Results 121 to 130 of about 15,250 (221)

Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion. [PDF]

, 2016
The host responds to virus infection by activating type I interferon (IFN) signaling leading to expression of IFN-stimulated genes (ISGs). Dysregulation of the IFN response results in inflammatory diseases and chronic infections.
Bozzacco, Leonia, Breton, Gaëlle, Hoffmann, Hans-Heinrich, Li, Melody MH, Loschko, Jakob, MacDonald, Margaret R, Monette, Sébastien, Rice, Charles M, Xiao, Jing W   +8 more
core  

Viruses and the cellular RNA decay machinery. [PDF]

, 2010
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core   +1 more source

[Morphological study of a mixed alphavirus infection].

Voprosy virusologii, 1982
In combined paired cultivation of 8 Venezuelan equine encephalomyelitis virus, multiploid virions formed in 17.8% of cases. Five clones with this effect were used in mixed infections with clones of Semliki Forest and Sindbis viruses. In these infections changes in virions of the virus progeny were observed in 20% and 16.6%, respectively.
B V, Gushchin, Ia Ia, Tsilinskiĭ, E F, Karpova, E A, Gushchina, S M, Klimenko   +4 more
openaire   +1 more source

Semliki Forest viiruse replikaasivalgu nsP1 uurimine [PDF]

, 2013
Väitekirja elektrooniline versioon ei sisalda publikatsioone.Semliki Forest viirus kuulub alfaviiruste perekonda sugukonnas Togaviridae. Alfaviirused on olulised patogeenid ning põhjustavad erinevaid vaevusi nii loomadele kui ka inimestele.
Karo-Astover, Liis
core  

Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil. [PDF]

, 2019
Zika virus infection is associated with the development of Guillain-Barré syndrome (GBS), a neurological autoimmune disorder caused by immune recognition of gangliosides and other components at nerve membranes.
Alcantara, Luiz Carlos Junior, de Siqueira, Isadora Cristina, do Rosário, Mateus Santana, Ernst, Joel D, Mota, Sabrina, Pereira de Jesus, Pedro Antônio, Rivera-Correa, Juan, Rodriguez, Ana   +7 more
core   +1 more source

Alphavirus Infection of the CNS: Entry, Dissemination, and Neurodegeneration

European Journal of Molecular & Clinical Medicine, 2015
Alphaviruses most often associated with neuroinvasive disease are limited to the Americas and include strains of EEEV, VEEV, and WEEV. The process of alphavirus entry into the CNS of infected vertebrates following challenge is not well-understood. It is thought that virus entry into the CNS depends on the inoculation route.
Phillips AT, Rico AB, Aboellail TA, Olson KE   +3 more
openaire   +1 more source

Endemic and Epidemic Human Alphavirus Infections in Eastern Panama: An Analysis of Population-Based Cross-Sectional Surveys. [PDF]

Am J Trop Med Hyg, 2020
Carrera JP, Cucunubá ZM, Neira K, Lambert B, Pittí Y, Liscano J, Garzón JL, Beltran D, Collado-Mariscal L, Saenz L, Sosa N, Rodriguez-Guzman LD, González P, Lescano AG, Pereyra-Elías R, Valderrama A, Weaver SC, Vittor AY, Armién B, Pascale JM, Donnelly CA.   +20 more
europepmc   +1 more source

Venezuelan equine encephalitis virus non-structural protein 3 dictates superinfection exclusion in mammalian cells

npj Viruses
Superinfection exclusion (SIE) prevents secondary infections of already infected cells. Arthritogenic alphaviruses induce SIE via early proteolytical cleavage of replicase precursor by non-structural protein 2 (nsP2).
Tessy A. H. Hick, Taja Zotler, Davita Bosveld, Corinne Geertsema, Monique M. van Oers, Gorben P. Pijlman   +5 more
doaj   +1 more source

Unraveling the complex interplay: immunopathology and immune evasion strategies of alphaviruses with emphasis on neurological implications

Frontiers in Cellular and Infection Microbiology
Arthritogenic alphaviruses pose a significant public health concern due to their ability to cause joint inflammation, with emerging evidence of potential neurological consequences.
Raquel de Oliveira Souza, José Wandilson Barboza Duarte Júnior, Victória Simões Della Casa, Daniela Santoro Rosa, Laurent Renia, Laurent Renia, Laurent Renia, Carla Claser, Carla Claser   +8 more
doaj   +1 more source

Baseline Seroprevalence of Arboviruses in Liberia Using a Multiplex IgG Immunoassay

Tropical Medicine and Infectious Disease
Insect-borne viruses may account for a significant proportion of non-malaria and non-bacterial febrile illnesses in Liberia. Although the presence of many arthropod vectors has been documented, the collective burden of arbovirus infections and baseline ...
Albert To, Varney M. Kamara, Davidetta M. Tekah, Mohammed A. Jalloh, Salematu B. Kamara, Teri Ann S. Wong, Aquena H. Ball, Ludwig I. Mayerlen, Kyle M. Ishikawa, Hyeong Jun Ahn, Bode Shobayo, Julius Teahton, Brien K. Haun, Wei-Kung Wang, John M. Berestecky, Vivek R. Nerurkar, Peter S. Humphrey, Axel T. Lehrer   +17 more
doaj   +1 more source