Microglia in Alzheimer Brain: A Neuropathological Perspective [PDF]
, 2012 Microglia have long been noted to be present and activated in Alzheimer brain. Demonstrations that these microglia are associated with the specific lesions of Alzheimer disease—Aβ plaques and neurofibrillary tangles—and that these microglia overexpress ...
Mrak, Robert E.
core +3 more sources
Reduction of Alzheimer's disease beta-amyloid pathology in the absence of gut microbiota [PDF]
arXiv, 2015 Alzheimer's disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder. Despite clinical and experimental evidence implicating the intestinal microbiota in a number of brain disorders, its impact on Alzheimer's disease is not known.
arxiv
Visual Molecular Dynamics Investigations of the Impact of Hydrophobic Nanoparticles on Prognosis of Alzheimer’s Disease and Cancers [PDF]
, 2012 The possible impact of hydrophobic lectin nanoparticles on the prognosis and progression of Alzheimer's disease (AD) and cancers was investigated by Visual Molecular Dynamics (VMD) computer modeling programs available from the Beckmann Advanced ...
I. C. Baianu, M Charles, V. I. Prisecaru
core +1 more source
The neuropathological diagnosis of Alzheimer’s disease
Molecular Neurodegeneration, 2019 Alzheimer’s disease is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline, although less common clinical presentations are increasingly recognized.
M. DeTure, D. Dickson
semanticscholar +1 more source
A dynamic mechanism of Alzheimer based on artificial neural network [PDF]
arXiv, 2014 In this paper, we provide another angle to analyze the reasons why Alzheimer Disease exists. We analyze the dynamic mechanism of Alzheimer Disease based on the cognitive model that established from artificial neural network. We can provide some theoretic explanations to Alzheimer Disease through the analyzing of this model.
arxiv
[Anesthesia and Alzheimer disease - Current perceptions] [PDF]
, 2018 BACKGROUND AND OBJECTIVES: It has been speculated that the use of anesthetic agents may be a risk factor for the development of Alzheimer disease.
Lapa, TA, Marques, AF
core +1 more source
Economic burden of Alzheimer disease and managed care considerations.
American Journal of Managed Care, 2020 Alzheimer disease is the most common cause of dementia and the fifth leading cause of death in adults older than 65 years. The estimated total healthcare costs for the treatment of Alzheimer disease in 2020 is estimated at $305 billion, with the cost ...
W. Wong
semanticscholar +1 more source
PAK in Alzheimer disease, Huntington disease and X-linked mental retardation. [PDF]
, 2012 Developmental cognitive deficits including X-linked mental retardation (XLMR) can be caused by mutations in P21-activated kinase 3 (PAK3) that disrupt actin dynamics in dendritic spines.
Cole, Greg M +3 more
core +1 more source
An Ensemble of Deep Convolutional Neural Networks for Alzheimer's Disease Detection and Classification [PDF]
arXiv, 2017 Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's Disease can help for proper treatment and to prevent brain tissue damage. Detection and classification of Alzheimer'
arxiv
Transfer Learning and Class Decomposition for Detecting the Cognitive Decline of Alzheimer Disease [PDF]
arXiv, 2023 Early diagnosis of Alzheimer's disease (AD) is essential in preventing the disease's progression. Therefore, detecting AD from neuroimaging data such as structural magnetic resonance imaging (sMRI) has been a topic of intense investigation in recent years. Deep learning has gained considerable attention in Alzheimer's detection.
arxiv