Effects of cromakalim (BRL 34915) on potassium conductances in CA3 neurons of the guinea-pig hippocampus in vitro [PDF]
The action of the potassium channel activator, cromakalim (BRL 34915), on membrane potential, input resistance and current-voltage-relationship of CA3 neurons in a slice preparation of the guinea-pig hippocampus was investigated by means of intracellular
Alzheimer, Christian +2 more
core +1 more source
Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer +60 more
core +1 more source
The low KM-phosphodiesterase inhibitor denbufylline enhances neuronal excitability in guinea pig hippocampus in vitro [PDF]
The actions of the phosphodiesterase inhibitor denbufylline on the excitability of hippocampal neurons were investigated by means of extracellular and intracellular recordings.
Alzheimer, Christian +3 more
core +1 more source
Human microglial cells synthesize albumin in brain [PDF]
Albumin has been implicated in Alzheimer's disease since it can bind to and transport amyloid beta, the causative agent; albumin is also a potent inhibitor of amyloid beta polymerization.
Bonghee Lee +9 more
core +5 more sources
Transient and selective blockade of adenosine A1-receptors by 8-cyclopentyl-1,3-dipropylxanthine (DPCPX) causes sustained epileptiform activity in hippocampal CA3 neurons of guinea pigs [PDF]
The effects of endogenously released adenosine on the excitability of hippocampal neurons were studied using the novel and highly selective adenosine A1-receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine (DPCPX).
Alzheimer, Christian +2 more
core +1 more source
Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer\u27s disease [PDF]
Interest in understanding the roles of white matter (WM) inflammation and damage in the pathophysiology of Alzheimer disease (AD) has been growing significantly in recent years.
Ances, Beau M +14 more
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Oral and Written Naming in Alzheimer's Disease: A Longitudinal Study [PDF]
This research was supported by Grant PSI2015-64174-P from the Spanish ...
Cuetos Vega, Fernando +2 more
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Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies [PDF]
Acknowledgments This work was supported by The Croatian Science Foundation grant No. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Babić Leko, Mirjana +11 more
core +3 more sources
Preventing the Unnecessary Losses of Alzheimer\u27s Disease [PDF]
Educational Objectives 1. To state the importance of early detection and diagnosis of Alzheimer\u27s disease. 2. To describe common concerns of people in the early stages of Alzheimer\u27s disease. 3.
Noyes, Lin E.
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The Notebook: An Accidental Alzheimer\u27s Awareness Campaign [PDF]
My paper examines and critiques the portrayal of Alzheimer¹s disease in the popular film, The Notebook. Based off of a Nicholas Sparks novel, The Notebook uses Alzheimer¹s disease as a vehicle to relay a love story, but in doing so, presents a distorted ...
Waldron, Danielle
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