Results 21 to 30 of about 28,483 (297)

Aspiration Thrombectomy After Intravenous Alteplase Versus Intravenous Alteplase Alone [PDF]

Stroke, 2016
Background and Purpose— Thrombectomy, primarily with stent retrievers with or without adjunctive aspiration, provided clinical benefit across multiple prospective randomized trials. Whether this benefit is exclusive to stent retrievers is unclear.
Zaidat, Osama O., von Kummer, Rüdiger, Yoo, Albert J., Gupta, Rishi, Lopes, Demetrius, Frei, Don, Shownkeen, Harish, Budzik, Ron, Ajani, Zahra A., Grossman, Aaron, Altschul, Dorethea, McDougall, Cameron, Blake, Lindsey, Fitzsimmons, Brian-Fred, Yavagal, Dileep, Terry, John, Farkas, Jeffrey, Lee, Seon Kyu, Baxter, Blaise, Wiesmann, Martin, Knauth, Michael, Heck, Donald, Hussain, Syed, Chiu, David, Alexander, Michael J., Malisch, Timothy, Kirmani, Jawad, Miskolczi, Laszlo, Khatri, Pooja, Mocco, J.   +29 more
openaire   +4 more sources

Effect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2023
Importance Previous studies suggested a benefit of argatroban plus alteplase (recombinant tissue-type plasminogen activator) in patients with acute ischemic stroke (AIS). However, robust evidence in trials with large sample sizes is lacking.
Hui-Sheng Chen, Yu Cui, Zhong-he Zhou, Ying-Jie Dai, Gao-Hua Li, Zhao-Long Peng, Yi Zhang, Xiao-Dong Liu, Zhi-Mei Yuan, Chang-Hao Jiang, Qing-Cheng Yang, Ying-Jie Duan, Guang-Bin Ma, Li-Wei Zhao, Rui-Xian Wang, Yuan-Lin Sun, Lei Shen, E. Wang, Li‐Hua Wang, Ye-Fang Feng, Feng-Yun Wang, Ren-Lin Zou, He-Ping Yang, Kai Wang, Duo-Lao Wang, Yi-Long Wang   +25 more
semanticscholar   +1 more source

A Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke.

New England Journal of Medicine, 2021
BACKGROUND The value of administering intravenous alteplase before endovascular treatment (EVT) for acute ischemic stroke has not been studied extensively, particularly in non-Asian populations.
N. LeCouffe, M. Kappelhof, K. Treurniet, L. Rinkel, A. Bruggeman, O. Berkhemer, L. Wolff, H. van Voorst, M. Tolhuisen, D. Dippel, A. van der Lugt, A. V. van Es, J. Boiten, G. J. Lycklama à Nijeholt, K. Keizer, R. Gons, Lonneke S. F. Yo, R. V. van Oostenbrugge, W. V. van Zwam, B. Roozenbeek, H. B. van der Worp, Rob H. Lo, I. R. van den Wijngaard, I. D. de Ridder, V. Costalat, C. Arquizan, R. Lemmens, J. Demeestere, J. Hofmeijer, Jasper M. Martens, W. Schonewille, J. Vos, M. Uyttenboogaart, R. Bokkers, J. V. van Tuijl, Hans G. Kortman, F. Schreuder, H. Boogaarts, K. D. de Laat, L. V. van Dijk, H. D. den Hertog, B. V. van Hasselt, P. Brouwers, Tomas Bulut, M. Remmers, A. V. van Norden, Farshad Imani, A. Rozeman, O. Elgersma, P. Desfontaines, D. Brisbois, Y. Samson, F. Clarençon, G. M. Krietemeijer, A. Postma, P. van Doormaal, R. van den Berg, A. van der Hoorn, L. Beenen, D. Nieboer, H. Lingsma, B. Emmer, J. Coutinho, C. Majoie, Y. Roos   +64 more
semanticscholar   +1 more source

Low-Dose vs. Standard-Dose Intravenous Alteplase in Bridging Therapy Among Patients With Acute Ischemic Stroke: Experience From a Stroke Center in Vietnam

