Results 91 to 100 of about 843,251 (286)

In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions

Frontiers in Immunology
BackgroundHypoxia plays a pivotal role in modulating immune responses, especially in neutrophils, which are essential components of the innate immune system.
Yi Ye, Yi Ye, Yi Ye, Yanjun Wang, Yanjun Wang, Yanjun Wang, Yanjun Wang, Qiying Xu, Qiying Xu, Qiying Xu, Qiying Xu, Juanli Liu, Juanli Liu, Juanli Liu, Juanli Liu, Ziqi Yang, Tana Wuren, Tana Wuren, Tana Wuren, Ri-Li Ge, Ri-Li Ge, Ri-Li Ge   +21 more
doaj   +1 more source

Evaluation of hypoxic injuries in 7 cell lines derived from different human tissues

Di-san junyi daxue xuebao, 2019
Objective To observe hypoxic injuries in 7 cell lines derived from different human tissues to identify a cell model that is sensitive to acute hypoxic injury. Methods Seven cell lines derived from different human tissues, namely CCD 841 CoN, GES-1, HUVEC,
FENG Lan, FENG Lan, CHEN Dewei, CHEN Dewei, GAO Wenxiang   +4 more
doaj   +1 more source

Altitude-related cough [PDF]

Cough, 2013
Altitude-related cough is a troublesome condition of uncertain aetiology that affects many visitors to high altitude. The traditionally held belief that it was due solely to the inspiration of cold, dry air was refuted by observations and experiments in long duration hypobaric chamber studies.
openaire   +2 more sources

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

The Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella   +3 more
wiley   +1 more source

Much more than their fangs: Macroscopic anatomy of the brain of Bothrops moojeni Hoge 1966 (Squamata, Serpentes, Viperidae)

The Anatomical Record, EarlyView.
Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo, Júlio César Costa de Souza, Angele Martins   +2 more
wiley   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

The expression of CTLA-4 in hepatic alveolar echinococcosis patients and blocking CTLA-4 to reverse T cell exhaustion in Echinococcus multilocularis-infected mice

Frontiers in Immunology
Alveolar echinococcosis (AE) is a zoonotic parasitic disease caused by the infection of Echinococcus multilocularis (E. multilocularis) larvae. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) produces inhibitory signals and induces T cell exhaustion, thereby ...
Yuxuan Yang, Yuxuan Yang, Tana Wuren, Binjie Wu, Binjie Wu, Shilei Cheng, Shilei Cheng, Haining Fan, Haining Fan   +8 more
doaj   +1 more source

Cutting Through the Green: A Case for Grassland Archaeology Using UAV Multispectral Data

Archaeological Prospection, EarlyView.
ABSTRACT Advances in low‐altitude remote sensing are needed to improve the effectiveness of archaeological prospection in the Netherlands. The geomorphological situation and land use history make applying various remote sensing and geophysical technologies particularly challenging.
Roeland Emaus
wiley   +1 more source

Hypoxia promotes progression of cervical cancer by modulating the ATXN3-enhanced P53 stability or STAT5 phosphorylation

Cell Death Discovery
This study examines hypoxia’s role in regulating ATXN3 (ATXN3) across cervical cancer subtypes and its impact on tumor progression. We analyzed ATXN3 expression in clinical samples and cell lines (C33A, HeLa, SiHa), assessing proliferation/migration ...
Rong Zhang, Shengjun Chai, Fengjuan Zhang, Jiaming Lai, Rui Wang, Guocai Xu, Xiaoxia Fan, Botong Li, Chunmei Cai   +8 more
doaj   +1 more source

High altitude flying [PDF]

This note investigates the effect of high altitude or low atmospheric pressure upon the operation of an engine and the effect of the low pressure and lack of oxygen and of the very low temperatures upon the pilot and upon the performance of the airplane ...
Carroll, Thomas, King, Paul B
core   +1 more source