Results 171 to 180 of about 3,647,679 (259)

Differential regulation of expression of the multiple ADP/ATP translocase genes in human cells [PDF]

, 1991
The expression of the genes encoding the three isoforms of the human ADP/ATP translocase (T1, T2, and T3) has been investigated in cultured cell systems under different experimental conditions, using isoform- specific probes.
Attardi, Giuseppe, Lunardi, Joël
core  

Altered polyadenylation site usage in SERPINA1 3’UTR in response to cellular stress affects A1AT protein expression

Scientific Reports
Alternative polyadenylation results in different 3’ isoforms of messenger RNA (mRNA) transcripts. Alternative polyadenylation in the 3’ untranslated region (3’UTR) can alter RNA localization, stability and translational efficiency.
F. N. U. Jiamutai, Abigail Hatfield, Austin Herbert, Debarati Majumdar, Vijay Shankar, Lela Lackey   +5 more
doaj   +1 more source

The genetics and genomics of Trypanosoma cruzi [PDF]

, 2007
Trypanosoma cruzi is a kinetoplastid parasite that causes Chagas disease. Trypanosomes are unusual organisms in many aspects of its genetics and molecular and cellular biology and considered a paradigm of the exception of the rule in the eukaryotic ...
Vazquez, Martin Pablo
core  

InPAS: An R/Bioconductor Package for Identifying Novel Polyadenylation Sites and Alternative Polyadenylation from Bulk RNA-seq Data

Frontiers in Bioscience-Scholar
Background: Alternative cleavage and polyadenylation (APA) is a crucial post-transcriptional gene regulation mechanism that regulates gene expression in eukaryotes by increasing the diversity and complexity of both the transcriptome ...
Jianhong Ou, Haibo Liu, Sungmi Park, Michael R. Green, Lihua Julie Zhu   +4 more
doaj   +1 more source

Deletion of Gpr27 in vivo reduces insulin mRNA but does not result in diabetes. [PDF]

, 2020
Gpr27 is a highly conserved, orphan G protein coupled receptor (GPCR) previously implicated in pancreatic beta cell insulin transcription and glucose-stimulated insulin secretion in vitro. Here, we characterize a whole-body mouse knockout of Gpr27. Gpr27
Chopra, Deeksha G, Hennings, Thomas G, Ku, Gregory M, Yiv, Nicholas, Zhang, Yaohuan   +4 more
core  

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation

Molecular Systems Biology, 2016
Alternative polyadenylation (APA), which is regulated by both cis‐elements and trans‐factors, plays an important role in post‐transcriptional regulation of eukaryotic gene expression.
Mei‐Sheng Xiao, Bin Zhang, Yi‐Sheng Li, Qingsong Gao, Wei Sun, Wei Chen   +5 more
doaj   +1 more source

NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis. [PDF]

, 2019
The 5' end of a eukaryotic mRNA transcript generally has a 7-methylguanosine (m7G) cap that protects mRNA from degradation and mediates almost all other aspects of gene expression.
Cai, Zongwei, Chen, Xuemei, Ni, Min, Shao, Xiaojian, Xia, Yiji, Zhang, Hailei, Zhang, Shoudong, Zhong, Huan   +7 more
core  

Deciphering Estrus Expression in Gilts: The Role of Alternative Polyadenylation and LincRNAs in Reproductive Transcriptomics

Animals
The fertility rate and litter size of female pigs are critically affected by the expression of estrus. The objective of this study was to elucidate the regulatory mechanisms of estrus expression by analyzing the differential expression of genes and long ...
Mingzheng Liu, Jiahao Chen, Chunlei Zhang, Shuhan Liu, Xiaohuan Chao, Huan Yang, Asim Muhammad, Bo Zhou, Weiping Ao, Allan P. Schinckel   +9 more
doaj   +1 more source

The transcriptional terminator XRN2 and the RNA-binding protein Sam68 link alternative polyadenylation to cell cycle progression in prostate cancer

Nature Structural & Molecular Biology, 2022
M. Pieraccioli, Cinzia Caggiano, Luca Mignini, Chuwei Zhong, G. Babini, R. Lattanzio, S. D. Di Stasi, Bin Tian, C. Sette, P. Bielli   +9 more
semanticscholar   +1 more source

3'UTR Mapping Reveals Alternative Polyadenylation in Right Ventricular Failure. [PDF]

Circ Res
Neupane R, Natarajan K, Suarez EE, Pownall HJ, Huang KL, Wagner EJ, Verma AK, Majji R, Yalamanchili HK, Guha A, Thandavarayan RA.   +10 more
europepmc   +1 more source