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Vancomycin is one of the “last-line” classes of antibiotics used in the treatment of life-threatening infections caused by Gram-positive bacteria. Even though vancomycin was discovered in the 1950s, it was widely used after the 1980s for the treatment of
Panditharathnalage Nishantha Kumara Wijesekara +3 more
doaj +1 more source
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Advancing EIA framework for deep-sea mining: a critical review of current regulations and proposals
On June 25, 2021, Nauru informed the Council of International Seabed Authority that its sponsored entity Nauru Ocean Resources Inc. intended to apply for approval of a plan of work for exploitation in the international seabed area and requested the ...
Yu Ning, Yu Ning
doaj +1 more source
Distinguishing semantic components of attitude verbs via the German modifier genau
This paper presents novel data from German: certain attitude verbs such as wissen ('know') as well as all verbs of perception are compatible with the modifier genau ('exactly') which is usually associated with expressing precision.
Valerie Wurm
doaj +1 more source
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher +8 more
wiley +1 more source
TRIPOLI-4® Monte Carlo transport code and FIFRELIN fission model have been coupled by means of external files so that neutron transport can take into account fission distributions (multiplicities and spectra) that are not averaged, as is the case when ...
Petit Odile +5 more
doaj +1 more source
Der vorliegende Artikel soll einen Beitrag zu theoretischen Überlegungen einer Technikfolgenabschätzung (TA) der Alternativen leisten. Ausgehend von der Annahme, dass TA seit ihrer Entstehung den Anspruch auf die Entwicklung von (technischen ...
Paulina Dobroć +3 more
doaj +1 more source
Bolivia, una experiencia alternativa
Se analizan los límites y las posibilidades del gobierno de Evo Morales en Bolivia, teniendo en cuenta tanto el contexto socioeconómico como las nuevas experiencias parlamentarias de izquierda en el continente latinoamericano.
Helio Gallardo
doaj
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Adams, Colin +4 more
openaire +2 more sources
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker +7 more
wiley +1 more source

