Results 1 to 10 of about 530,865 (344)
Ameliorative effect of carveol on scopolamine induced memory impairment in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Carveol is a naturally occurring terpenoid with antispasmodic, carminative, astringent, indigestion, and dyspepsia properties, as well as anti-diabetic, anti-oxidant, anti-hyperlipidemia, and anti-inflammatory properties in the liver ...Komal Latif, Saneela Saneela, Arif-ullah Khan +2 moredoaj +1 more sourceLecanemab in Early Alzheimer's Disease.
New England Journal of Medicine, 2022 BACKGROUND
The accumulation of soluble and insoluble aggregated amyloid-beta (Aβ) may initiate or potentiate pathologic processes in Alzheimer's disease.C. V. van Dyck, C. Swanson, P. Aisen, R. Bateman, Christopher Chen, M. Gee, M. Kanekiyo, David Li, L. Reyderman, S. Cohen, L. Froelich, S. Katayama, M. Sabbagh, B. Vellas, David Watson, S. Dhadda, M. Irizarry, L. Kramer, T. Iwatsubo +18 moresemanticscholar +1 more sourceA randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress
Scientific Reports, 2023 Although beta-amyloid (Aβ) and phosphorylated tau remain the preferred targets for disease-modifying treatments (DMT) against Alzheimer’s disease (AD), part of the pathophysiological mechanisms of cognitive impairment are related to neuroinflammation and Xavier Morató, Marta Marquié, Juan Pablo Tartari, Asunción Lafuente, Carla Abdelnour, Montserrat Alegret, Sara Jofresa, Mar Buendía, Ana Pancho, Núria Aguilera, Marta Ibarria, Susana Diego, Rosario Cuevas, Laia Cañada, Anna Calvet, Ester Esteban-De Antonio, Alba Pérez-Cordón, Ángela Sanabria, Itziar de Rojas, Raúl Nuñez-Llaves, Amanda Cano, Adelina Orellana, Laura Montrreal, Pilar Cañabate, Maitée Rosende-Roca, Liliana Vargas, Urszula Bojaryn, Mario Ricciardi, Diana M. Ariton, Ana Espinosa, Gemma Ortega, Nathalia Muñoz, Núria Lleonart, Emilio Alarcón-Martín, Mariola Moreno, Silvia Preckler, Natalia Tantinya, Maribel Ramis, Ana Belen Nogales, Susanna Seguer, Elvira Martín, Vanesa Pytel, Sergi Valero, Miren Gurruchaga, Lluís Tárraga, Agustín Ruiz, Mercè Boada +46 moredoaj +1 more sourceAutomatized FACEmemory® scoring is related to Alzheimer’s disease phenotype and biomarkers in early-onset mild cognitive impairment: the BIOFACE cohort
Alzheimer’s Research & Therapy, 2022 Background FACEmemory® is the first computerized, self-administered verbal episodic memory test with voice recognition. It can be conducted under minimal supervision and contains an automatic scoring system to avoid administrator errors.Montserrat Alegret, Oscar Sotolongo-Grau, Ester Esteban de Antonio, Alba Pérez-Cordón, Adelina Orellana, Ana Espinosa, Silvia Gil, Daniel Jiménez, Gemma Ortega, Angela Sanabria, Natalia Roberto, Isabel Hernández, Maitee Rosende-Roca, Juan Pablo Tartari, Emilio Alarcon-Martin, Itziar de Rojas, Laura Montrreal, Xavier Morató, Amanda Cano, Dorene M. Rentz, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Marta Marquié, Mercè Boada +24 moredoaj +1 more sourceDifferences in macular vessel density in the superficial plexus across cognitive impairment: the NORFACE cohort
