Results 161 to 170 of about 25,152,973 (316)

Disease-modifying drugs in Alzheimer's disease

open access: yesDrug Design, Development and Therapy, 2013
Laura Ghezzi, Elio Scarpini, Daniela Galimberti Neurology Unit, Department of Pathophysiology and Transplantation, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy Abstract: Alzheimer's disease (AD)
Ghezzi L, Scarpini E, Galimberti D
doaj  

Dementia caregiving in Utah: Data from the 2016 Behavioral Risk Factor Surveillance System

open access: yes
In Utah, half of all adults providing unpaid care to loved ones with Alzheimer\u2019s or an-other dementia have been doing so for at least two years.This Fact Sheet is supported by Cooperative Agreement #NU58DP006115 from the Centers for Disease Control ...

core  

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

open access: yesAdvanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez   +16 more
wiley   +1 more source

Amyloidopathy in the Eye of Alzheimer′s Disease

open access: yesJournal of Addiction Research & Therapy, 2011
openaire   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

open access: yesAdvanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu   +17 more
wiley   +1 more source

Dementia caregiving in Georgia: Data from the 2016 Behavioral Risk Factor Surveillance System

open access: yes
In Georgia, more than 40 percent of all adults providing unpaid care to loved ones with Alzheimer\u2019s or another dementia have been doing so for at least two years.This Fact Sheet is supported by Cooperative Agreement #NU58DP006115 from the Centers ...

core  

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider   +14 more
wiley   +1 more source

Impact of early intervention and disease modification in patients with predementia Alzheimer’s disease: a Markov model simulation

open access: yesClinicoEconomics and Outcomes Research, 2011
David Budd1, Leah C Burns2, Zhenchao Guo2, Gilbert L’Italien2,3, Pablo Lapuerta11Bristol-Myers Squibb, Princeton, NJ, USA; 2Bristol-Myers Squibb, Wallingford, CT, USA; 3Yale University School of Medicine, New Haven, CT, USABackground: Early ...
Budd D   +4 more
doaj  

Dementia caregiving in Montana: Data from the 2016 Behavioral Risk Factor Surveillance System

open access: yes
In Montana, more than half of all adults providing unpaid care to loved ones with Alzheimer\u2019s or another dementia have been doing so for at least two years.This Fact Sheet is supported by Cooperative Agreement #NU58DP006115 from the Centers for ...

core  

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