Results 91 to 100 of about 28,483 (297)

Contact Aspiration Alone or Combined With Stent Retriever Thrombectomy for Middle Cerebral Artery Large Vessel Occlusion

Journal of Neuroimaging, Volume 35, Issue 4, July/August 2025.
ABSTRACT Background and Purpose The effectiveness of a large‐bore aspiration catheter for contact aspiration (CA) thrombectomy is compared to the combined use of an aspiration catheter and a stent retriever (CA+SR) for large vessel occlusion (LVO). We assessed the efficacy and safety of CA alone versus CA+SR as first‐line treatment for middle cerebral ...
Pedro Navia, Andres Fernandez‐Prieto, Alberto Alvarez‐Muelas, Ángel Calleja, Joaquin Ortega, Carlos Domínguez, Antonio Sagredo, Amado Rodríguez‐Benítez, Juan García‐Villanego, Alberto Martínez‐Calvo, Daniel Cubillo‐Prieto, Carmen de la Rosa, Antonio Mosqueira, Rebeca Bermejo‐Garcés, Juan Chaviano, Isabel Bermúdez‐Coronel, Carlos Pérez‐García, Carlos Manuel Rodriguez‐Paz, Carlos Hidalgo‐Barranco, Javier Maynar, Jose Luis Caniego, Juan David Molina‐Nuevo, Víctor Maestro, Juan Manuel Sanchís‐García, Oscar Balboa, Mario Martínez‐Galdamez, Eñaut Garmendia, Marc Comas‐Cufí, Josep Puig, Joaquín Zamarro   +29 more
wiley   +1 more source

Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 6, June 2025.
ABSTRACT Introduction Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality globally. Standard antiplatelet therapies, while partially effective, do not fully inhibit all pathways of platelet aggregation, leaving patients at risk of recurrent thrombotic events. Tirofiban, a glycoprotein IIb/IIIa receptor inhibitor, has shown promise
Abdullah Bin Kamran, Ahmed Bazil Bin Khalil, Ayesha Muhammad, Hira Arshad, Fatima Nazir, Muhammad Mateen Ali, M. Mairaj Umar, Muhammad Farhan, Sudhair Alam, Javed Iqbal   +9 more
wiley   +1 more source

Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography. [PDF]

, 2017
BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid ...
Liang, John W., Stein, Laura, Weinberger, Jesse   +2 more
core   +2 more sources

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

Med Research, Volume 1, Issue 1, Page 62-102, June 2025.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li, Yuxuan Wan, Alan Jiao, Ke Jiang, Gaoyuan Cui, Jinxin Tang, Simin Yu, Zhengang Hu, Songfeng Zhao, Zhenjie Yi, Lifu Long, Yang Yang, Xuehao Cui, Chunrun Qu   +13 more
wiley   +1 more source

A Systematic Review of the Efficacy and Safety of Tenecteplase Versus Alteplase in Acute Ischemic Stroke: A Time to Pass the Torch

Stroke: Vascular and Interventional Neurology
Alteplase, a biosynthetic form of human tissue‐type plasminogen activator, is Food and Drug Administration‐approved for the treatment of acute ischemic stroke and currently the standard of care for thrombolytic therapy.
Miguel Rodriguez, Christian Sidebottom, Drew A. Wells, Thirumalaivasan Dhasakeerthi, Lisa Hayes, Cheran Elangovan, Balaji Krishnaiah   +6 more
doaj   +1 more source

Outcome of Treatment with Intravenous Alteplase in Acute Stroke Patients [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2023
Background and Objective: Stroke is one of the main causes of death and disability in the world, and its treatment includes the re-supply of blood to the brain tissue using different methods, including alteplase injection.
H Nemati, P Saadat, A Ahmadi Ahangar, V Nematian, S Alijanpour, A Bijani   +5 more
doaj  

Efficacy, Influencing Factors, and Safety of Alteplase Intravenous Thrombolysis in Patients with Acute Ischemic Stroke Combined with Atrial Fibrillation

Journal of Chemistry, 2022
Ischemic stroke is the most common type of stroke. Intravenous thrombolytic therapy with alteplase is currently the most effective method to improve the prognosis of patients with acute cerebral infarction.
Yongyin Zhang, Haoye Cai, Hao Shu, Ruqian He, Xuerong Huang, Xiaoyi Song   +5 more
doaj   +1 more source

Prospective Observational Cohort Study of Tenecteplase Versus Alteplase in Routine Clinical Practice

medRxiv, 2022
Background: A 10-hospital regional network transitioned to tenecteplase as the standard of care stroke thrombolytic in September 2019 because of potential workflow advantages and reported noninferior clinical outcomes relative to alteplase in meta ...
S. Warach, A. Dula, T. Milling, Samantha Miller, Leigh Allen, Nathan D Zuck, Collin Miller, C. Jesser, Lotika R Misra, Jefferson T. Miley, M. Mawla, Ming-Chieh Ding, J. Bertelson, A. Tsui, J. Jefferson, Holly M Davison, Darshan N. Shah, Kent T Ellington, M. Padrick, Alan S Nova, Vivek R. Krishna, L. Davis, D. Paydarfar   +22 more
semanticscholar   +1 more source

The association of neutrophil-lymphocyte ratio and lymphocyte-monocyte ratio with 3-month clinical outcome after mechanical thrombectomy following stroke [PDF]

, 2020
Background and aim Neutrophil-lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR) are associated with clinical outcomes in malignancy, cardiovascular disease and stroke.
Alakbarzade, V, Bridge, L, Clark, CN, Clarke, B, Khan, U, Lux, D, Pereira, AC, Zhang, L   +7 more
core   +1 more source

Cost-effective analysis of mechanical thrombectomy alone in the treatment of acute ischaemic stroke: a Markov modelling study

BMJ Open, 2022
Objective Recently, a randomised controlled trial (DIRECT-MT) demonstrated that mechanical thrombectomy (MT) was non-inferior to MT with intravenous alteplase as to the functional outcomes.
Aihua Liu, Xin Tong, Jigang Chen, Mingyang Han, Linjin Ji, Songfeng Zhao, Yongkai Qin, Lang Liu   +7 more
doaj   +1 more source