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Alphavirus Infection in Cultured Tissue Cells
1991Mosquitoes have been recognized since the early 1900s as vectors of a variety of pathogenic viruses that have plagued humans and domestic animals for centuries. Thorough understanding of the life cycles of these pathogens is essential for developing methods for their control.
Mary L. Miller, Dennis T. Brown
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Defective particles in alphavirus infections.
Medical biology, 1976This article summarizes our studies with defective-interfering particles of Sindbis virus obtained by high multiplicity passaging of the virus in BHK cells. Cells infected with these defective passages accumulate a species of RNA (20S) at the expense of 26S RNA--the mRNA coding for the viral structural proteins.
S, Schlesinger, B, Weiss, D, Dohner
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First laboratory confirmation of salmonid alphavirus infection in Italy and Spain
Journal of Fish Diseases, 20071 Veterinary Sciences Division, Agri-Food and Biosciences Institute of Northern Ireland, Stormont, Belfast, Northern Ireland 2 Department of Veterinary Science, Queen s University of Belfast, Veterinary Sciences Division, Stormont, Belfast, Northern Ireland 3 Istituto Zooprofilattico delle Venezie, Legnaro, Padova, Italy 4 Aquatic Veterinary Services ...
D A, Graham +8 more
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Murine Models of Alphavirus Infection to Study the Immunopathogenesis of Pain
Alphaviruses, such as Chikungunya and Mayaro, are emerging arthropod-borne pathogens that particularly affect developing countries. Alphavirus infection has great clinical relevance and must be identified and treated properly, as the disease caused by these viruses has a characteristic chronic phase with joint pain that can last for several months or ...Victor R M, Costa +9 more
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Arthritis Associated with Alphavirus Infections: Dengue and Zika
2019Dengue virus (DENV) and Zika virus (ZIKV) are a cause of significant morbidity and mortality worldwide within specific regions of the world where they are endemic and susceptible to the occurrence of epidemics. The interaction between these viruses and other host factors (especially the immunocompetence) seems to influence the expression and severity ...
Sergio Miguel Angel Toloza +1 more
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Age-dependent susceptibility to fatal encephalitis: alphavirus infection of neurons
1994Sindbis virus encephalitis in mice provides a model for studying age-dependent susceptibility to acute viral encephalitis. The AR339 strain of SV causes fatal encephalitis in newborn mice, but weanling mice recover uneventfully. Increased virulence for older mice is associated with a single amino acid change from Gln to His at position 55 of the E2 ...
D E, Griffin +4 more
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Regulation of alphavirus infection by cellular microRNAs
Étude du mécanisme de régulation des alphavirus par les microARN cellulaires : rôle de miR-124 dans l'infection par les alphavirus Les microARN (miARN) sont des petits ARN non-codants qui agissent comme des régulateurs post- transcriptionnels de l’expression de gènes en ciblant les ARN messagers. Ils sont impliqués dans la régulationopenaire +1 more source
A molecular understanding of alphavirus entry and antibody protection
Nature Reviews Microbiology, 2022Arthur S Kim, Michael S Diamond
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