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Clinical diagnosis of Alzheimer's disease [PDF]

open access: bronzeNeurology, 1984
Clinical criteria for the diagnosis of Alzheimer's disease include insidious onset and progressive impairment of memory and other cognitive functions. There are no motor, sensory, or coordination deficits early in the disease.
Guy M. McKhann   +5 more
openalex   +2 more sources

Association between BrainAGE and Alzheimer's disease biomarkers [PDF]

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION The brain age gap estimation (BrainAGE) method uses a machine learning model to generate an age estimate from structural magnetic resonance imaging (MRI) scans. The goal was to study the association of brain age with Alzheimer's disease (AD)
Yousaf Abughofah   +16 more
doaj   +2 more sources

2023 Alzheimer's disease facts and figures

open access: yesAlzheimer's & Dementia, 2023
This article describes the public health impact of Alzheimer's disease, including prevalence and incidence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society.

semanticscholar   +1 more source

Barriers and facilitators to participating in Alzheimer's disease biomarker research in black and white older adults

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023
Introduction The study examined Black and White prospective participants’ views of barriers to and facilitators of participation in Alzheimer's disease (AD) biomarker research.
Johanne Eliacin   +12 more
doaj   +1 more source

Stability and change in acculturation‐related characteristics in older Latinos: Implications for culturally compatible ADRD research

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023
Introduction Acculturation‐related characteristics, that is, factors directly connected to culture and familial relationships, are associated with engaged research participation within Latino communities.
Melissa Lamar   +6 more
doaj   +1 more source

Preliminary report of Iranian Registry of Alzheimer's disease in Tehran province: A cross‐sectional study in Iran

open access: yesHealth Science Reports, 2022
Background and Aims Alzheimer's disease (AD) is the main cause of dementia and over the 55 million people live with dementia worldwide. We aimed to establish the first database called the Iranian Alzheimer's Disease Registry to create a powerful source ...
Javad Fahanik‐Babaei   +19 more
doaj   +1 more source

Neuropsychiatric symptoms in Brazilians with mild cognitive impairment and dementia

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Introduction Knowledge is limited about behavioral and psychological symptoms of mild cognitive impairment (MCI) and dementia in racial and ethnic minorities.
Robert S. Wilson   +6 more
doaj   +1 more source

Relationship of fasting glucose and longitudinal Alzheimer's disease imaging markers

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction Fasting glucose increases with age and is linked to modifiable Alzheimer's disease risk factors such as cardiovascular disease and Type 2 diabetes (T2D).
Robyn A. Honea   +9 more
doaj   +1 more source

ARIA in patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2023
INTRODUCTION Lecanemab is a humanized immunoglobulin G1 (IgG1) monoclonal antibody that preferentially targets soluble aggregated Aβ species (protofibrils) with activity at amyloid plaques.
Lawrence S. Honig   +8 more
doaj   +1 more source

Lecanemab in Early Alzheimer's Disease.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND The accumulation of soluble and insoluble aggregated amyloid-beta (Aβ) may initiate or potentiate pathologic processes in Alzheimer's disease.
C. V. van Dyck   +18 more
semanticscholar   +1 more source

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