Results 151 to 160 of about 672,318 (344)

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

open access: yesArthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard   +15 more
wiley   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

open access: yesAdvanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang   +13 more
wiley   +1 more source

Additional file 1: of Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimerâ s disease

open access: yes, 2019
Table S1. Participantsâ family mutations. (DOCX 17 kb)
Weston, Philip   +12 more
openaire   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

open access: yesAdvanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams   +7 more
wiley   +1 more source

On bloodvessel branching analysis for the detection of Alzheimer's disease

open access: yes, 2014
Alzheimer’s Disease (AD) is increasingly prevalent in modern society and methods for its diagnosis are only just starting to emerge. Given images of brain tissue, we show how Alzheimer’s disease can be detected from the branching structures of blood ...
Carare, Roxana O.   +2 more
core  

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Additional file 8: of Beneficial effects of curtailing immune susceptibility in an Alzheimerâ s disease model

open access: yes, 2019
Table S1. List of all antibodies used, with respective working dilutions for either WB or IHF, as well as Companies of origin and catalog number specification. (PDF 290 kb)
Benedetto, Giulia Di   +8 more
openaire   +1 more source

Ultrasonic Atomization Spray Coating of PCL on an Mg‐Based Alloy Enhanced by Plasma Electrolytic Oxidation for Improved Adhesion, Corrosion Resistance, and Biocompatibility

open access: yesAdvanced Engineering Materials, EarlyView.
Plasma electrolytic oxidation is combined with ultrasonic spray deposition of polycaprolactone (PCL) on WE43 magnesium alloy to improve adhesion, corrosion resistance, and cytocompatibility. The hybrid coating demonstrates significantly reduced hydrogen evolution and enhances mechanical bonding, offering a promising strategy for next‐generation ...
Seyed Masih Mousavizadeh   +9 more
wiley   +1 more source

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