Results 131 to 140 of about 9,708,599 (370)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
EMBO Molecular Medicine, 2012 Inherited familial Alzheimer's disease (AD) is characterized by small increases in the ratio of Aβ42 versus Aβ40 peptide which is thought to drive the amyloid plaque formation in the brain of these patients.
Francesc X. Guix +13 more
doaj +1 more source
Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology
Molecular Neurodegeneration, 2018 Background Despite diverging levels of amyloid-β (Aβ) and TAU pathology, different mouse models, as well as sporadic AD patients show predictable patterns of episodic memory loss.
Annerieke Sierksma +9 more
doaj +1 more source
Early diagnosis of Alzheimer's disease: update on combining genetic and brain-imaging measures. [PDF]
, 2000 Diagnosis of Alzheimer's disease is often missed or delayed in clinical practice; thus, methods to improve early detection would provide opportunities for early intervention, symptomatic treatment, and improved patient function.
Small, GW
core +1 more source
Altered Brain Serotonin Transporter and Associated Glucose Metabolism in Alzheimer Disease [PDF]
, 2009 Yasuomi Ouchi +5 more
openalex +1 more source
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Computer‐assisted prediction of clinical progression in the earliest stages of AD
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018 Introduction Individuals with subjective cognitive decline (SCD) are at increased risk for clinical progression. We studied how combining different diagnostic tests can help to identify individuals who are likely to show clinical progression.
Hanneke F.M. Rhodius‐Meester +20 more
doaj +1 more source
Cognitive impairment in older people: its implications for future demand for services and costs [PDF]
, 2003 This study aimed to make projections, for the next 30 years, of future numbers of older people with cognitive impairment, their demand for long-term care services and the future costs of their care under a range of specified assumptions.
core
Evidencing inhibitory deficits in Alzheimer?s disease through interference effects and shifting disabilities in the Stroop test [PDF]
, 2003 Hélène Amieva
openalex +1 more source