Results 41 to 50 of about 566,712 (212)

Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BK-beta-1-subunit leads to progressive hearing loss [PDF]

, 2005
The large conductance voltage- and Ca2+-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of cochlear inner hair cells.
Arntz, Claudia, Braig, Claudia, Engel, Jutta, Hirt, Bernhard, Knipper, Marlies, Knirsch, Martina, Köpschall, Iris, Langer, Patricia, Müller, Marcus, Münkner, Stefan, Pfaff, Imke, Pfister, Markus, Rohbock, Karin, Ruth, Peter, Rüsch, Alfons, Rüttiger, Lukas, Sausbier, Matthias, Winter, Harald, Zimmermann, Ulrike   +18 more
core   +2 more sources

Glycinergic transmission in the mammalian retina

Frontiers in Molecular Neuroscience, 2009
Glycine and γ-aminobutyric acid (GABA) are the major inhibitory neurotransmitters in the retina. Approximately half of the amacrine cells release glycine at their synapses with bipolar, other amacrine, and ganglion cells. Glycinergic amacrine cells
Heinz Wässle, Liane Heinze, Liane Heinze, Elena Ivanova, Elena Ivanova, Sriparna Majumdar, Sriparna Majumdar, Jan Weiss, Jan Weiss, Robert J Harvey, Silke Haverkamp   +10 more
doaj   +1 more source

Novel Insights into Understanding the Molecular Dialogues between Bipolaroxin and the Gα and Gβ Subunits of the Wheat Heterotrimeric G-Protein during Host–Pathogen Interaction

Antioxidants, 2022
Spot blotch disease of wheat, caused by the fungus Bipolaris sorokiniana (Sacc.) Shoem., produces several toxins which interact with the plants and thereby increase the blightening of the wheat leaves, and Bipolaroxin is one of them.
Deepti Malviya, Udai B. Singh, Budheswar Dehury, Prakash Singh, Manoj Kumar, Shailendra Singh, Anurag Chaurasia, Manoj Kumar Yadav, Raja Shankar, Manish Roy, Jai P. Rai, Arup K. Mukherjee, Ishwar Singh Solanki, Arun Kumar, Sunil Kumar, Harsh V. Singh   +15 more
doaj   +1 more source

Expression and Circular Dichroism Studies of the Extracellular Domain of the alpha Subunit of the Nicotinic Acetylcholine Receptor [PDF]

, 1997
To provide material suitable for structural studies of the nicotinic acetylcholine receptor, we have expressed and purified the NH2-terminal extracellular domain of the mouse muscle alpha subunit.
Bjorkman, Pamela J., Dougherty, Dennis A., Lester, Henry A., West, Anthony P., Jr.   +3 more
core  

Nucleotide sequence of the luxA gene of Vibrio harveyi and the complete amino acid sequence of the alpha subunit of bacterial luciferase [PDF]

, 1985
The nucleotide sequence of the 1.85-kilobase EcoRI fragment from Vibrio harveyi that was cloned using a mixed-sequence synthetic oligonucleotide probe (Cohn, D. H., Ogden, R. C., Abelson, J. N., Baldwin, T. O., Nealson, K. H., Simon, M.
Baldwin, Thomas O., Bonam, Duane, Cohn, Daniel H., Mileham, Alan J., Nealson, Kenneth H., Rausch, Steven K., Simon, Melvin I.   +6 more
core  

Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160

Molecular Therapy: Nucleic Acids, 2017
Laminin-111 protein complex links the extracellular matrix to integrin α7β1 in sarcolemma, thus replacing in dystrophic muscles links normally insured by the dystrophin complex.
Arnaud Perrin, Joël Rousseau, Jacques P. Tremblay   +2 more
doaj   +1 more source

Decreased soluble guanylate cyclase contributes to cardiac dysfunction induced by chronic doxorubicin treatment in mice [PDF]

, 2017
Aims: The use of doxorubicin, a potent chemotherapeutic agent, is limited by cardiotoxicity. We tested the hypothesis that decreased soluble guanylate cyclase (sGC) enzyme activity contributes to the development of doxorubicin-induced cardiotoxicity ...
Allen, Kaitlin, Bartunek, Jozef, Beerens, Manu, Bloch, Donald B, Bloch, Kenneth D, Brouckaert, Peter, Buys, Emmanuel S, Caluwe, Ellen, Gillijns, Hilde, Janssens, Stefan P, Nathan, Daniel I, Scherrer-Crosbie, Marielle, Swinnen, Melissa, Tainsh, Robert E, Vandenwijngaert, Sara, Walravens, Ann-Sophie   +15 more
core   +1 more source

Expression of a beta 1-related integrin by oligodendroglia in primary culture: evidence for a functional role in myelination. [PDF]

, 1994
We have investigated the expression of integrins by rat oligodendroglia grown in primary culture and the functional role of these proteins in myelinogenesis.
Malek-Hedayat, S, Rome, LH
core  

Retinoic acid regulates the ubiquitin–proteasome system in a middle cerebral artery occlusion animal model

Laboratory Animal Research, 2022
Background Retinoic acid is a major metabolite of vitamin A and exerts beneficial effects including anti-oxidant and anti-inflammatory activities in neurons.
Ju-Bin Kang, Murad-Ali Shah, Dong-Ju Park, Phil-Ok Koh   +3 more
doaj   +1 more source

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire [PDF]

, 2012
Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve
A. Lucas, A. M. English, A. Sette, A. Wriston, B. J. Grant, B. Peters, C. A. F. de Oliveira, C. Oseroff, Cahalan, Chessman, Chung, D. A. Ostrov, D. F. Hunt, Day, E. Phillips, Faletto, Friesner, H. M. Grey, H. Mei, Harndahl, J. Jakoncic, J. Shabanowitz, J. Sidney, Ko, L. Shi, L. Yang, Lavergne, M. Harndahl, Mallal, Martin, Melroy, Phillips, Pichler, Rudolph, S. Buus, S. Lu, S. Mallal, S. Southwood, Shastri, Shimizu, Sidney, Sidney, Tenzer, Udeshi, Y. A. Pompeu, Yang, Yang, Yewdell   +47 more
core   +4 more sources