Results 91 to 100 of about 5,544 (202)

Novel Insights for Systemic Inflammation in Sepsis and Hemorrhage

Mediators of Inflammation, 2010
The inflammatory responses in sepsis and hemorrhage remain a major cause of death. Clinically, it is generally accepted that shock in sepsis or hemorrhage differs in its mechanisms.
Bolin Cai, Edwin A. Deitch, Luis Ulloa
doaj   +1 more source

Identification of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,24,25,26-hexol in human urine

Journal of Lipid Research, 1987
A new bile alcohol, 5 beta-cholestanehexol, was identified in the urine of healthy humans as the glucuronide. The bile alcohol glucuronide fraction was isolated by an ion exchange chromatography on piperidinohydroxypropyl Sephadex LH-20.
T Hiraoka, K Kihira, G Kajiyama, T Kuramoto, T Hoshita   +4 more
doaj   +1 more source

Integrin alpha 7 expression in newly diagnosed Egyptian chronic lymphocytic leukemia patients [PDF]

Egyptian Journal of Cancer and Biomedical Research
Background: The landscape for chronic lymphocytic leukemia (CLL) has undergone a full makeover since the emergence of effective targeted therapies. Searching for novel biomarkers in CLL patients is critical to improve outcomes in CLL patients. Integrins,
Sarah Nawar, Yasmin samir, Asmaa Mahmoud
doaj   +1 more source

Downregulation of alpha7 nicotinic acetylcholine receptor in two-kidney one-clip hypertensive rats

BMC Cardiovascular Disorders, 2012
Background Inflammation processes are important participants in the pathophysiology of hypertension and cardiovascular diseases. The role of the alpha7 nicotinic acetylcholine receptor (α7nAChR) in inflammation has recently been identified.
Chen Ji-Kuai, Zhao Ting, Ni Min, Li Dong-Jie, Tao Xia, Shen Fu-Ming   +5 more
doaj   +1 more source

Neuronal and Glial α7 Nicotinic Acetylcholine Receptors: Role in Alzheimer’s Disease Pathophysiology

Life
Cholinergic projections from the basal forebrain to the cortex and hippocampus play a critical role in cognitive functions, many of which rely on signaling through the alpha7 nicotinic acetylcholine receptor (α7nAChR).
Kerry Rennie
doaj   +1 more source

Association of nicotinic acetylcholine receptors with central respiratory control in isolated brainstem-spinal cord preparation of neonatal rats

Biological Research, 2006
Nicotine exposure is a risk factor in several breathing disorders Nicotinic acetylcholine receptors (nAChRs) exist in the ventrolateral medulla, an important site for respiratory control.
EIKI HATORI, SHIGEKI SAKURABA, MASANORI KASHIWAGI, JUNYA KURIBAYASHI, MIKI TSUJITA, YUKI HOSOKAWA, JUNZO TAKEDA, SHUN-ICHI KUWANA   +7 more
doaj  

Synthesis of potential cholelitholytic agents: 3 alpha,7 alpha,12 alpha-trihydroxy-7 beta-methyl-5 beta-cholanoic acid, 3 alpha,7 beta,12 alpha-trihydroxy-7 alpha-methyl-5 beta-cholanoic acid, and 3 alpha,12 alpha-dihydroxy-7 xi-methyl-5 beta-cholanoic acid.

Journal of Lipid Research, 1985
This report describes the chemical synthesis of six new bile acid analogs, namely, 3 alpha,7 alpha,12 alpha-trihydroxy-7 beta-methyl-5 beta-cholanoic acid (7 beta-methyl-cholic acid), 3 alpha,7 beta,12 alpha-trihydroxy-7 alpha-methyl-5 beta-cholanoic ...
S Kuroki, M Une, E H Mosbach
doaj   +1 more source

Flavonoids as allosteric modulators of alpha7 nicotinic receptor

, 2017
Fil: Nielsen, Beatriz Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; Argentina. Universidad Nacional del Sur.
Nielsen, Beatriz Elizabeth, Bouzat, Cecilia Beatriz   +1 more
openaire   +1 more source

New Pyridyl and Dihydroisoquinoline Alkaloids Isolated from the Chevron Nemertean Amphiporus angulatus

Marine Drugs
Nemertean worms contain toxins that are used to paralyze their prey and to deter potential predators. Hoplonemerteans often contain pyridyl alkaloids like anabaseine that act through nicotinic acetylcholine receptors and crustacean chemoreceptors.
William R. Kem, Ferenc Soti, James R. Rocca, Jodie V. Johnson   +3 more
doaj   +1 more source

Molecular function of alpha7 nicotinic receptors

, 2018
Fil: Bouzat, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur.
openaire   +1 more source