Frontiers in Neurology, 2021
Background: To date, the role of bridging intravenous thrombolysis before mechanical thrombectomy (MTE) is controversial but still recommended in eligible patients.
Duy Ton Mai, Duy Ton Mai, Viet Phuong Dao, Van Chi Nguyen, Van Chi Nguyen, Dang Luu Vu, Dang Luu Vu, Tien Dung Nguyen, Xuan Trung Vuong, Quoc Viet Bui, Ha Quan Phan, Quang Tho Pham, Hoang Kien Le, Anh Tuan Tran, Quang Anh Nguyen, Phuc Duc Dang, Hoang Nguyen, Hoang Thi Phan, Hoang Thi Phan   +18 more
doaj   +1 more source

Intravenous thrombolysis for acute ischemic stroke: From alteplase to tenecteplase

Brain Circulation, 2023
Stroke is one of the primary causes of morbidity and death worldwide. While intravenous (IV) thrombolysis with alteplase has been widely proven to be beneficial for acute ischemic stroke patients, it still has many limitations.
Nan Yang, Han Lee, Chuanjie Wu
semanticscholar   +1 more source

Use of carefully titrated ultra‐low doses of alteplase in infected haemothorax caused by initial alteplase use to drain loculated malignant pleural effusion

Respirology Case Reports, 2023
Alteplase as a fibrinolytic can be used to break up fibrin to encourage clot breakdown for clinical use. In the pleural space, it is used for symptomatic loculated malignant pleural effusions and pleural infections and can potentially avoid the need for ...
Jeong Suk Oh, Chris Yoo, Donny Wong
doaj   +1 more source

Economic evaluation of endovascular treatment for acute ischaemic stroke in Thailand

BMJ Open, 2022
Objectives Endovascular therapy (EVT) has proven to be clinically effective in treating large vessel occlusion acute ischaemic stroke (AIS), either alone or in combination with intravenous alteplase.
Yot Teerawattananon, Wanrudee Isaranuwatchai, Waranya Rattanavipapong, Yongchai Nilanont, Thanaboon Worakijthamrongchai, Budsadee Soboon, Vilawan Luankongsomchit, Mananchaya Kongmuangpuk   +7 more
doaj   +1 more source

Effect of Alteplase Use on Outcomes in Patients With Atrial Fibrillation: Analysis of the Initiation of Anticoagulation After Cardioembolic Stroke Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Intravenous alteplase improves outcome after acute ischemic stroke without a benefit in 90‐day mortality. There are limited data on whether alteplase is associated with reduced mortality in patients with atrial fibrillation (AF)‐related ...
Shadi Yaghi, Eva Mistry, Adam de Havenon, Christopher R. Leon Guerrero, Amre Nouh, Ava L. Liberman, James Giles, Angela Liu, Muhammad Nagy, Ashutosh Kaushal, Idrees Azher, Brian Mac Grory, Hiba Fakhri, Kiersten Brown Espaillat, Syed Daniyal Asad, Hemanth Pasupuleti, Heather Martin, Jose Tan, Manivannan Veerasamy, Charles Esenwa, Natalie Cheng, Khadean Moncrieffe, Iman Moeini‐Naghani, Mithilesh Siddu, Erica Scher, Tushar Trivedi, Teddy Wu, Muhib Khan, Salah Keyrouz, Karen Furie, Nils Henninger   +30 more
doaj   +1 more source

Tenecteplase vs. alteplase for treatment of acute ischemic stroke: A systematic review and meta-analysis of randomized trials

Frontiers in Neurology, 2023
Background and objectives Several randomized controlled trials (RCTs) have compared tenecteplase to alteplase for treatment of acute ischemic stroke (AIS). Yet, there is no meta-analysis that includes the latest published RCTs of 2022.
Hassan Kobeissi, S. Ghozy, Bilal Turfe, C. Bilgin, R. Kadirvel, D. Kallmes, W. Brinjikji, A. Rabinstein   +7 more
semanticscholar   +1 more source

Transcranial Histotripsy Clot and Tissue Ablation for Intracerebral Hemorrhage Evacuation and Other Brain Applications

, 2023
STROKE: Vascular and Interventional Neurology, EarlyView.
Jonathan Sukovich, Zhen Xu, Aditya S. Pandey   +2 more
wiley   +1 more source