Results 101 to 110 of about 157,234 (246)

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience [PDF]

open access: yes, 2008
Background: Dementia results from heterogeneous diseases of the brain. Mixed disease forms are increasingly recognized. Methods: We performed a survey within brain banks of BrainNet Europe to estimate the proportion of mixed disease forms underlying ...
Al-Sarraj, Safa   +15 more
core   +1 more source

Additional file 6: of Beneficial effects of curtailing immune susceptibility in an Alzheimerâ s disease model

open access: yes, 2019
Figure S6. Negative controls for Fig. 8, panel a (Aβ1â 42 expression). Negative controls are reported in all panels marked with acronyms of secondary antibodies labeled with, respectively, Texas Red (TR) (PDF 455 kb)
Benedetto, Giulia Di   +8 more
openaire   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Pharmacotherapy Of Alzheimer′s Disease

open access: yesAnnals of Indian Academy of Neurology, 2001
Alzheimer′s disease is characterized by degeneration of various structures in the brain, with development of amyloid plaques and neurofibrillary tangles. Deficiencies of acetylcholine and other neurotransmitters also occur.
Migalni Jasdeep, Chahil Ritu
doaj  

Dual Attention Convolutional AutoEncoder for Diagnosis of Alzheimer’s Disorder in Patients Using Neuroimaging and MRI Features

open access: yesIEEE Access
Alzheimer’s disease is a neurodegenerative disease causing memory loss and brain protein accumulation. Early diagnosis is crucial for clinical trials and patient care. Magnetic resonance imaging (MRI) methods have improved diagnosis and prognosis,
Shaha Al-Otaibi   +5 more
doaj   +1 more source

Cognitive impairment in older people: its implications for future demand for services and costs [PDF]

open access: yes, 2003
This study aimed to make projections, for the next 30 years, of future numbers of older people with cognitive impairment, their demand for long-term care services and the future costs of their care under a range of specified assumptions.

core  

Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer's Precision Medicine and Pharmacology. [PDF]

open access: yes, 2019
Systems biology studies have demonstrated that different (epi)genetic and pathophysiological alterations may be mapped onto a single tumor's clinical phenotype thereby revealing commonalities shared by cancers with divergent phenotypes.
Goetzl, Edward J   +4 more
core   +2 more sources

Additional file 1: of Role of transient receptor potential ankyrin 1 channels in Alzheimerâ s disease

open access: yes, 2016
Supplementary figures. (PDF 547Â kb)
Kuan-I Lee   +6 more
openaire   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Association Between Interleukin 16 Gene Polymorphisms (rs1131445, rs4072111) and Late Onset of Alzheimer’s Disease in Iranian Patients

open access: yesSālmand, 2016
Objectives: Alzheimer’s disease is the most common kind of dementia in the old age, and its incidence increases with age. Previous studies have shown that cytokines are proteins that play an important role in inflammation, and their level
Nazanin Esmaeili Anvar   +4 more
doaj  

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