Results 131 to 140 of about 12,278 (197)

Alternative cell line for the isolation of salmonid alphavirus-1 [PDF]

, 2009
Salmonid alphavirus (SAV) has recently become an economically important pathogen in salmonid aquaculture in Europe. Subtype SAV-1 causes salmon pancreas disease (SPD) in Atlantic salmon in Scotland and Ireland, and was first isolated on Chinook salmon ...
Adams, Alexandra, Richards, Randolph, Thompson, Kimberly, Herath, Tharangani, Costa, Janina Z   +4 more
core  

The Role of the Deubiquitylase UCHL3 During Alphavirus Infection [PDF]

Alphaviruses are positive-sense RNA viruses from the family Togaviridae. These viruses rely on arthropod vectors, such as mosquitos, to replicate before transmission to vertebrates. There are several medically important viruses in this group, including Chikungunya virus (CHIKV) which, since 2004, has caused large number of epidemics that have infected ...
openaire   +1 more source

DHHC enzymes in alphavirus glycoprotein acylation: A target for broad-spectrum antiviral therapy

Cell Reports
Summary: Alphaviruses are mosquito-transmitted viruses that cause severe zoonotic diseases. Their envelope glycoproteins, E1 and E2, undergo cysteine acylation, a process critical for virus infection but previously undefined mechanistically.
Xiaoling Li, Chaoyun Han, Wanjie Song, Zhiwen Jiang, Yunbiao Lu, Sainan Wang, Jie Chen, Yu Deng, Andres Merits, Wan-Ting He, Shuo Su, Michael Veit   +11 more
doaj   +1 more source

A storm is born: immune activation and pathogenesis in arthritogenic alphavirus infections

Current Opinion in Virology
Arthritogenic alphaviruses, including chikungunya (CHIKV), Ross River, and Mayaro viruses, are emerging global viruses responsible for causing arthralgia and chronic arthritis. Following mosquito-borne transmission, they quickly initiate infection in the skin, including in resident immune cells, and disseminate systemically into musculoskeletal tissues.
Wesley Freppel, Yong Qian Koo, Lara J Herrero   +2 more
openaire   +2 more sources

Emerg Infect Dis [PDF]

Everglades virus (EVEV), an alphavirus in the Venezuelan equine encephalitis (VEE) serocomplex, circulates among rodents and vector mosquitoes and infects humans, causing a febrile disease sometimes accompanied by neurologic manifestations.

core  

Mayaro Virus Infection in Traveler Returning from Amazon Basin, Northern Peru

Emerging Infectious Diseases, 2012
Andreas Neumayr, Martin Gabriel, Jasmin Fritz, Stephan Günther, Christoph Hatz, Jonas Schmidt-Chanasit, Johannes Blum   +6 more
doaj   +1 more source

High-Throughput Fluorescence-Based Screen Identifies the Neuronal MicroRNA miR-124 as a Positive Regulator of Alphavirus Infection. [PDF]

J Virol, 2020
López P, Girardi E, Mounce BC, Weiss A, Chane-Woon-Ming B, Messmer M, Kaukinen P, Kopp A, Bortolamiol-Becet D, Fendri A, Vignuzzi M, Brino L, Pfeffer S.   +12 more
europepmc   +1 more source

Neurotropic alphavirus infection induces PARP-1 hyperactivation-mediated energy collapse in motor neurons. [PDF]

J Virol
Williams RE, Pieterse L, Patel SS, McLaren MW, Elrick MJ, Griffin DE.   +5 more
europepmc   +1 more source

Bat Dicer antiviral role and subcellular localization differ upon alphavirus infection in two distinct species. [PDF]

PLoS Pathog
Gaucherand L, Marie H, Cremaschi J, Pfeffer S.   +3 more
europepmc   +1 more source

Broad spectrum antiviral BDGR-164 provides protection against lethal neurotropic alphavirus infection in mice. [PDF]

Antiviral Res
Williams EP, Xue Y, Yang D, Lee J, Kim E, Ponce-Flores A, Zalduondo L, Cao X, Chung D, Golden JE, Meibohm B, Fitzpatrick EA, Weaver SC, Jonsson CB.   +13 more
europepmc   +1 more source