of Bangladesh

Gender, Work &Organization, Volume 33, Issue 1, Page 132-163, January 2026.
ABSTRACT This study investigates the role of various unexpected networks in supporting the survival of female‐owned SMEs in the Global South. The research focuses upon Bangladesh, which is a context marked by institutional adversity and postcolonial legacies.
Sharmin Nahar, Mohammed Shamsul Karim, Vania Sena   +2 more
wiley   +1 more source

Characterization of a Bovine Serum Albumin‐Derived Pro‐Cognitive Peptide (bSAPP): An Orally Active Peptide Alleviates Cognitive Decline in HFD‐Fed Mice via CCK Signaling Through the Gut‐Brain Axis

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
The popularity of the Western diet has increased the prevalence of dementia in addition to aging. We found that the digest of bovine serum albumin and a peptide derived from the digest showed an oral pro‐cognitive effect in mice fed a high‐fat diet (HFD). We named the peptide bSAPP (EC50 = 0.01 mg/kg BW). The oral effect of bSAPP was modulated by CCK1R
Biyun Zhang, Mone Ando, Kohei Kawano, Yusaku Iwasaki, Kazuo Inoue, Kousaku Ohinata   +5 more
wiley   +1 more source

Comparative functional expression of nAChR subtypes in rodent DRG neurons

Frontiers in Cellular Neuroscience, 2013
We investigated the functional expression of nicotinic acetylcholine receptors (nAChRs) in heterogeneous populations of dissociated rat and mouse lumbar dorsal root ganglion (DRG) neurons by calcium imaging.
Nathan J. Smith, Arik J. Hone, Tosifa eMemon, Simon eBossi, Thomas E. Smith, J. Michael McIntosh, J. Michael McIntosh, J. Michael McIntosh, Baldomero M. Olivera, Russell W. Teichert   +9 more
doaj   +1 more source

Genome‐wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures

Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION Identifying pleiotropy for blood pressure (BP) and cognitive performance measures may indicate mechanistic links between hypertension and Alzheimer's disease (AD). METHODS We performed a pleiotropy genome‐wide association study (GWAS) for paired measures of systolic, diastolic, pulse, and mean arterial pressure with memory ...
Moonil Kang, Ting Fang Alvin Ang, Sherral A. Devine, Richard Sherva, Shubhabrata Mukherjee, Emily H. Trittschuh, Phoebe Scollard, Michael Lee, Seo‐Eun Choi, Brandon Klinedinst, Connie Nakano, Logan C. Dumitrescu, Timothy J. Hohman, Michael L. Cuccaro, Andrew J. Saykin, Walter A. Kukull, David A. Bennett, Li‐San Wang, Richard P. Mayeux, Jonathan L. Haines, Margaret A. Pericak‐Vance, Gerard D. Schellenberg, Paul K. Crane, Rhoda Au, Kathryn L. Lunetta, Jesse Mez, Lindsay A. Farrer   +26 more
wiley   +1 more source

Copy number variations in healthy subjects. Case study: iPSC line CSSi005-A (3544) production from an individual with variation in 15q13.3 chromosome duplicating gene CHRNA7

Stem Cell Research, 2018
CHRNA7, encoding the neuronal alpha7 nicotinic acetylcholine receptor (a7nAChR), is highly expressed in the brain, particularly in the hippocampus. It is situated in the 15q13.3 chromosome region, frequently associated with a Copy Number Variation (CNV),
Elisa Maria Turco, Ersilia Vinci, Filomena Altieri, Daniela Ferrari, Barbara Torres, Marina Goldoni, Giuseppe Lamorte, Ada Maria Tata, Gianluigi Mazzoccoli, Diana Postorivo, Matteo Della Monica, Laura Bernardini, Angelo Luigi Vescovi, Jessica Rosati   +13 more
doaj   +1 more source

NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin‐Binding Integrins

Advanced Science, Volume 12, Issue 20, May 29, 2025.
Cells transduce the rigidity of the environment into biochemical cues through mechanotransductive cascades that modulate cell behavior. Here, a novel role for the boron transporter NaBC1 is identified as a mechanotransducer involved in regulating cell behavior via specific crosstalk with fibronectin‐binding integrins.
Juan Gonzalez‐Valdivieso, Giuseppe Ciccone, Udesh Dhawan, Tezz Quon, Eva Barcelona‐Estaje, Aleixandre Rodrigo‐Navarro, Rafael R. Castillo, Graeme Milligan, Patricia Rico, Manuel Salmeron‐Sanchez   +9 more
wiley   +1 more source

Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux

OncoTarget, 2015
Activation of the alpha7 nicotinic acetylcholine receptor (α7nAchR) is regulated by prion protein (PrPC) expression and has a neuroprotective effect by modulating autophagic flux.
Jae‐Kyo Jeong, Sang-Youel Park
semanticscholar   +1 more source

Estradiol deficiency as a consequence of aging contributes to the depletion of the satellite cell pool in female mice

Aging Cell, Volume 24, Issue 4, April 2025.
In females, estradiol deficiency is a major environmental factor contributing to the age‐associated effects on satellite cells. To assess cell‐intrinsic versus environmental regulation of satellite cells, we perform two transplantation experiments, Adult or Aged satellite cells transplanted into Adult recipients, and Adult satellite cells transplanted ...
Brian P. Sullivan, Alexie A. Larson, Ahmed S. Shams, Shawna L. McMillin, Mara C. Ebeling, Sydney Peng, Michael Kyba, Dawn A. Lowe   +7 more
wiley   +1 more source

Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins

Marine Drugs, 2022
Nereistoxin (NTX) is a marine toxin isolated from an annelid worm that lives along the coasts of Japan. Its insecticidal properties were discovered decades ago and this stimulated the development of a variety of insecticides such as Cartap that are ...
William R. Kem, Kristin Andrud, Galen Bruno, Hong Xing, Ferenc Soti, Todd T. Talley, Palmer Taylor   +6 more
doaj   +1 more source

Transcriptomic Profiling Reveals 17β‐Estradiol Treatment Represses Ubiquitin‐Proteasomal Mediators in Skeletal Muscle of Ovariectomized Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 1, February 2025.
ABSTRACT Background With a decline of 17β‐estradiol (E2) at menopause, E2 has been implicated in the accompanied loss of skeletal muscle mass and strength. We aimed at characterizing transcriptomic responses of skeletal muscle to E2 in female mice, testing the hypothesis that genes and pathways related to contraction and maintenance of mass are ...
Georgios Kararigas, Mara C. Ebeling, Gengyun Le, Shaojuan Lai, Chunmei Cui, Qinghua Cui, Dawn A. Lowe   +6 more
wiley   +1 more source