Results 131 to 140 of about 709,465 (344)

5-Hydroxymethylcytosine Signatures in Circulating Cell-Free DNA as Diagnostic Biomarkers for Late-Onset Alzheimer’s Disease [PDF]

open access: green, 2021
Lei Chen   +8 more
openalex   +1 more source

On bloodvessel branching analysis for the detection of Alzheimer's disease

open access: yes, 2014
Alzheimer’s Disease (AD) is increasingly prevalent in modern society and methods for its diagnosis are only just starting to emerge. Given images of brain tissue, we show how Alzheimer’s disease can be detected from the branching structures of blood ...
Carare, Roxana O.   +2 more
core  

The Degeneration of the Human Mind: An Analysis of Alzheimer’s Disease, A Kuhnian Perspective [PDF]

open access: yes, 2013
In 1906, a German physician, Dr. Alois Alzheimer, specifically identified a collection of brain cell abnormalities (and the formation of plaque in the brain) as a disease, which forever changed the way scientists view degenerative cognitive disorders ...
Ilg, Genevieve
core   +1 more source

Additional file 1: of A phase III randomized trial of gantenerumab in prodromal Alzheimerâ s disease

open access: yes, 2017
List of institutional review boards and independent ethics committees. (DOCX 20 kb)
Ostrowitzki, Susanne   +16 more
openaire   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones   +3 more
wiley   +1 more source

Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy

open access: yesNature Communications
Neurotransmitter release occurs through exocytosis of synaptic vesicles. α-Synuclein’s function and dysfunction in Parkinson’s disease and other synucleinopathies is thought to be tightly linked to synaptic vesicle binding. Age is the biggest risk factor
Virginia Gao   +15 more
doaj   +1 more source

Social capabilities in Alzheimer’s patients [PDF]

open access: yes
Patients with stage-I (very mild and mild) Alzheimer’s disease were asked to participate in a Dictator Game, a type of game in which a subject has to decide how to allocate a certain amount of money between himself and another person.
Antoni Bosch-Domènech   +2 more
core  

Additional file 1: of PU.1 regulates Alzheimerâ s disease-associated genes in primary human microglia

open access: yes, 2018
Table S1. List of cases. List of cases used for all studies. (DOCX 19 kb)
Rustenhoven, Justin   +16 more
openaire   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

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