Results 241 to 250 of about 67,783 (305)

Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations [PDF]

, 2016
et al,, Urano, Fumihiko
core   +1 more source

Disturbing dreams and dementia incidence across diverse cohort studies: A COSMIC collaboration study

Psychiatry and Clinical Neurosciences, EarlyView.
Aim Distressing dreams were previously reported to predict future all‐cause dementia among predominantly white US participants aged 79–89 years, particularly in men. We investigated whether disturbing dreams (nightmares and bad dreams) were associated with all‐cause and Alzheimer dementia (AD) among individuals aged 60–89 years from diverse ...
Darren M. Lipnicki, Ashleigh S. Vella, Erico Castro‐Costa, Sergio Luis Blay, Maria Fernanda Lima‐Costa, Karen Ritchie, Elena Rolandi, Annalisa Davin, Michele Rossi, Ki Woong Kim, Ji Won Han, Dae Jong Oh, Ding Ding, Qianhua Zhao, Xiaowen Zhou, Yen‐Ching Chen, Jen‐Hau Chen, Perminder S. Sachdev, for Cohort Studies of Memory in an International Consortium (COSMIC)   +18 more
wiley   +1 more source

The extent of alpha-synuclein aggregate accumulation in neurons varies depending on the type of neurotransmitter they release. [PDF]

Sci Rep
Kameda H, Okamoto S, Ogasawara K, Okuzumi A, Hattori N, Hioki H, Koike M.   +6 more
europepmc   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Alpha-synuclein seeding activity in postmortem tissues from patients with diffuse and isolated Lewy bodies. [PDF]

Acta Neuropathol Commun
Baranová S, Matěj R, Soukup J, Dušek P, Holada K.   +4 more
europepmc   +1 more source

Physiology, pathology and therapeutic potential of microglial triggering receptor expressed on myeloid cells 2 signalling: A narrative update

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong, Libin Shen, Daqing Ma, Jinchao Hou   +3 more
wiley   +1 more source

Alpha-synuclein fibrils induce budding of mitochondrial-derived vesicles

Braun T, Tiberi C, Reber V, Ghosh D, Riek R, Serdiuk T.   +5 more
europepmc   +1 more source

Evaluation of an antibody panel for alpha-synuclein detection in FFPE rectal biopsies in Parkinson's disease. [PDF]

IBRO Neurosci Rep
Schröder K, Kintrup C, Kulcsárová K, Heinzel S, Kluge A, Wedel T, Böttner M, Lucius R, Pendziwiat M, Schoch S, Ellrichmann M, Berg D, Schaeffer E, Cossais F.   +13 more
europepmc   +1 more source