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RNA Capping, Replication Complex Assembly, and Translational Regulation in Chikungunya Virus: Molecular Mechanisms and Antiviral Opportunities. [PDF]
Patil RR, Pawar S, Patil S, Hinge DD.
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The search for antivirals to treat alphavirus infections
Alphaviruses are a group of viruses responsible for a variety of emerging and re-emerging human diseases. Although they do not generally cause life-threatening illnesses, they can lead to debilitating and chronic conditions.
Marcella Bassetto, Andrea Brancale
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Alphavirus infections in salmonids – a review
Journal of Fish Diseases, 2007AbstractThe first alphavirus to be isolated from fish was recorded in 1995 with the isolation of salmon pancreas disease virus from Atlantic salmon, Salmo salar L., in Ireland. Subsequently, the closely related sleeping disease virus was isolated from rainbow trout, Oncorhynchus mykiss (Walbaum), in France.
M F, McLoughlin, D A, Graham
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Arthritis Associated with Alphavirus Infections: Chikungunya
2019Since 2004, the epidemic of alphavirus, mainly chikungunya viral (CHIKV) infection, has spread throughout the world and will continue to produce outbreaks due to viral mutations and the spread caused by travelers visiting endemic areas.
Jara Lj +1 more
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Arthritis Associated with Alphavirus Infections: Dengue and Zika
2019Dengue virus (DENV) and Zika virus (ZIKV) are a cause of significant morbidity and mortality worldwide within specific regions of the world where they are endemic and susceptible to the occurrence of epidemics. The interaction between these viruses and other host factors (especially the immunocompetence) seems to influence the expression and severity ...
Sergio Miguel Angel Toloza +1 more
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Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies [PDF]
Alphaviruses are re-emerging vector-born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there ...
Suresh Mahalingam
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Host responses to alphavirus infection
Immunological Reviews, 2008Summary: Members of the Alphavirus genus are classified into New World and Old World groups based upon their disease characteristics and primary areas of endemicity. The two groups exhibit noteworthy differences in pathogenesis during human infection, with Old World viruses primarily causing febrile and arthritogenic diseases and the New World viruses
Kate D, Ryman, William B, Klimstra
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