Results 61 to 70 of about 4,718 (156)

Further characterisation of the molecular signature of quiescent and activated mouse muscle satellite cells. [PDF]

PLoS ONE, 2009
Satellite cells are the resident stem cells of adult skeletal muscle. To date though, there is a paucity of native markers that can be used to easily identify quiescent satellite cells, with Pax7 probably being the best that is currently available.
Viola F Gnocchi, Robert B White, Yusuke Ono, Juliet A Ellis, Peter S Zammit   +4 more
doaj   +1 more source

A Review of the Role of Paraprobiotics in the Formulation of High‐Protein Ice Cream as an Advanced Functional Food

International Journal of Food Science, Volume 2025, Issue 1, 2025.
Paraprobiotics are nonvital bacteria that have health benefits. Recently, they have been incorporated into dairy products as supplements to probiotics. The advantages of using paraprobiotics mainly include superior resistance to processing conditions, extended shelf‐life, and safer consumption by people with weaker immune systems.
Seyed Ali Issazadeh, Samaneh Hatami, Ivan Salmerón   +2 more
wiley   +1 more source

Unveiling citicoline's mechanisms and clinical relevance in the treatment of neuroinflammatory disorders

The FASEB Journal, Volume 38, Issue 17, September 2024.
Mechanisms of citicoline in treating neuroinflammatory disorders. Abstract Citicoline, a compound produced naturally in small amounts in the human body, assumes a pivotal role in phosphatidylcholine synthesis, a dynamic constituent of membranes of neurons.
Simona Cavalu, Sameh Saber, Asmaa Ramadan, Elsayed A. Elmorsy, Rabab S. Hamad, Mustafa Ahmed Abdel‐Reheim, Mahmoud E. Youssef   +6 more
wiley   +1 more source

Synthesis of C-22, C-23-3H-labeled 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestane.

Journal of Lipid Research, 1985
This report describes an efficient synthesis of C-22, C-23-(3)H-labeled 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane. - Somanathan, R., and S. Krisans. Synthesis of C-22, C-23-(3)H-labeled 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane.
R Somanathan, S Krisans
doaj   +1 more source

GSK3: A potential target and pending issues for treatment of Alzheimer's disease

CNS Neuroscience &Therapeutics, Volume 30, Issue 7, July 2024.
GSK3 signaling in Alzheimer's disease and targeted therapies. Abstract Glycogen synthase kinase‐3 (GSK3), consisting of GSK3α and GSK3β subtypes, is a complex protein kinase that regulates numerous substrates. Research has observed increased GSK3 expression in the brains of Alzheimer's disease (AD) patients and models.
Jiahui Zhao, Mengying Wei, Minsong Guo, Mengyao Wang, Hongxia Niu, Tengfei Xu, Yuan Zhou   +6 more
wiley   +1 more source

Synthesis of the putative metabolites of plant sterols: (24R)- and (24S)-24-methyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrols and 24-ethyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24 xi-tetrol.

Journal of Lipid Research, 1984
This report describes the synthesis of (24R)- and (24S)-24-methyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrols and 24-ethyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24 xi-tetrol starting from cholic acid.
B Dayal, G Salen, G S Tint, A K Batta, S Shefer   +4 more
doaj   +1 more source

Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice

PROTEOMICS, Volume 24, Issue 10, May 2024.
Abstract The alpha7 nicotinic acetylcholine receptor (α7 nAChR; CHRNA7) is expressed in the nervous system and in non‐neuronal tissues. Within the central nervous system, it is involved in various cognitive and sensory processes such as learning, attention, and memory.
Karolina Magdalena Caban, Pia Seßenhausen, Jan Bernard Stöckl, Bastian Popper, Artur Mayerhofer, Thomas Fröhlich   +5 more
wiley   +1 more source

Comprehensive view of macrophage autophagy and its application in cardiovascular diseases

Cell Proliferation, Volume 57, Issue 1, January 2024.
This review systematically describes the role of autophagy in macrophage functions, highlighting the existing evidence in the regulation of inflammation, cell death, metabolism, phagocytosis, and so forth. Meanwhile, we summarize the latest progress of therapeutics targeting macrophage autophagy in cardiovascular diseases, hoping to provide novel ...
Wanqian Pan, Jun Zhang, Lei Zhang, Yue Zhang, Yiyi Song, Lianhua Han, Mingyue Tan, Yunfei Yin, Tianke Yang, Tingbo Jiang, Hongxia Li   +10 more
wiley   +1 more source

The role of alpha-7 nicotinic receptors in food intake behaviors

Frontiers in Psychology, 2014
Nicotine alters appetite and energy expenditure, leading to changes in body weight. While the exact mechanisms underlying these effects are not fully established, both central and peripheral involvement of the alpha-7 nicotinic acetylcholine receptor ...
Kristina L. McFadden, Marc-Andre eCornier, Jason R. Tregellas, Jason R. Tregellas   +3 more
doaj   +1 more source

Voltage- and temperature-dependent allosteric modulation of alpha7 nicotinic receptors by PNU120596

Frontiers in Pharmacology, 2011
Alpha7 nicotinic receptors (a7nAChR) are widely distributed throughout the central nervous system (CNS) and are found at particularly high levels in the hippocampus and cortex.
Fabrio eSitzia, Jon T Brown, Andrew eRandall, John eDunlop   +3 more
doaj   +1 more source