Results 81 to 90 of about 5,544 (202)
Synthesis of C-22, C-23-3H-labeled 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestane.
Journal of Lipid Research, 1985 This report describes an efficient synthesis of C-22, C-23-(3)H-labeled 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane. - Somanathan, R., and S. Krisans. Synthesis of C-22, C-23-(3)H-labeled 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane.
R Somanathan, S Krisans
doaj +1 more source
Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice
PROTEOMICS, Volume 24, Issue 10, May 2024.Abstract The alpha7 nicotinic acetylcholine receptor (α7 nAChR; CHRNA7) is expressed in the nervous system and in non‐neuronal tissues. Within the central nervous system, it is involved in various cognitive and sensory processes such as learning, attention, and memory.
Karolina Magdalena Caban +5 more
wiley +1 more source
Alpha7 nicotinic acetylcholine receptor in macrophage apoptosis and efferocytosis
The FASEB Journal, 2012 The development of atherosclerotic lesions depends on an important inflammatory component mediated mostly by macrophages. Notably, apoptosis of macrophages within the lesion and efficient clearance of apoptotic cells are key factors in lesion progression.
Robert Lee, Guillermo Vazquez
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Journal of Lipid Research, 1984 This report describes the synthesis of (24R)- and (24S)-24-methyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrols and 24-ethyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24 xi-tetrol starting from cholic acid.
B Dayal +4 more
doaj +1 more source
Neuroscience, 2013 Glutamate-induced excitotoxicity is thought to play an important role in several neurodegenerative diseases in the CNS. In this study, neuroprotection against glutamate-induced excitotoxicity was analyzed using acetylcholine, nicotine and the alpha7 ...
K. Iwamoto, David Mata, D. Linn, C. Linn
semanticscholar +1 more source
Comprehensive view of macrophage autophagy and its application in cardiovascular diseases
Cell Proliferation, Volume 57, Issue 1, January 2024.This review systematically describes the role of autophagy in macrophage functions, highlighting the existing evidence in the regulation of inflammation, cell death, metabolism, phagocytosis, and so forth. Meanwhile, we summarize the latest progress of therapeutics targeting macrophage autophagy in cardiovascular diseases, hoping to provide novel ...
Wanqian Pan +10 more
wiley +1 more source
Canadian Journal of Physiology and Pharmacology, 2013 Previous models of disuse have invariably used surgical methods require repetitive plaster casts applications. A method of disuse atrophy that does not require repetitive application is described.
Mohammed A. S. Khan +7 more
semanticscholar +1 more source
The role of alpha-7 nicotinic receptors in food intake behaviors
Frontiers in Psychology, 2014 Nicotine alters appetite and energy expenditure, leading to changes in body weight. While the exact mechanisms underlying these effects are not fully established, both central and peripheral involvement of the alpha-7 nicotinic acetylcholine receptor ...
Kristina L. McFadden +3 more
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Voltage- and temperature-dependent allosteric modulation of alpha7 nicotinic receptors by PNU120596
Frontiers in Pharmacology, 2011 Alpha7 nicotinic receptors (a7nAChR) are widely distributed throughout the central nervous system (CNS) and are found at particularly high levels in the hippocampus and cortex.
Fabrio eSitzia +3 more
doaj +1 more source
Stoichiometry for activation of neuronal alpha7 nicotinic receptors
, 2013 Neuronal α7 nicotinic receptors elicit rapid cation influx in response to acetylcholine (ACh) or its hydrolysis product choline. They contribute to cognition, synaptic plasticity, and neuroprotection and have been implicated in neurodegenerative and neuropsychiatric disorders. α7, however, often localizes distal to sites of nerve-released ACh and binds
Andersen, Natalia Denise +3 more
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