Results 141 to 150 of about 28,556 (226)

Spatial Transcriptomic Characteristics of the Aging Human Ovary

Aging Cell, Volume 25, Issue 1, January 2026.
Troughing constructing a comprehensive spatiotemporal aging atlas on young and aged human ovaries, we revealed distinct cell types, cellular interactions, and aging‐associated gene expression changes due to aging. Specially, we detected an increase in DLK1:NOTCH3 expression which may contribute to the dysregulation of ovarian functions.
Meiling Zhang, Fanghao Guo, Qing Zhang, Qianhui Hu, Di Sun, Yongjian Ma, Yanquan Li, Mengxi Guo, Haixia Ding, Ying Guo, Baicai Yang, Songmao Li, Ningxia Sun, Yuxuan Zheng, Wen Li   +14 more
wiley   +1 more source

Alternative polyadenylation coordinates embryonic development, sexual dimorphism and longitudinal growth in Xenopus tropicalis

, 2019
Xiang Zhou, Yangzi Zhang, Jennifer J. Michal, Lujiang Qu, Shuwen Zhang, Mark R. Wildung, Weiwei Du, Derek Pouchnik, Hui Zhao, Yin Xia, Honghua Shi, Guoli Ji, Jon F. Davis, Gary D. Smith, Michael D. Griswold, Richard M. Harland, Zhihua Jiang   +16 more
openalex   +2 more sources

TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models

The FEBS Journal, Volume 293, Issue 2, Page 348-384, January 2026.
The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir, Joerg Buddenkotte, Majid Ali Alam, Ahmed Own, Randall J. Eck, Brian C. Kraemer, Eckhard Mandelkow, Martin Steinhoff   +7 more
wiley   +1 more source

A Polymorphic 3’UTR Element in ATP1B1 Regulates Alternative Polyadenylation and Is Associated with Blood Pressure

, 2013
Megana Prasad, Kavita Bhalla, Zhen Pan, Jeffrey R. O’Connell, Alan B. Weder, Aravinda Chakravarti, Bin Tian, Yen-Pei C. Chang   +7 more
openalex   +2 more sources

Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development [PDF]

, 2015
Fei Chen, Yu Zhou, Yingchuan Qi, Vishal Khivansara, Hairi Li, Sang Y. Chun, John K. Kim, Xiang‐Dong Fu, Yishi Jin   +8 more
openalex   +1 more source

The Dual Role of the 16mer Motif Within the 3′ Untranslated Region of the Variant Surface Glycoprotein of Trypanosoma brucei

Molecular Microbiology, Volume 125, Issue 1, Page 67-79, January 2026.
A fully conserved 16mer motif is required in the silent VSG to trigger efficient silencing of the expression site (ES)‐resident VSG and a successful exchange of the VSG coat. ABSTRACT The variant surface glycoprotein (VSG) of African trypanosomes is essential for the survival of bloodstream form parasites.
Majeed Bakari‐Soale, Christopher Batram, Henriette Zimmermann, Nicola G. Jones, Markus Engstler   +4 more
wiley   +1 more source

Pepino Mosaic Virus: A Globally Important Tomato Pathogen and a Rising Model in Molecular Virology

Molecular Plant Pathology, Volume 27, Issue 1, January 2026.
Pepino mosaic virus (PepMV) is a globally important tomato pathogen causing fruit quality losses. It comprises multiple genetic types and spreads via seed and mechanical contact. Lacking resistant cultivars, management relies on cross‐protection. PepMV–tomato interactions provide a valuable model for studying virus–plant molecular mechanisms and ...
Jesús R. Úbeda, Livia Donaire, Cristina Alcaide, Miguel A. Aranda   +3 more
wiley   +1 more source

Signatures of mRNA Alternative Polyadenylation in Arabidopsis Leaf Development [PDF]

, 2022
Zhibo Yu, Liwei Hong, Qingshun Quinn Li
openalex   +1 more source

Translational control in plants: from basic mechanisms to environmental and developmental responses

The Plant Journal, Volume 125, Issue 1, January 2026.
SUMMARY Protein synthesis is an essential process for all living organisms and is tightly regulated to ensure the proper production of proteins needed for growth, development, and stress responses. As sessile organisms, plants have evolved distinct mechanisms to regulate translation, allowing them to adapt to their environment.
Jade Lyons, Catharina Merchante, Anna N. Stepanova, Jose M. Alonso   +3 more
wiley   +1 more source

Correction for Ji et al., Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

, 2009

openalex   +1 more source