Results 121 to 130 of about 725 (142)

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, Volume 179, Issue 1, Page 54-71, September 2026.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

Journal of Integrative Plant Biology, Volume 68, Issue 9, Page 3196-3207, September 2026.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang, Jingying Li, Yucai Li, Lei Yan, Christina Seok Yien Yong, Shaoya Li, Yubing He, Lanqin Xia   +7 more
wiley   +1 more source

Independent colonizations of serpentine habitats shape heterogeneous genomic landscapes of lineage diversification

Journal of Systematics and Evolution, Volume 64, Issue 5, Page 1008-1024, September 2026.
Comparing genomic and phenotypic patterns in three diploid plant species co‐occurring in serpentine and adjacent non‐serpentine habitats in the southern Iberian Peninsula reveals repeated, parallel colonization of serpentine habitats, with species‐specific isolation‐by‐distance, population ancestry, and phenotypic differentiation, highlighting ...
Pablo Arrufat, Noelia Hidalgo‐Triana, Nazaret Keen, Jaime Francisco Pereña‐Ortiz, Andrés V. Pérez‐Latorre, Amaia Leunda‐Esnaola, Alexandra García‐Flórez, Vladimir R. Kaberdin, Filip Kolář, David López‐Idiáquez, Peter B. Pearman   +10 more
wiley   +1 more source

APC mutations dysregulate alternative polyadenylation in cancer

Genome Biology
Background Alternative polyadenylation (APA) affects most human genes and is recurrently dysregulated in all studied cancers. However, the mechanistic origins of this dysregulation are incompletely understood.
Austin M. Gabel, Andrea E. Belleville, James D. Thomas, Jose Mario Bello Pineda, Robert K. Bradley   +4 more
doaj   +1 more source

Nonlinearities and Switch‐Like Behavior in Gene Expression: From Genetics to Biochemistry and Back

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Modest changes in transcription‐factor or chromatin‐regulator dosage can have disproportionate effects when gene‐regulatory systems operate near nonlinear thresholds. Sigmoidal input–output relationships, chromatin and cofactor recruitment, and changes in threshold position or response steepness provide molecular routes by which quantitative dosage ...
Reiner A. Veitia, James A. Birchler
wiley   +1 more source

Corrigendum to “NUDT21‐mediated Alternative Polyadenylation of CDK19 Reprograms Cholesterol Biosynthesis to Drive Colorectal Cancer Progression”

Advanced Science, Volume 13, Issue 51, 14 September 2026.
wiley   +1 more source

Cloning of Canine Dsg1 and Evidence for Alternative Polyadenylation [PDF]

Journal of Investigative Dermatology, 2000
Müller, Eliane, Caldelari, Reto, Baron, Agnès, Rohrbach, Beatrice, Wyder, Marianne, Balmer, Vreni, Suter, Maja M., Levine, Roy, Kaplan, Steven   +8 more
openaire   +2 more sources

Alternative Polyadenylation in CD2 Expression

, 2013
openaire   +2 more sources

Advances in Alternative Polyadenylation in Tumors

Advances in Clinical Medicine
openaire   +1 more source

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Alternative polyadenylation regulation: insights from sequential polyadenylation

Transcription, 2022
The processing of the proximal and distal poly(A) sites in alternative polyadenylation (APA) has long been thought to independently occur on pre-mRNAs during transcription. However, a recent study by our groups demonstrated that the proximal sites for many genes could be activated sequentially following the distal ones, suggesting a multi-cleavage-same-
Peng Tang, Yu Zhou
openaire   +2 more sources