Drug Company Research and Animal Use [PDF]
, 2021 Over the years, the use of laboratory animals by drug companies and other commercial laboratories has elicited more than its share of criticism. In the late 1970s, animal advocates turned their attention to the testing of cosmetics and personal care ...
Rowan, Andrew N.
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EURL ECVAM Strategy to replace, reduce and refine the use of fish in aquatic toxicity and bioaccumulation testing [PDF]
, 2014 The assessment of aquatic toxicity and bioaccumulation are important components of the environmental hazard and risk assessment of all types of chemicals, and are therefore included in several pieces of European Union and international legislation.
HALDER MARIA ELISABETH +3 more
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Alternatives to animal experimentation [PDF]
BMJ, 2007 After two decades of decline, the use of animals in research is beginning to rise again. Geoff Watts examines replacement techniques and the potential for eliminating the need to use living ...
openaire +3 more sources
Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies [PDF]
, 2015 By reducing energy density, low-energy sweeteners (LES) might be expected to reduce energy intake (EI) and body weight (BW). To assess the totality of the evidence testing the null hypothesis that LES exposure (versus sugars or unsweetened alternatives ...
de Graaf, C +10 more
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Has Toxicity Testing Moved into the 21st Century? A Survey and Analysis of Perceptions in the Field of Toxicology. [PDF]
, 2017 BackgroundTen years ago, leaders in the field of toxicology called for a transformation of the discipline and a shift from primarily relying on traditional animal testing to incorporating advances in biotechnology and predictive methodologies into ...
Allard, Patrick +6 more
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Brain organoids and organoid intelligence from ethical, legal, and social points of view
Frontiers in Artificial IntelligenceHuman brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain.
Thomas Hartung +3 more
doaj +1 more source
A worldwide survey on the use of animal‐derived materials and reagents in scientific experimentation
Engineering in Life Sciences, 2022 The use of cell and tissue‐based methods in basic, applied and regulatory science has been increasing exponentially. Animal‐derived components, including serum, coating materials, growth factors and antibodies are routinely used in cell/tissue cultures ...
Manuela Cassotta +7 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Mosquito-borne flaviviruses can cause disease in the nervous system, resulting in a significant burden of morbidity and mortality. Disease models are necessary to understand neuropathogenesis and identify potential therapeutics and vaccines.
Megan Chesnut +10 more
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Progress Toward Replacing Animals in Toxicity Testing for Cosmetics [PDF]
, 2012 In the 1980’s, animal rights activists successfully motivated the cosmetic industry to begin researching alternatives to animal tests.
Nye, Marisa B.
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EURL ECVAM Recommendation on the Zebrafish Embryo Acute Toxicity Test Method (ZFET) for Acute Aquatic Toxicity Testing [PDF]
, 2014 Acute fish toxicity testing is an important component of the environmental hazard assessment of chemicals. Since many years, (zebra-)fish embryo-based methods have been proposed as alternatives to the acute fish toxicity test carried out with juvenile or
AMCOFF SVEN PATRIK +4 more
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