Results 31 to 40 of about 354,799 (167)

Evaluation of the Phosphoproteome of Mouse Alpha 4/Beta 2-Containing Nicotinic Acetylcholine Receptors In Vitro and In Vivo

open access: yesProteomes, 2018
Activation of nicotinic acetylcholine receptors containing α4 and β2 subunits (α4/β2* nAChRs) in the mammalian brain is necessary for nicotine reinforcement and addiction. We previously identified interactions between α4/β
Megan B. Miller   +4 more
doaj   +1 more source

Glycinergic transmission in the mammalian retina

open access: yesFrontiers in Molecular Neuroscience, 2009
Glycine and γ-aminobutyric acid (GABA) are the major inhibitory neurotransmitters in the retina. Approximately half of the amacrine cells release glycine at their synapses with bipolar, other amacrine, and ganglion cells. Glycinergic amacrine cells
Heinz Wässle   +10 more
doaj   +1 more source

Novel Insights into Understanding the Molecular Dialogues between Bipolaroxin and the Gα and Gβ Subunits of the Wheat Heterotrimeric G-Protein during Host–Pathogen Interaction

open access: yesAntioxidants, 2022
Spot blotch disease of wheat, caused by the fungus Bipolaris sorokiniana (Sacc.) Shoem., produces several toxins which interact with the plants and thereby increase the blightening of the wheat leaves, and Bipolaroxin is one of them.
Deepti Malviya   +15 more
doaj   +1 more source

Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160

open access: yesMolecular Therapy: Nucleic Acids, 2017
Laminin-111 protein complex links the extracellular matrix to integrin α7β1 in sarcolemma, thus replacing in dystrophic muscles links normally insured by the dystrophin complex.
Arnaud Perrin   +2 more
doaj   +1 more source

Retinoic acid regulates the ubiquitin–proteasome system in a middle cerebral artery occlusion animal model

open access: yesLaboratory Animal Research, 2022
Background Retinoic acid is a major metabolite of vitamin A and exerts beneficial effects including anti-oxidant and anti-inflammatory activities in neurons.
Ju-Bin Kang   +3 more
doaj   +1 more source

A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications. [PDF]

open access: yesPLoS ONE, 2008
In vertebrates, non-lens betagamma-crystallins are widely expressed in various tissues, but their functions are unknown. The molecular mechanisms of trefoil factors, initiators of mucosal healing and being greatly involved in tumorigenesis, have remained
Shu-Bai Liu   +6 more
doaj   +1 more source

Transcriptional regulators of Na, K-ATPase subunits

open access: yesFrontiers in Cell and Developmental Biology, 2015
The Na,K-ATPase classically serves as an ion pump creating an electrochemical gradient across the plasma membrane that is essential for transepithelial transport, nutrient uptake and membrane potential.
Zhiqin eLi, Sigrid A Langhans
doaj   +1 more source

The thermal structural transition of alpha-crystallin modulates subunit interactions and increases protein solubility. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Alpha crystallin is an oligomer composed of two types of subunits, alpha-A and alpha-B crystallin, and is the major constituent of human lens. The temperature induced condensation of alpha-crystallin, the main cause for eye lens opacification
Giuseppe Maulucci   +3 more
doaj   +1 more source

The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.

open access: yesPLoS Genetics, 2010
Although acetylated alpha-tubulin is known to be a marker of stable microtubules in neurons, precise factors that regulate alpha-tubulin acetylation are, to date, largely unknown.
Jachen A Solinger   +9 more
doaj   +1 more source

Immunoaffinity purification of GABAA receptor alpha-subunit iso-oligomers. Demonstration of receptor populations containing alpha 1 alpha 2, alpha 1 alpha 3, and alpha 2 alpha 3 subunit pairs.

open access: yesJournal of Biological Chemistry, 1991
Novel methods for the isolation of gamma-aminobutyric acidA (GABAA) receptor alpha subunit iso-oligomers have been developed. Thus, populations of GABAA receptors containing the GABAA receptor alpha 1 subunit, the alpha 2 subunit, and the alpha 3 subunit have been purified from sodium deoxycholate extracts of bovine cerebral cortex with the retention ...
M J, Duggan, S, Pollard, F A, Stephenson
openaire   +2 more sources

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