Scientific Reports, 2022 Optical coherence tomography angiography (OCT-A) allows the detection of retinal vessel density (VD) loss, which is a reflection of brain vascular pathology. We aimed to investigate differences in macular VD in the superficial plexus in a large cohort of Marta Marquié, Sergi Valero, Joan Martínez, Emilio Alarcón-Martín, Ainhoa García-Sánchez, Itziar de Rojas, Miguel Castilla-Martí, Luis Castilla-Martí, Isabel Hernández, Maitée Rosende-Roca, Liliana Vargas, Juan Pablo Tartari, Ester Esteban-De Antonio, Urszula Bojaryn, Vanesa Pytel, Leire Narvaiza, Montserrat Alegret, Gemma Ortega, Ana Espinosa, Ángela Sanabria, Alba Pérez-Cordón, Núria Lleonart, Nathalia Muñoz, Lluís Tárraga, Agustín Ruiz, Mercè Boada +25 moredoaj +1 more source2021 Alzheimer's disease facts and figures
Alzheimer's & Dementia, 2021 This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on caregivers and society. The Special Report discusses the challenges Anonymoussemanticscholar +1 more sourceNew insights into the genetic etiology of Alzheimer’s disease and related dementias
Nature Genetics, 2022 Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes.C. Bellenguez, Fahri Küçükali, I. Jansen, L. Kleineidam, S. Moreno-Grau, N. Amin, A. Naj, Rafael Campos-Martin, B. Grenier‐Boley, V. Andrade, P. Holmans, A. Boland, V. Damotte, S. J. van der Lee, M. R. Costa, T. Kuulasmaa, Qiong Yang, I. de Rojas, J. Bis, A. Yaqub, I. Prokić, J. Chapuis, S. Ahmad, V. Giedraitis, D. Aarsland, P. García-González, C. Abdelnour, E. Alarcón‐Martín, D. Alcolea, M. Alegret, I. Álvarez, V. Álvarez, N. Armstrong, A. Tsolaki, C. Antunez, I. Appollonio, M. Arcaro, S. Archetti, A. Pastor, B. Arosio, L. Athanasiu, H. Bailly, N. Banaj, M. Baquero, S. Barral, A. Beiser, A. Pastor, J. Below, Penelope H. Benchek, L. Benussi, C. Berr, C. Besse, Valentina Bessi, G. Binetti, Alessandra Bizarro, R. Blesa, M. Boada, E. Boerwinkle, B. Borroni, S. Boschi, P. Bossù, G. Bråthen, J. Bressler, Catherine Bresner, H. Brodaty, K. Brookes, L. Brusco, D. Buiza‐Rueda, K. Bûrger, V. Burholt, W. Bush, M. Calero, L. Cantwell, G. Chêne, Jaeyoon Chung, M. Cuccaro, Á. Carracedo, R. Cecchetti, Laura Cervera-Carles, C. Charbonnier, Hung-Hsin Chen, C. Chillotti, S. Ciccone, J. Claassen, C. Clark, E. Conti, A. Corma-Gómez, E. Costantini, C. Custodero, D. Daian, M. C. Dalmasso, A. Daniele, E. Dardiotis, J. Dartigues, P. D. de Deyn, K. de Paiva Lopes, L. D. de Witte, S. Debette, J. Deckert, T. del Ser, N. Denning, A. Destefano, M. Dichgans, J. Diehl-Schmid, M. Diez-Fairen, P. Rossi, S. Djurovic, E. Duron, E. Düzel, C. Dufouil, G. Eiriksdottir, S. Engelborghs, V. Escott-Price, A. Espinosa, M. Ewers, K. Faber, Tagliavini Fabrizio, S. F. Nielsen, D. Fardo, L. Farotti, C. Fenoglio, M. Fernandez-Fuertes, R. Ferrari, Catarina B. Ferreira, E. Ferri, B. Fin, P. Fischer, T. Fladby, K. Fliessbach, Bernard Fongang, M. Fornage, J. Fortea, T. Foroud, Silvia Fostinelli, Nick C Fox, E. Franco-Macías, M. Bullido, A. Frank‐García, L. Froelich, B. Fulton-Howard, D. Galimberti, J. M. García-Alberca, P. García-González, S. García-Madrona, G. García-Ribas, R. Ghidoni, I. Giegling, Giaccone Giorgio, A. Goate, O. Goldhardt, Duber Gomez-Fonseca, A. Gonzáléz-Pérez, C. Graff, G. Grande, E. Green, T. Grimmer, E. Grünblatt, M. Grunin, V. Gudnason, Tamar