Results 11 to 20 of about 6,017 (174)

Vertical transmission of avian leukosis virus subgroup J (ALV-J) from hens infected through artificial insemination with ALV-J infected semen [PDF]

BMC Veterinary Research, 2017
Background Avian leukosis virus (ALV) is one of the main causes of tumour development within the poultry industry in China. The subgroup J avian leukosis viruses (ALV-J), which induce erythroblastosis and myelocytomatosis, have the greatest pathogenicity
Yang Li, Shuai Cui, Weihua Li, Yixin Wang, Zhizhong Cui, Peng Zhao, Shuang Chang   +6 more
doaj   +5 more sources

A balanced game: chicken macrophage response to ALV-J infection [PDF]

Veterinary Research, 2019
Avian leukosis virus subgroup J (ALV-J) infection can cause tumors and immunosuppression in infected chickens. Macrophages play a central role in host defense against invading pathogens.
Min Feng, Tingting Xie, Yuanfang Li, Nan Zhang, Qiuyuan Lu, Yaohong Zhou, Meiqing Shi, Jingchen Sun, Xiquan Zhang   +8 more
doaj   +6 more sources

MiR-34b-5p Suppresses Melanoma Differentiation-Associated Gene 5 (MDA5) Signaling Pathway to Promote Avian Leukosis Virus Subgroup J (ALV-J)-Infected Cells Proliferaction and ALV-J Replication. [PDF]

Front Cell Infect Microbiol, 2017
Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus that has a similar replication cycle to multiple viruses and therefore can be used as a model system for viral entry into host cells. However, there are few reports on the genes or microRNAs (miRNAs) that are responsible for the replication of ALV-J.
Li Z, Luo Q, Xu H, Zheng M, Abdalla BA, Feng M, Cai B, Zhang X, Nie Q, Zhang X.   +9 more
europepmc   +5 more sources

Generierung ALV-J resistenter Hühner mittels Gen-Editierung [PDF]

, 2021
ALV-J ist ein onkogenes, immunsuppressives Retrovirus, welches in Hühnern die myeloische Leukose und andere Tumore, Wachstums- und Legedepression verursachen kann.
Klinger, Romina Chantal
core   +2 more sources

Autophagy-mediated TET2 degradation by ALV-J Env protein suppresses innate immune activation to promote viral replication [PDF]

Journal of Virology
Avian leukosis virus subgroup J (ALV-J) poses a significant threat to the poultry industry; yet, our understanding of its replication and pathogenic mechanisms is limited.
Shihao Chen, Jiaxing Wang, Qiangzhou Wang, Yuyu Ping, Ting Yang, Kejiao Ma, Shiyu Pan, Yulin Bi, Hao Bai, Guobin Chang   +9 more
doaj   +2 more sources

ALV-J GP37 molecular analysis reveals novel virus-adapted sites and three tyrosine-based Env species. [PDF]

PLoS ONE, 2015
Compared to other avian leukosis viruses (ALV), ALV-J primarily induces myeloid leukemia and hemangioma and causes significant economic loss for the poultry industry. The ALV-J Env protein is hypothesized to be related to its unique pathogenesis. However,
Jianqiang Ye, Zhonglei Fan, Jianjun Shang, Xiaoyan Tian, Jialiang Yang, Hongjun Chen, Hongxia Shao, Aijian Qin   +7 more
doaj   +3 more sources

An Endogenous Retroviral LTR-Derived Long Noncoding RNA lnc-LTR5B Interacts With BiP to Modulate ALV-J Replication in Chicken Cells [PDF]

Frontiers in Microbiology, 2021
Infection with the avian leukosis virus subgroup J (ALV-J) impairs host genes and facilitates the establishment of chronic infection and the viral life cycle.
Shihao Chen, Shihao Chen, Shihao Chen, Ruihan Zhao, Ruihan Zhao, Ting Wu, Ting Wu, Dedong Wang, Dedong Wang, Biao Wang, Biao Wang, Shiyu Pan, Shiyu Pan, Xuming Hu, Xuming Hu, Zhiming Pan, Hengmi Cui, Hengmi Cui, Hengmi Cui   +18 more
doaj   +2 more sources

The expression level of chicken telomerase reverse transcriptase in tumors induced by ALV-J is positively correlated with methylation and mutation of its promoter region [PDF]

Veterinary Research, 2022
Avian leukosis virus subgroup J (ALV-J) can cause neoplastic diseases in poultry and is still widely prevalent in China. Chicken telomerase reverse transcriptase (chTERT) is the core component of telomerase, which is closely related to the occurrence and
Yong Xiang, Qinxi Chen, Qingbo Li, Canxin Liang, Weisheng Cao   +4 more
doaj   +2 more sources

Advances on ALV-J in China over the past two decades

Journal of Integrative Agriculture
Avian leukosis is an important tumorigenic disease caused by the avian leukosis virus (ALV) in poultry. ALVs belong to the retroviral family and are classified into 11 subgroups (ALV-A to ALV-K). Among them, ALV-J was first introduced into China in 1999,
Wenrui Fan, Yuntong Chen, Mengmeng Yu, Yongzhen Liu, Yulong Gao   +4 more
doaj   +2 more sources

Conservation and distribution of the DRACH motif for potential m6A sites in avian leukosis virus subgroup J [PDF]

Frontiers in Veterinary Science
N6-methyladenosine (m6A) methylation is an internal post-transcriptional modification that has been linked to viral multiplication and pathogenicity. To elucidate the conservation patterns of potential 5′-DRACH-3′ motifs in avian leukosis virus subgroup ...
Jun Ji, Xinhao Mu, Shuqi Xu, Xin Xu, Zhibin Zhang, Lunguang Yao, Qingmei Xie, Yingzuo Bi   +7 more
doaj   +3 more sources