Results 181 to 190 of about 2,258,983 (316)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Validación de métodos alternativos para análisis microbiológico de alimentos y aguas. cualitativos

open access: yesRevista Cubana de Higiene y Epidemiología
Internacionalmente han aumentado las exigencias para la adopción de nuevos métodos microbiológicos para el análisis de aguas y alimentos. Estos son adoptados cuando ofrecen rapidez, menor laboriosidad, son más sencillos, entre otras ventajas. Para lograr
Meylín Ortega González   +2 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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