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Beyond the exam : An alternative online assessment toolkit
, 2022 This project is made possible with funding by the Government of Ontario and through eCampusOntario’s support of the Virtual Learning Strategy.I. Designing and Teaching with Digital Fluency - Building AssessmentsII.
Duncan, Samantha +8 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Practical steps to integrate life cycle thinking into alternative assessment
Sustainability Science and TechnologyCurrent alternative assessment (AA) methods for chemicals have yet to be completed from the entire life cycle perspective. Conventionally, AA efforts compare chemical alternatives by examining toxicity, hazard, exposure, and physicochemical properties to
John D Chea, Michael A Gonzalez
doaj +1 more source
Arctic Ocean Acidification 2013: An Overview
, 2014 Report presenting a summary of the first comprehensive assessment of Arctic Ocean acidification (AOA) conducted by the Arctic Monitoring and Assessment Programme (AMAP).
Arctic Monitoring and Assessment Programme
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Problem-Solving Framework in Algebra Through Backward Error-Analysis
HexagonThis study aimed to propose Backward Error-Analysis (BEA) as an alternative assessment method in algebra by evaluating its relevance and effectiveness and developing a problem-solving framework for classroom use.
Alexander Casajes +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Alternative assessment for visually impaired student
, 2011 Essay writing in a scientific style is considered to be a key skill for students studying Biological Sciences and Sport and Exercise science. An assessment in the core first year module “Introductory Physiology” therefore includes an essay on one of 4 ...
Mariusz Orwat +3 more
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source