Results 11 to 20 of about 20,254 (207)

Use of carefully titrated ultra‐low doses of alteplase in infected haemothorax caused by initial alteplase use to drain loculated malignant pleural effusion

Respirology Case Reports, 2023
Alteplase as a fibrinolytic can be used to break up fibrin to encourage clot breakdown for clinical use. In the pleural space, it is used for symptomatic loculated malignant pleural effusions and pleural infections and can potentially avoid the need for ...
Jeong Suk Oh, Chris Yoo, Donny Wong
doaj   +1 more source

Economic evaluation of endovascular treatment for acute ischaemic stroke in Thailand

BMJ Open, 2022
Objectives Endovascular therapy (EVT) has proven to be clinically effective in treating large vessel occlusion acute ischaemic stroke (AIS), either alone or in combination with intravenous alteplase.
Yot Teerawattananon, Wanrudee Isaranuwatchai, Waranya Rattanavipapong, Yongchai Nilanont, Thanaboon Worakijthamrongchai, Budsadee Soboon, Vilawan Luankongsomchit, Mananchaya Kongmuangpuk   +7 more
doaj   +1 more source

Effect of Alteplase Use on Outcomes in Patients With Atrial Fibrillation: Analysis of the Initiation of Anticoagulation After Cardioembolic Stroke Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Intravenous alteplase improves outcome after acute ischemic stroke without a benefit in 90‐day mortality. There are limited data on whether alteplase is associated with reduced mortality in patients with atrial fibrillation (AF)‐related ...
Shadi Yaghi, Eva Mistry, Adam de Havenon, Christopher R. Leon Guerrero, Amre Nouh, Ava L. Liberman, James Giles, Angela Liu, Muhammad Nagy, Ashutosh Kaushal, Idrees Azher, Brian Mac Grory, Hiba Fakhri, Kiersten Brown Espaillat, Syed Daniyal Asad, Hemanth Pasupuleti, Heather Martin, Jose Tan, Manivannan Veerasamy, Charles Esenwa, Natalie Cheng, Khadean Moncrieffe, Iman Moeini‐Naghani, Mithilesh Siddu, Erica Scher, Tushar Trivedi, Teddy Wu, Muhib Khan, Salah Keyrouz, Karen Furie, Nils Henninger   +30 more
doaj   +1 more source

Tenecteplase vs. alteplase for acute ischemic stroke: a systematic review

International Journal of Emergency Medicine, 2022
Introduction Thrombolysis for acute ischemic stroke (AIS) with alteplase is the currently approved therapy for patients who present within 4.5 h of symptom onset and meet criteria.
Neha Potla, Latha Ganti
doaj   +1 more source

Clinical efficacy and safety analysis of argatroban and alteplase treatment regimens for acute cerebral infarction

Journal of Neurorestoratology, 2022
ObjectiveThis study compared the clinical efficacy and safety of argatroban and alteplase in the treatment of acute cerebral infarction.MethodsThis study retrospectively analyzed 131 patients admitted for acute cerebral infarction within 48 h of onset ...
Lifang Xu, Xiaofeng Yang, He Gao, Xin Wang, Bo Zhou, Yan Li, Lin Li, Xiaoling Guo, Liqun Ren   +8 more
doaj   +1 more source

Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA) [PDF]

, 2010
<p><b>Background and Purpose:</b> Thrombolysis for acute ischemic stroke in patients aged >80 years is not approved in some countries due to limited trial data in the very elderly.
Bluhmki, E., Diener, H.-C., Lees, K.R., Lyden, P.D., Mishra, N.K.   +4 more
core   +1 more source

Tenecteplase or Alteplase Better in Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion: A Single Center Observational Study

Medicina, 2022
Background and Objectives: The study aimed to investigate the efficacy of intravenous thrombolysis with Tenecteplase before thrombectomy for acute ischemic stroke (AIS) patients compared with previous results using Alteplase.
Agnete Teivane, Kristaps Jurjāns, Jānis Vētra, Jekaterina Grigorjeva, Karlis Kupcs, Rytis Masiliūnas, Evija Miglāne   +6 more
doaj   +1 more source

Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: individual-patient-data meta-analysis of randomized trials [PDF]

, 2017
Background: The recommended maximum age and time window for intravenous alteplase treatment of acute ischemic stroke differs between the Europe Union and United States.
Colin Baigent, Danilo Toni, Erich Bluhmki, Geoffrey A Donnan, Geoffrey Cohen, George Howard, Gregory Albers, Gregory del Zoppo, James C Grotta, Jean-Marc Olivot, Joanna M Wardlaw, Jonathan Emberson, Kazunori Toyoda, Kennedy R Lees, Lisa Blackwell, Maarten G Lansberg, Mark Parsons, Markku Kaste, Masatoshi Koga, Nils Wahlgren, null null, Patrick Lyden, Peter AG Sandercock, Richard I Lindley, Rüdiger von Kummer, Stephen M Davis, Thomas Brott, Werner Hacke, William N Whiteley   +28 more
core   +5 more sources

Transcranial Histotripsy Clot and Tissue Ablation for Intracerebral Hemorrhage Evacuation and Other Brain Applications

, 2023
STROKE: Vascular and Interventional Neurology, EarlyView.
Jonathan Sukovich, Zhen Xu, Aditya S. Pandey   +2 more
wiley   +1 more source

Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) [PDF]

, 2008
<p><b>Background and Purpose:</b> The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with ...
Ahmed, Niaz, Aichner, Franz, Bluhmki, Erich, Davalos, Antoni, Eriksson, Niclas, Erilä, Terttu, Ford, Gary A, Grond, Martin, Hacke, Werner, Hennerici, Michael G, Kaste, Markku, Köhrmann, Martin, Larrue, Vincent, Lees, Kennedy R, Machnig, Thomas, Peeters, André, Roine, Risto O, Toni, Danilo, Vanhooren, Geert, Wahlgren, Nils   +19 more
core   +2 more sources