Results 41 to 50 of about 3,505,696 (258)
FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis [PDF]
, 2017 The FUS gene has been linked to amyotrophic lateral sclerosis (ALS). FUS is a ubiquitous RNA-binding protein, and the mechanisms leading to selective motoneuron loss downstream of ALS-linked mutations are largely unknown.
Alfano, Vincenzo +7 more
core +2 more sources
AL TAGHAYYURĀT AL DILĀLIYYAH FÎ AL KALIMĀT AL SUNDĀWIYYAH AL MUQTARIDHAH MIN AL QURĀN AL KARÎM WA AL ISTIFĀDAH MINHĀ FÎ TA’LÎM AL LUGHAH AL ‘ARABIYYAH [PDF]
Al Mi'yar: Jurnal Ilmiah Pembelajaran Bahasa Arab dan Kebahasaaraban, 2020 Islam datang membawa kontribusi besar untuk membangun masyarakat Sunda. Diantaranya, pengayaan kata serapan dari Al quran. hal ini adalah bukti adanya hubungan yang kuat sejak masuknya Islam ke tanah Sunda. Penelitian ini bertujuan untuk mengetahui perubahan-perubahan semantis kata-kata serapan Sunda dari Alquran, dan juga bertujuan mengetahui metode ...
Rudi Irawan +2 more
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A High-throughput qPCR-based Method to Genotype the SOD1G93A Mouse Model for Relative Copy Number
Bio-Protocol, 2019 The most commonly used mouse model in ALS preclinical research expresses multiple copies of the human SOD1 (G93A) transgene. During the course of breeding, successive generations of mice can lose copies of the transgene. Because shorter lifespan of these
Valerie Tassinari, Fernando Vieira
doaj +1 more source
The Self-Definition of Hellenic Identity through the Culture of Mousikē [PDF]
, 2019 Altgriechische Quellen sind voll von Verweisen auf die Musik von Völkern, die nicht griechisch sind und deshalb stereotyp als ,Barbaren‘ bezeichnet werden.
Rocconi, Eleonora
core +1 more source
Al Mi'yar: Jurnal Ilmiah Pembelajaran Bahasa Arab dan Kebahasaaraban, 2023 <p style="text-align: justify;"><em>Loan words were foreign words used by a particular language to fill a linguistic gap, multiplying borrowed words in the target language. In addition to borrowing words from Sanskrit, Spanish, Portuguese, Dutch, and English, the Indonesian language also use many words from Arabic. As part of this research,
Ghazali Abdul Rahman Kastella +3 more
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Al-‘Unfu fî al-Tarbiyah min Mandzûr al-Tashrî’ al-Indûnîsî wa al-Sharî’ah al-Islâmiyah
AL-IHKAM: Jurnal Hukum & Pranata Sosial, 2022 Violence on children has become a big unsolvable problem in Indonesian education. In fact, the government has ratified some Laws to protect them from any form of violence. Likely, Islam as the mostly followed religion in the country does the same through its mission called rahmatan li al-alamin or blessing for all. This research relies on a question on
Mohammad Kosim +2 more
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Al-Maujah al-Islāmiyyah al-Ukhrā: Al-Istisyrāq wa al-Dirāsāt al-Islāmiyyah al-Mu‘āṣirah
Al-Jami'ah: Journal of Islamic Studies, 2007 This article explores the mapping of the development of Islamic studies from its inception to the present, which consists of three waves. The first wave was the study of Islam by internal Muslims themselves. This period lacks comprehensive factors to categorize as an academic study.
openaire +1 more source
3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes
The FEBS Journal, EarlyView.Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut +2 more
wiley +1 more source
Nature Communications, 2021 Organoids have improved disease modeling. Here, the authors generate human sensorimotor organoids derived from hiPSCs of individuals with ALS. These organoids contain skeletal muscle, sensory and motor neurons as well as astrocytes, microglia, and ...
João D. Pereira +9 more
doaj +1 more source
Promoting Independence Through Effective Interventions For Adults With ALS [PDF]
, 2020 PICO Question What are effective occupational therapy interventions for adults with ALS to improve participation in ADLs/IADLs? Objectives Define amyotrophic lateral sclerosis (ALS) and recognize the prevalence Identify and describe evidence-based ...
Gluchowski, OTS, Renee +4 more
core +1 more source