Results 191 to 200 of about 30,645 (223)

Poly(A) tail dynamics, non-adenine incorporation and alternative polyadenylation shape the host transcriptome in COVID-19 pathogenesis. [PDF]

open access: yesSci Rep
Maździarz MA   +11 more
europepmc   +1 more source

Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns [PDF]

open access: yesRNA Biology, 2016
Alternative polyadenylation has been implicated as an important regulator of gene expression. In some cases, alternative polyadenylation is known to couple with alternative splicing to influence last intron removal.
Maliheh Movassat   +2 more
exaly   +2 more sources

Alternative polyadenylation regulation: insights from sequential polyadenylation

Transcription, 2022
The processing of the proximal and distal poly(A) sites in alternative polyadenylation (APA) has long been thought to independently occur on pre-mRNAs during transcription. However, a recent study by our groups demonstrated that the proximal sites for many genes could be activated sequentially following the distal ones, suggesting a multi-cleavage-same-
Peng Tang, Yu Zhou
openaire   +2 more sources

Alternative polyadenylation and the stress response

WIREs RNA, 2019
AbstractThe cellular stress response is a universal mechanism necessary for the survival of all organisms. This multifaceted process is primarily driven by regulation of gene expression to produce an intracellular environment suitable for promoting cell survival and recovery.
Jason Sadek   +4 more
openaire   +2 more sources

Evaluation of a novel short polyadenylation signal as an alternative to the SV40 polyadenylation signal

Plasmid, 2006
The soluble neuropilin-1 (sNRP-1) gene employs an extremely short dual function polyadenylation (pA) signal/stop codon that is efficient for termination of gene transcription and translation in vivo. However, the functionality and usefulness of this signal in regard to other genes is unknown.
Trevor J, McFarland   +5 more
openaire   +2 more sources

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