Results 11 to 20 of about 354,799 (167)

The impact of spike mutated variants of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit recombinant vaccines

open access: yesBrazilian Journal of Infectious Diseases, 2021
Since the first described human infection with SARS-CoV-2 in December of 2019 many subunit protein vaccines have been proposed for use in humans. Subunit vaccines use one or more antigens suitable for eliciting a robust immune response.
Mehrdad Mohammadi   +2 more
doaj   +1 more source

Transcriptome sequencing identifies genes associated with invasion of ovarian cancer

open access: yesJournal of International Medical Research, 2020
Objective To identify key genes in ovarian cancer using transcriptome sequencing in two cell lines: MCV152 (benign ovarian epithelial tumour) and SKOV-3 (ovarian serous carcinoma).
Xiandong Peng, Min Yu, Jiazhou Chen
doaj   +1 more source

Expression of the calcium-activated potassium channel in upper and lower segment human myometrium during pregnancy and parturition

open access: yesReproductive Biology and Endocrinology, 2009
Background Large conductance calcium-activated potassium channel (BKCa) plays an important role in the control of uterine contractility during pregnancy.
Zhang Lanmei   +3 more
doaj   +1 more source

Cloning and Characterization of Protein Prenyltransferase Alpha Subunit in Rice

open access: yesRice Science, 2021
Protein prenylation plays a crucial role in plant development and stress response. We report the function of prenyltransferase α-subunit in rice. Protein-protein interactions showed that the farnesyl- transferase (OsPFT)/geranylgeranyltransferase-I ...
Wang Tao   +4 more
doaj   +1 more source

Cloning of a novel inhibin alpha cDNA from rhesus monkey testis

open access: yesReproductive Biology and Endocrinology, 2004
Background Inhibins are dimeric gonadal protein hormones that negatively regulate pituitary FSH synthesis and secretion. Inhibin B is produced by testicular Sertoli cells and is the primary circulating form of inhibin in most adult male mammals.
Woodruff Teresa K   +2 more
doaj   +1 more source

Structure-function relations in oxaloacetate decarboxylase complex. Fluorescence and infrared approaches to monitor oxomalonate and Na(+) binding effect. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND:Oxaloacetate decarboxylase (OAD) is a member of the Na(+) transport decarboxylase enzyme family found exclusively in anaerobic bacteria. OAD of Vibrio cholerae catalyses a key step in citrate fermentation, converting the chemical energy of the
Thierry Granjon   +6 more
doaj   +1 more source

Generation of a PPP1CA knockout human pluripotent stem cell line via CRISPR/Cas9

open access: yesStem Cell Research, 2023
The Protein phosphatase 1 catalytic subunit alpha (PPP1CA) is a alpha subunit of the PP1 complex, which known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein ...
Xiaoman Wang   +3 more
doaj   +1 more source

Analysis of Maxi-K alpha subunit splice variants in human myometrium

open access: yesReproductive Biology and Endocrinology, 2004
Background Large-conductance, calcium-activated potassium (Maxi-K) channels are implicated in the modulation of human uterine contractions and myometrial Ca2+ homeostasis.
Morrison John J   +2 more
doaj   +1 more source

KCNE regulation of K+ channel trafficking – a Sisyphean task?

open access: yesFrontiers in Physiology, 2012
Voltage-gated potassium (Kv) channels shape the action potentials of excitable cells and regulate membrane potential and ion homeostasis in excitable and nonexcitable cells.
Vikram Anmol Kanda   +2 more
doaj   +1 more source

Phylogenomic analyses reveal the evolutionary origin of the inhibin alpha-subunit, a unique TGFbeta superfamily antagonist. [PDF]

open access: yesPLoS ONE, 2010
Transforming growth factor-beta (TGFbeta) homologues form a diverse superfamily that arose early in animal evolution and control cellular function through membrane-spanning, conserved serine-threonine kinases (RII and RI receptors).
Jie Zhu   +10 more
doaj   +1 more source

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