Results 71 to 80 of about 21,134 (240)

Preeclampsia prediction with blood pressure measurements: A global external validation of the ALSPAC models.

Pregnancy Hypertension, 2022
OBJECTIVE The prediction of preeclampsia in pregnancy has resulted in a plethora of prognostic models. Yet, very few make it past the development stage and most fail to influence clinical practice.
Annelien C de Kat, J. Hirst, M. Woodward, F. Barros, H. Barsosio, J. Berkley, M. Carvalho, L. Cheikh Ismail, R. McGready, S. Norris, F. Nosten, E. Ohuma, Chrystelle O. O. Tshivuila-Matala, W. Stones, E. Staines Urias, Maria Clara Restrepo-Mendez, A. Lambert, S. Munim, A. Winsey, A. Papageorghiou, Z. Bhutta, J. Villar, S. Kennedy, S. Peters   +23 more
semanticscholar   +1 more source

Prenatal anxiety, breastfeeding and child growth and puberty: linking evolutionary models with human cohort studies

Annals of Human Biology, 2020
Background: Stress experienced by mothers during pregnancy can have both immediate and long-term effects on child development, potentially mediated by breastfeeding.
Sinead English, India Wright, Verity Ashburn, Gemma Ford, Doretta Caramaschi   +4 more
doaj   +1 more source

Genome-wide association study identifies common and low-frequency variants at the AMHgene locus that strongly predict serum AMH levels in males [PDF]

, 2016
Anti-Müllerian hormone (AMH) is an essential messenger of sexual differentiation in the foetus and is an emerging biomarker of postnatal reproductive function in females.
Day, Felix R., Lawlor, Debbie A., McMahon, George, Nelson, Scott M., Perry, John R.B., Ring, Susan M.   +5 more
core   +1 more source

Determinants of Intima-Media Thickness in the Young: The ALSPAC Study. [PDF]

JACC. Cardiovascular imaging, 2019
This study characterized the determinants of carotid intima-media thickness (cIMT) in a large (n > 4,000) longitudinal cohort of healthy young people age 9 to 21 years.Greater cIMT is commonly used in the young as a marker of subclinical atherosclerosis, but its evolution at this age is still poorly understood.Associations between cardiovascular risk ...
Chiesa, Scott T., Charakida, Marietta, Georgiopoulos, Georgios, Dangardt, Frida, Wade, Kaitlin H., Rapala, Alicja, Bhowruth, Devina J., Nguyen, Helen C., Muthurangu, Vivek, Shroff, Rukshana, Davey Smith, George, Lawlor, Debbie A., Sattar, Naveed, Timpson, Nicholas J., Hughes, Alun D., Deanfield, John E.   +15 more
openaire   +5 more sources

Prospective association between a Mediterranean-style dietary score in childhood and cardiometabolic risk in young adults from the ALSPAC birth cohort

European Journal of Nutrition, 2021
To investigate the prospective association between a children’s relative Mediterranean-style diet score (C-rMED) in childhood and a Cardiometabolic Risk (CMR) score in adolescence/young adulthood in the Avon Longitudinal Study of Parents and Children ...
G. Buckland, C. Taylor, P. Emmett, L. Johnson, K. Northstone   +4 more
semanticscholar   +1 more source

Sex-specific longitudinal association of DNA methylation with lung function

ERJ Open Research, 2021
Investigating whether DNA methylation (DNA-M) at an earlier age is associated with lung function at a later age and whether this relationship differs by sex could enable prediction of future lung function deficit.
Shadia Khan Sunny, Hongmei Zhang, Caroline L. Relton, Susan Ring, Latha Kadalayil, Fawaz Mzayek, Susan Ewart, John W. Holloway, S. Hasan Arshad   +8 more
doaj   +1 more source

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]

, 2015
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M, Casas, J-P, Chaturvedi, N, Fatemifar, G, Hingorani, AD, Hughes, AD, Jarvelin, M-R, Kahonen, M, Kangas, AJ, Kettunen, J, Kivimaki, M, Lawlor, DA, Lehtimaki, T, Mantyselka, P, Perola, M, Raitakari, OT, Salomaa, V, Sattar, N, Smith, GD, Soininen, P, Tiainen, M, Tillin, T, Tynkkynen, T, Vanhala, M, Wang, Q, Wurtz, P   +25 more
core   +2 more sources

SERPINA1 gene polymorphisms in a population‐based ALSPAC cohort

Pediatric Pulmonology, 2019
Abstract Background There is an association between persistent preschool wheezing phenotypes and school‐age asthma. These wheezing/asthma phenotypes likely represent clinical entities having specific genetic risk factors.
David S. DeLuca, Edita Poluzioroviene, Vaida Taminskiene, Sabine Wrenger, Algirdas Utkus, Algirdas Valiulis, Tomas Alasevičius, John Henderson, Andrew Bush, Tobias Welte, Sabina Janciauskiene, Arunas Valiulis   +11 more
openaire   +3 more sources

Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts

Annals of Human Biology, 2020
Background It is unclear if puberty timing influences future physical activity (PA). Aim To investigate the association of puberty timing with PA across adolescence and adulthood. Subjects and methods Data were from two British cohorts. Participants from
Ahmed Ehakeem, Celia L. Gregson, Jon H. Tobias, Deborah A. Lawlor   +3 more
doaj   +1 more source

Trimester effects of source-specific PM10 on birth weight outcomes in the Avon Longitudinal Study of Parents and Children (ALSPAC)

Environmental Health, 2021
Background Evidence suggests that exposure to particulate matter with aerodynamic diameter less than 10 μm (PM 10 ) is associated with reduced birth weight, but information is limited on the sources of PM 10 and exposure misclassification from assigning ...
Yingxin Chen, S. Hodgson, J. Gulliver, R. Granell, A. J. Henderson, Y. Cai, A. Hansell   +6 more
semanticscholar   +1 more source