Guetta‐Baranés, A. Haapasalo, G. Hadjigeorgiou, J. Haines, K. Hamilton-Nelson, H. Hampel, O. Hanon, J. Hardy, A. Hartmann, L. Hausner, J. Harwood, S. Heilmann-Heimbach, S. Helisalmi, M. Heneka, I. Hernández, M. Herrmann, P. Hoffmann, C. Holmes, H. Holstege, Raquel Huerto Vilas, M. Hulsman, J. Humphrey, G. Biessels, X. Jian, C. Johansson, G. Jun, Y. Kastumata, J. Kauwe, P. Kehoe, L. Kilander, A. Ståhlbom, M. Kivipelto, A. Koivisto, J. Kornhuber, M. Kosmidis, W. Kukull, Pavel P. Kuksa, B. Kunkle, A. Kuzma, C. Lage, E. Laukka, L. Launer, A. Lauria, Chien-Yueh Lee, J. Lehtisalo, O. Lerch, A. Lleó, W. Longstreth, O. Lopez, A. L. de Munain, S. Love, Malin Löwemark, L. Luckcuck, K. Lunetta, Yiyi Ma, J. Macías, C. MacLeod, W. Maier, F. Mangialasche, M. Spallazzi, M. Marquié, R. Marshall, E. R. Martin, Angel Martin Montes, Carmen Martínez Rodríguez, C. Masullo, R. Mayeux, S. Mead, P. Mecocci, M. Medina, A. Meggy, S. Mehrabian, S. Mendoza, M. Menéndez-González, P. Mir, S. Moebus, M. Mol, L. Molina-Porcel, L. Montrreal, L. Morelli, F. Moreno, K. Morgan, T. Mosley, M. Nöthen, C. Muchnik, S. Mukherjee, B. Nacmias, T. Ngandu, G. Nicolas, B. Nordestgaard, R. Olaso, A. Orellana, Michela Orsini, G. Ortega, A. Padovani, Caffarra Paolo, G. Papenberg, L. Parnetti, F. Pasquier, P. Pastor, G. Peloso, A. Pérez-Cordón, J. Pérez-Tur, Pierre Pericard, O. Peters, Y. Pijnenburg, J. Pineda, G. Piñol-Ripoll, C. Pisanu, T. Polak, J. Popp, D. Posthuma, J. Priller, R. Puerta, O. Quenez, I. Quintela, J. Thomassen, A. Rábano, I. Rainero, F. Rajabli, I. Ramakers, L. Real, M. Reinders, C. Reitz, D. Reyes-Dumeyer, P. Ridge, S. Riedel-Heller, P. Riederer, N. Roberto, E. Rodríguez-Rodríguez, A. Rongve, I. Allende, M. Rosende-Roca, J. Royo, E. Rubino, D. Rujescu, M. Sáez, P. Sakka, I. Saltvedt, Á. Sanabria, M. B. Sánchez-Arjona, F. Sánchez-García, P. S. Juan, R. Sánchez-Valle, S. Sando, C. Sarnowski, C. Satizabal, M. Scamosci, N. Scarmeas, E. Scarpini, P. Scheltens, N. Scherbaum, M. Scherer, M. Schmid, A. Schneider, J. Schott, G. Selbæk, D. Seripa, M. Serrano, Jin Sha, A. Shadrin, O. Skrobot, S. Slifer, G. Snijders, H. Soininen, V. Solfrizzi, A. Solomon, Yeunjoo E. Song, S. Sorbi, O. Sotolongo-Grau, G. Spalletta, A. Spottke, A. Squassina, E. Stordal, Juan Pablo Tartan, L. Tárraga, N. Tesi, A. Thalamuthu, Tegos Thomas, G. Tosto, L. Traykov, L. Tremolizzo, A. Tybjærg‐Hansen, A. Uitterlinden, Abbe Ullgren, I. Ulstein, S. Valero, O. Valladares, C. Broeckhoven, J. Vance, B. Vardarajan, A. van der Lugt, Jasper Van Dongen, Jeroen G J van Rooij, J. V. van Swieten, R. Vandenberghe, F. Verhey, J. Vidal, Jonathan S. Vogelgsang, M. Vyhnálek, Michael Wagner, D. Wallon, Li-San Wang, Ruiqi Wang, L. Weinhold, J. Wiltfang, Gill Windle, B. Woods, M. Yannakoulia, Habil Zare, Yi Zhao, Xiaoling Zhang, Congcong Zhu, M. Zulaica, L. Farrer, B. Psaty, M. Ghanbari, T. Raj, P. Sachdev, K. Mather, F. Jessen, M. A. Ikram, A. de Mendonça, J. Hort, M. Tsolaki, M. Pericak-Vance, P. Amouyel, Julie Williams, R. Frikke-Schmidt, J. Clarimón, J. Deleuze, G. Rossi, S. Seshadri, O. Andreassen, M. Ingelsson, M. Hiltunen, K. Sleegers, G. Schellenberg, C. V. van Duijn, R. Sims, W. M. van der Flier, A. Ruiz, A. Ramírez, J. Lambert +402 moresemanticscholar +1 more source
