Results 151 to 160 of about 51,497 (273)

RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts

open access: yesCell Reports, 2021
Summary: RBFOX2, which has a well-established role in alternative splicing, is linked to heart diseases. However, it is unclear whether RBFOX2 has other roles in RNA processing that can influence gene expression in muscle cells, contributing to heart ...
Jun Cao   +17 more
doaj  

Comparison of transcriptional activity profiling by metabolic labeling or nuclear RNA sequencing

open access: yesThe Plant Journal, Volume 123, Issue 3, August 2025.
Significance Statement A uracil analog, EU, can be incorporated in vivo into newly synthesized RNA during normal transcription. In maize root tips, we found the entire population of nuclear RNA is remarkably similar in composition to newly synthesized RNA, but both differ substantially from cellular RNA, which is largely of cytoplasmic origin.
E. E. Wear   +5 more
wiley   +1 more source

InPAS: An R/Bioconductor Package for Identifying Novel Polyadenylation Sites and Alternative Polyadenylation from Bulk RNA-seq Data

open access: yesFrontiers in Bioscience-Scholar
Background: Alternative cleavage and polyadenylation (APA) is a crucial post-transcriptional gene regulation mechanism that regulates gene expression in eukaryotes by increasing the diversity and complexity of both the transcriptome ...
Jianhong Ou   +4 more
doaj   +1 more source

Differential regulation of expression of the multiple ADP/ATP translocase genes in human cells [PDF]

open access: yes, 1991
The expression of the genes encoding the three isoforms of the human ADP/ATP translocase (T1, T2, and T3) has been investigated in cultured cell systems under different experimental conditions, using isoform- specific probes.
Attardi, Giuseppe, Lunardi, Joël
core  

Genome level analysis of rice mRNA 3′-end processing signals and alternative polyadenylation [PDF]

open access: gold, 2008
Yingjia Shen   +6 more
openalex   +1 more source

High-Resolution RNA Maps Suggest Common Principles of Splicing and Polyadenylation Regulation by TDP-43

open access: yesCell Reports, 2017
Summary: Many RNA-binding proteins (RBPs) regulate both alternative exons and poly(A) site selection. To understand their regulatory principles, we developed expressRNA, a web platform encompassing computational tools for integration of iCLIP and RNA ...
Gregor Rot   +9 more
doaj  

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